Molecular Alterations in Gastric Intestinal Metaplasia [PDF]
Gastric cancer (GC) remains one of the most common causes of mortality worldwide. Intestinal metaplasia (IM) is one of the preneoplastic gastric lesions and is considered an essential predisposing factor in GC development. Here we present a review of recent most relevant papers to summarize major findings on the molecular alterations in gastric IM. The
Paulius Jonaitis +2 more
openaire +2 more sources
Gastric intestinal metaplasia [PDF]
We read with interest the article by Dinis-Ribeiro et al concerning a follow up model for patients with atrophic gastritis and intestinal metaplasia (IM).1 The model proposed is based on “a minimum of two endoscopic biopsies”, although 40% of patients had at least three biopsies, and more than 15% of patients had more than four biopsies performed ...
C A Rubio, R Befrits
openaire +1 more source
The Role of Endoscopic Grading of Gastric Intestinal Metaplasia (EGGIM) in Assessing the Extent and Degree of Gastric Intestinal Metaplasia. [PDF]
ABSTRACTObjectivesWe aimed to evaluate the consistency between endoscopic grading of gastric intestinal metaplasia (EGGIM) and the operative link on gastric intestinal metaplasia assessment (OLGIM) staging, as well as the value of endoscopic grading of gastric intestinal metaplasia (GIM) in early gastric cancer (EGC) risk.MethodsThe sample size was ...
Lyu D, Zhao J, Jin HF, Lyu B.
europepmc +3 more sources
Gastric intestinal metaplasia (GIM), which denotes conversion of gastric mucosa into an intestinal phenotype, can occur in all regions of the stomach, including cardiac, fundic, and pyloric mucosa. Since the earliest description of GIM, its association with gastric cancer of the differentiated (intestinal) type has been a well-recognized concern.
Sugano, Kentaro +2 more
openaire +1 more source
Gastric carcinoma and intestinal metaplasia significance of types of intestinal metaplasia upon development of gastric carcinoma [PDF]
For clarifying significance of subtypes of intestinal metaplasia upon the development of stomach carcinoma, 34 stomachs surgically removed for mucosal carcinoma were morphologically studied. Intestinal metaplasia was divided into incomplete and complete types by alcian blue-PAS staining.
F, Iida, J, Kusama
openaire +2 more sources
The importance of antioxidant status in gastric intestinal metaplasia [PDF]
Background: Oxidative stress status in different cancer types was investigated before, but not studied in gastric intestinal metaplasia to the best of our knowledge. Purpose of this study is to examine whether there is a difference between oxidative stress status in patients with intestinal metaplasia (IM) compared to individuals without IM, we ...
Danış, Nilay +6 more
openaire +4 more sources
A Role for the Vacuolating Cytotoxin, VacA, in Colonization and Helicobacter pylori-Induced Metaplasia in the Stomach [PDF]
Carriage of Helicobacter pylori strains producing more active (s1/i1) forms of VacA is strongly associated with gas-tric adenocarcinoma. To our knowledge, we are the first to determine effects of different polymorphic forms of VacA on inflammation and ...
Ingram, R J M +21 more
core +1 more source
A case of Helicobacter pylori-negative early gastric adenocarcinoma with gastrointestinal phenotype
A 40-year-old man with slightly depressed (0-IIc) type gastric cancer of the pyloric anterior gastric area underwent pre-operative screening for tetralogy of Fallot and endoscopic submucosal dissection (ESD) and was tested for Helicobacter pylori ...
Masafumi Takatsuna +8 more
doaj +1 more source
Two distinct aetiologies of cardia cancer, evidence from premorbid serological markers of gastric atrophy and Helicobacter pylori status [PDF]
Background: Non-cardia gastric adenocarcinoma is positively associated with Helicobacter pylori infection and atrophic gastritis. The role of H pylori infection and atrophic gastritis in cardia cancer is unclear.
Derakhshan, M.H. +7 more
core +1 more source
BACKGROUND: Short segment Barrett's esophagus is defined by the presence of
Judite Dietz +5 more
doaj +1 more source

