Results 1 to 10 of about 18,988 (214)

Rabeprazole suppressed gastric intestinal metaplasia through activation of GPX4-mediated ferroptosis [PDF]

Frontiers in Pharmacology
BackgroundGastric intestinal metaplasia is a common pathological feature in patients with Helicobacter pylori (H. pylori) infection. Rabeprazole was widely used as the first-line regimen for H. pylori infectious treatment.
Jing Xie, Xinhua Liang, Fangfang Xie, Canxin Huang, Zijun Lin, Shuping Xie, Fangying Yang, Fengfeng Zheng, Lanlan Geng, Lanlan Geng, Wanfu Xu, Wanfu Xu, Sitang Gong, Sitang Gong, Li Xiang, Li Xiang   +15 more
doaj   +4 more sources

Alcohol consumption and the risk of gastric intestinal metaplasia in a U.S. Veterans population

PLoS ONE, 2021
Background Chronic alcohol use is a risk factor for non-cardia gastric adenocarcinoma. However, it is less well understood whether alcohol use is a risk factor for premalignant mucosal changes, namely gastric intestinal metaplasia.
Hudson M. Holmes, Andre G. Jove, Mimi C. Tan, Hashem B. El-Serag, Aaron P. Thrift   +4 more
doaj   +4 more sources

Is gastric intestinal metaplasia a risk factor for colorectal neoplasms?

Biotechnology & Biotechnological Equipment, 2021
Colorectal cancers are one of the most common types of cancer. Gastric intestinal metaplasia is considered a precancerous lesion that can progress into gastric cancer.
Remzi Beştaş, Nazım Ekin
doaj   +2 more sources

TFF3 initiates gastric intestinal metaplasia by activating JAK2 and STAT3 under high salt conditions [PDF]

Scientific Reports
The mechanism underlying the role of trefoil factor family 3 (TFF3) in intestinal metaplasia remains unclear. This study reveals the molecular mechanism by which TFF3, in the process of gastric mucosal epithelial cell intestinal metaplasia (IM) induced ...
Yanhong Wang, Feifei Qian, Baodong Shan, Li Zhang, Jie Zhong, Song Chen, Manman Yao, Shengnan Li, Xixiang Cao, Sujuan Fei, Xunlei Pang   +10 more
doaj   +2 more sources

IS PREDICTION OF RENAL FAILURE WITH ITS INDICES FEASIBLE WITH PRESENCE OF HISTOPATHOLOGIC EVIDENCE FOR GASTRIC INTESTINAL METAPLASIA ?

Sanamed, 2019
Objectives: Gastric intestinal metaplasia have traditionally been associated with gastric adenocarcinoma. Gastric intestinal metaplasia is usually related to the Helicobacter pylori infection, older ages, smoking history, consumption of strong spicy ...
Sengul Demet
doaj   +3 more sources

Advances in modeling gastric intestinal metaplasia: a comprehensive review of experimental models and mechanistic insights [PDF]

Frontiers in Oncology
Epithelial cells within the gastric corpus mucosa exhibit a dynamic response to injury, characterized by alterations in gene transcription, cellular phenotype, and tissue organization, collectively termed metaplasia.
Xinyuan Liu, Xinyuan Liu, Xinyuan Liu, Xinyuan Liu, Xinyuan Liu, Kaiqi Yang, Kaiqi Yang, Kaiqi Yang, Kaiqi Yang, Kaiqi Yang, Nan Zhang, Nan Zhang, Nan Zhang, Nan Zhang, Nan Zhang, Xiujing Sun, Xiujing Sun, Xiujing Sun, Xiujing Sun, Xiujing Sun   +19 more
doaj   +2 more sources

CDX2-induced intestinal metaplasia in human gastric organoids derived from induced pluripotent stem cells

iScience, 2022
Summary: Intestinal metaplasia is related to gastric carcinogenesis. Previous studies have suggested the important role of CDX2 in intestinal metaplasia, and several reports have shown that the overexpression of CDX2 in mouse gastric mucosa caused ...
Takahiro Koide, Michiyo Koyanagi-Aoi, Keiichiro Uehara, Yoshihiro Kakeji, Takashi Aoi   +4 more
doaj   +1 more source

Analysis of Probable Risk Factors of Gastric Intestinal Metaplasia in Patients Referred to the Gastroenterology Clinic with Dyspepsia

Asian Pacific Journal of Cancer Biology, 2023
Background: Gastric intestinal metaplasia is known as a precursor of gastric cancer in the cascade of events from chronic gastritis to gastric adenocarcinoma.
Leila Mahmoudieh, Naghmeh Salarieh, Mojgan Forootan, Somayeh Fatemizadeh, Pardis Ketabi Moghadam   +4 more
doaj   +1 more source

Shared features of metaplasia and the development of adenocarcinoma in the stomach and esophagus

Frontiers in Cell and Developmental Biology, 2023
Introduction: Plasticity is an inherent property of the normal gastrointestinal tract allowing for appropriate response to injury and healing. However, the aberrancy of adaptable responses is also beginning to be recognized as a driver during cancer ...
Yongji Zeng, Qing K. Li, Sujayita Roy, Jason C. Mills, Jason C. Mills, Ramon U. Jin   +5 more
doaj   +1 more source

OLGA- and OLGIM-Based Staging in the Patients with Gastritis and Endoscopy Indications

The Turkish Journal of Gastroenterology, 2022
Background: Gastric cancer is one of the most common cancers with high mortality. In Iran, the high-risk regions include Northern and Northwestern parts.
Fariborz Mansour-Ghanaei, Farahnaz Joukar, Sara Yeganeh, Mahbobeh Sadeghi, Arash Daryakar, Masood Sepehrimanesh   +5 more
doaj   +1 more source