Results 41 to 50 of about 24,665 (187)
Murine Models of Gastric Corpus PreneoplasiaSummary
Cellular and Molecular Gastroenterology and Hepatology, 2017 Intestinal-type gastric adenocarcinoma evolves in a field of pre-existing metaplasia. Over the past 20 years, a number of murine models have been developed to address aspects of the physiology and pathophysiology of metaplasia induction. Although none of Christine P. Petersen, Jason C. Mills, James R. Goldenring +2 moredoaj +1 more sourceRole for Complement C5 in Eosinophilic Inflammation of Severe Asthma
Allergy, EarlyView.Complement activation module, particularly C5, is positively associated with eosinophilic inflammation in severe asthma cohorts. Elevated C5 expression correlates with poor lung function improvement and persistent eosinophilic inflammation. Mouse model studies confirm that C5 exacerbates eosinophilic inflammation, highlighting its potential as a ...Cong Dong, Shaohua Lu, Zhenan Deng, Xuliang Cai, Huahao Shen, Guochao Shi, Changxing Ou, Zuofu Peng, Wei Jiang, Xiuhua Fu, Changzheng Wang, Meiling Jin, Zhongmin Qiu, Xiaoyang Wei, Wei Gu, Kewu Huang, Qiang Li, Xiangyan Zhang, Nanshan Zhong, Kian Fan Chung, Qingling Zhang, on behalf of C‐BIOPRED Consortium, Jiangtao Lin, Yongming Zhang, Nan Su, Xiaoyan Zhang, Qing Zhao, Ying Nong, Ping Chen, Tianyi Zhu, Binbin Ji, Yan Wang, Haitao Zhao, Jinbao Wang, Zhiyuan Zhang, Xiaona Yang, Chunhua Wei, Jing Han, Nong Yu, Qiang Li, Zhifu Yang, Yanhong Liu, Guohua Li, Huadong Guan, Shuping Zhang, Xiuhua Fu, Lihong Wang, Lingxin Meng, Zhenting Sun, Guangqin Cao, Lei Zhao, Kewu Huang, Hong Zhang, Wen Wang, Li An, Yangyu Chen, Yanli Gao, Xiaoxia Liu, Huifen Zhai, Fang Lin, Zhaohui Zhong, Zhongguang Wen, Yan Xiao, Jian Kang, Linfei Kong, Xinming Su, Xue Yan, Dijia Zhou, Huaping Tang, Wei Han, Yi Shu, Tintian Li, Lixin Xie, Hong Hu, Bo Liu, Yuzhu Li, Longmei Fan, Yue Zhang, Shifeng Zhao, Xiaofang Liu, Yuhong Wang, Xichun Zhang, Xinmao Wang, Pen Bai, Guangfa Wang, Yan Hu, Zhanwei Hu, Ju Cao, Bei He, Rui Wu, Xiaoyan Gai, Hong Zhu, Zhihai Han, Jiyi Meng, Wei Chen, Li Ma, Zhenqian Liu, Chunyang Zhang, Yan Zhang, Huahao Shen, Fugui Yan, Bin Shen, Xinghong Wang, Hao Zhang, Yinghua Yin, Jinkai Liu, Yanxiong Mao, Mao Huang, Xin Yao, Mao Huang, Ji Zhou, Zhenzhen Wu, Ping Yan, Yujie Zhang, Xinling Yang, Ningfei Ji, Fan Fei, Wanzhen Fu, Yi Yang, Yuting Shi, Wangjian Cha, Guochao Shi, Min Zhou, Wei Tang, Wei Chen, Jun Zhou, Wenjie Yang, Lei Zhu, Meiling Jin, Liping Xue, Li Li, Chun Li, Yin Gong, Qiang Li, Guogang Xie, Luhong Bao, Wuping Bao, Nianyun Li, Fengming Ding, Min Zhang, Zhongmin Qiu, Li Yu, Jungang Xie, Lingling Yi, Xianghuai Xu, Qiang Chen, Junjun Tang, Jinfu Xu, Xiaobing Ji, Jingyun Shi, Bo Su, Xiaojun Yang, Jiuwen Bai, Shuo Liang, Kebing Cheng, Wei Gu, Jiyong Ma, Yun Liu, Jun Ren, Shan Mao, Qingling Zhang, Baoqing Sun, Jiaxing Xie, Rihuang Qiu, Zhiqiang Wang, Peiyan Zhen, Wenting Luo, Changgao Zhong, Wei Luo, Yanqing Xie, Xinxin Yu, Wenting Yu, Wei He, Changzheng Wang, Qianli Ma, Min Wan, Mingzhou Zhang, Haining Li, Shaoxi Cai, Haijin Zhao, Yanmei Ye, Fang Zhou, Laiyu Liu, Guohua Huang, Jianpeng Liang, Jianping Zhao, Jungang Xie, Qiongjie Hu, Kaiyan Li, Wang Ni, Guohua Zheng, Weining Xiong, Lingling Yi, Xihu Du, Yunhui Zhang, Zhi Li, Xiaoqiong Tan, Feng Liao, Shenglan Wang, Yijiang Huang, Xinjun Cai, Kai Liu, Shaojing Sheng, Yihui Fu, Shenghua Sun, Qiang Zhang, Jinweng Cai, Ye Ling, Pin Chen, Hong Luo, Lv Liu, Zhijun Liu, Yuling Tang, Yusheng Yan, Guiyan Mo, Long Wen, Yinqun Zhu, Du Fan +217 morewiley +1 more sourceAcetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps
Allergy, EarlyView.This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.Bowen Zheng, Tao Lu, Ji Wang, Yalan Zhang, Panhui Xiong, Jieyu Zeng, Shuman Li, Yu Jiang, Yijun Liu, Longlan Shu, Yuan Chen, Yin Zhou, Yue Gu, Dayu Guan, Chenxi Li, Lei Zhao, Shujin Wang, Jie Liu, Xia Ke, Yang Shen, Yucheng Yang +20 morewiley +1 more sourcehTERT, MYC and TP53 deregulation in gastric preneoplastic lesions
