Results 91 to 100 of about 9,066 (204)
Synaptic consolidation across multiple timescales
Frontiers in Systems Neuroscience, 2014 The brain is bombarded with a continuous stream of sensory events, but retains only a small subset in memory. The selectivity of memory formation prevents our memory from being overloaded with irrelevant items that would rapidly bring the brain to its ...
Lorric Ziegler
doaj +1 more source
Mineralocorticoid receptor blockade during a rat's first violent encounter inhibits its subsequent propensity for violence. [PDF]
, 2013 In individuals naive to serious conflict in an unfamiliar environment, violence has long-lasting effects on subsequent aggressive behavior. This effect of the stressful experience of a first violent conflict occurs in victims as well as offenders.
Haller, József +3 more
core +1 more source
Cancer Medicine, Volume 14, Issue 23, December 2025.ABSTRACT Background Immunostimulatory effects of PARP inhibitors could increase sensitivity to immune checkpoint inhibitors. The previous Phase II trial (MEDIOLA) reported clinical benefits of durvalumab and olaparib (D + O) in patients with germline BRCA‐mutated (gBRCAm) HER2‐negative metastatic breast cancer.
Takeo Fujii +13 more
wiley +1 more source
Short-term plasticity as cause-effect hypothesis testing in distal reward learning [PDF]
, 2014 Asynchrony, overlaps and delays in sensory-motor signals introduce ambiguity as to which stimuli, actions, and rewards are causally related. Only the repetition of reward episodes helps distinguish true cause-effect relationships from coincidental ...
Soltoggio, Andrea
core +2 more sources
Clinical and Translational Discovery, Volume 5, Issue 6, December 2025.Gastric precancerous lesions undergo dynamic epigenetic alterations—including DNA methylation, 5‐hydroxymethylcytosine, non‐coding RNAs, and RNA editing—throughout the Correa's cascade. The integration of these multi‐omics epigenetic signatures facilitates non‐invasive risk stratification, which guides personalised surveillance strategy and targeted ...
Kewei Ma +4 more
wiley +1 more source
A Model of Fast Hebbian Spike Latency Normalization
Frontiers in Computational Neuroscience, 2017 Hebbian changes of excitatory synapses are driven by and enhance correlations between pre- and postsynaptic neuronal activations, forming a positive feedback loop that can lead to instability in simulated neural networks.
Hafsteinn Einarsson +4 more
doaj +1 more source
Materiality and human cognition [PDF]
, 2019 In this paper, we examine the role of materiality in human cognition. We address issues such as the ways in which brain functions may change in response to interactions with material forms, the attributes of material forms that may cause change in brain ...
Overmann, Karenleigh, Wynn, Thomas
core
Collagenous gastritis: clinical features, histologic correlates and unanswered questions
Histopathology, Volume 87, Issue 6, Page 789-801, December 2025.This study provides a comprehensive overview of collagenous gastritis, offering pathologists an updated perspective that is valuable for clinical practice and guiding future research, as well as supporting the development of standardized reporting procedures.
Jiannan Li, Kevin Tanager, Namrata Setia
wiley +1 more source
Frontiers in Psychology, 2015 Stress induces several temporally-guided waves of psychobiological responses that differentially influence learning and memory. One way to understand how the temporal dynamics of stress influence these cognitive processes is to consider stress, itself ...
Chelsea E Cadle, Phillip R Zoladz
doaj +1 more source
Histopathology, Volume 87, Issue 6, Page 904-914, December 2025.Breast acinar cell carcinoma (AciCC) comprises two subtypes: (1) ‘Carcinoma with acinar cell differentiation’ (Figure A, NR4A3‐negative, meeting WHO criteria) and (2) true salivary gland‐type AciCC (Figure B, NR4A3‐positive or rearrangement). Integrated morphological‐molecular profiling resolves diagnostic controversies, redefining classification and ...
Mingfang Sun +5 more
wiley +1 more source