BMC Gastroenterology, 2012 Background Gastric cancer is a serious public health problem in Northern Brazil and in the world due to its high incidence and mortality. Despite the severity of the disease, more research is needed to better understand the molecular events involved in ...Silva Tanielly Cristina, Leal Mariana, Calcagno Danielle, de Souza Carolina Rosal, Khayat André, dos Santos Ney Pereira, Montenegro Raquel, Rabenhorst Silvia Helena, Nascimento Mayara, Assumpção Paulo, de Arruda Cardoso Smith Marília, Burbano Rommel +11 moredoaj +1 more sourceThe OLGIMA system for gastric cancer risk assessment. A useful method based on the histological Sydney consensus
Histopathology, EarlyView.The new OLGIMA method for histological gastric cancer risk assessment is based on the severity of glandular atrophy and intestinal metaplasia, in both antrum and corpus, according to the Updated Sydney classification. The highest score of either atrophy or intestinal metaplasia from each location will be used for the final OLGIMA stage.Pedro Genaro Delgado Guillena, Miriam Cuatrecasas, Sheyla Montori, Nayra Felipez Varela, Joan Llach, Iva Archilla, Pablo Florez‐Diez, Eva Barreiro‐Alonso, Javier Tejedor‐Tejada, Raquel Vicente, M Teresa Soria, Alaín Huerta, Silvia Patricia Ortega, Henar Nuñez, Oliver Patrón, Carolina Mangas, Diana Zaffalon, Luis Hernández, Luis Enrique Yip, Gadea Hontoria, Gonzalo Hijos, Maria Jose Domper‐Arnal, Sara Zarraquiños, Alberto Herreros De Tejada, Alicia Córdoba, Anabella Cuestas, Glòria Fernández‐Esparrach, Leticia Moreira, Eduardo Albéniz, on behalf of EpiGASTRIC/EDGAR Consortium, Joan Llach, Sheyla Montori, Anabella Cuestas, Gloria Fernandez‐Esparrach, Nayra Felipez Varela, Fermín Estremera‐Arevalo, Marta Gómez Alonso, Juan José Vila Costas, Victoria Busto Bea, Juan Carrascosa Gil, Vanesa Jusué Irurita, Alicia Córdoba Iturriagagoitia, Concepción Llanos Chavarri, Irene Amat Villegas, Gregorio Aisa Rivera, Irene Fernández de los Reyes, Gina de Lima Piña, Miguel Ángel Resano, Adriana Yague Hernando, Cristina Caballero Martínez, Alfredo López Cousillas, Miriam Cuatrecasas, Pedro Genaro Delgado Guillena, Javier Tejedor, Elena Arruebo, Silvia Patricia Ortega, Henar Nuñez, Pilar Diez, Diana Zaffalon, Luis Hernández, Gadea Hontoria, Rosa Maria Saíz, Gonzalo Hijos, María Jose Domper, Sara Zarraquiños, Astrid Irene, Alberto Herreros, Diego de Frutos, Fatima Valentin, Jose Santiago, Virginia Piñol, Adelina García, Alicia Martín‐Lagos, Pablo Florez, Eva Barreiro, Adolfo Suarez, Raquel Vicente, M Teresa Soria, Cristina Polo, Carmen Yagüe, Alain Huerta, Oliver Patrón, David Tello, Carolina Mangas, Eva Serrano, Juan Martínez, Rodrigo Jover, Raquel Grajal, Luis Enrique Yip, Patricia Gonçalves, Jenifer Muñoz, Cristina Herrera‐Pariente, Laia Bonjoch, Sergi Castellví‐Bel, Dulce Momblan, Tamara Saurí, Irina Luzko, Elisa Cantú‐Germano, Angels Gines, Ignasi Elizalde, Francesc Balaguer, Angelez Perez‐Aisa, Jennifer Hinojosa, Coral Tejido, Laura Rivas, María Francisco, Manu Puga, Franco Baiocchi, Cristina Alejandra Sánchez, Alba Pereiros, Joaquin Cubiella, Alejandro Ledo, Ma Victoria Alvarez, Marta Garzón, Juan Manuel Martín, Salvador Sobrino, Ana García‐Rodríguez, Ines Gil, Alazne Aguirre, Ainara Maiz, Ines Ariño, María Dolores Pico, Beatriz de Riba, Goretti Hernández, Eduardo Albéniz, Leticia Moreira +125 morewiley +1 more sourceEvaluating Cost‐Effectiveness of 85 Endoscopic Surveillance Strategies of Nondysplastic Barrett's Esophagus
Journal of Gastroenterology and Hepatology, EarlyView.ABSTRACT Background
Barrett's esophagus is the known precursor to esophageal adenocarcinoma (EAC), a cancer with poor prognosis. While endoscopic surveillance detects early dysplasia and prevents progression, most Barrett's esophagus patients do not progress to EAC, leading to invasive and costly surveillance.Ravi Vissapragada, Norma B. Bulamu, Roger Yazbeck, Tomonori Aoki, Tim Bright, David I. Watson, Jonathan Karnon +6 morewiley +1 more source
