Results 91 to 100 of about 15,121 (239)

Immune Checkpoint Inhibitors and Liver Transplantation: Case Report and Review of the Literature

Clinical Case Reports, Volume 13, Issue 4, April 2025.
ABSTRACT As immunotherapy is becoming more inevitable in everyday oncology, we are witnessing a higher number of patients who are on immunosuppressive medication but are also candidates for immune checkpoint inhibitors (ICIs) treatment. There have been few case reports and several small retrospective studies investigating the use of ICIs in liver ...
Iva Skocilic, Alojzije Kosic, Ivona Badovinac, Tajana Filipec Kanizaj, Renata Dobrila Dintinjana, Maja Kolak, Anamarija Bukovica, Sanja Ropac, Ivana Mikolasevic   +8 more
wiley   +1 more source

Poor Performance of Applicator Tampon‐Based Self‐Collection for Liquid‐Based Cytology Among Women Attending a Tertiary Hospital in South Africa

Diagnostic Cytopathology, Volume 53, Issue 4, Page 150-160, April 2025.
ABSTRACT Background The South African Cervical Cancer Prevention and Control Policy was updated in June 2017, recommending liquid‐based cytology (LBC) as the preferred screening method and the investigation of self‐sampling for cervical cancer screening.
Teboho Amelia Tiiti, Varsetile Varster Nkwinika, Tebogo Loraine Mashishi, Kgotlaethata Aaron Molefi, Thembeni Lucia Msibi, Moshawa Khaba, Johannes Bogers, Ramokone Lisbeth Lebelo   +7 more
wiley   +1 more source

Cortical Circuits from Scratch: A Metaplastic Architecture for the Emergence of Lognormal Firing Rates and Realistic Topology [PDF]

arXiv, 2017
Our current understanding of neuroplasticity paints a picture of a complex interconnected system of dependent processes which shape cortical structure so as to produce an efficient information processing system. Indeed, the cooperation of these processes is associated with robust, stable, adaptable networks with characteristic features of activity and ...
arxiv  

Mechanisms of Homeostatic Synaptic Plasticity in vivo

Frontiers in Cellular Neuroscience, 2019
Synapses undergo rapid activity-dependent plasticity to store information, which when left uncompensated can lead to destabilization of neural function.
Hey-Kyoung Lee, Hey-Kyoung Lee, Alfredo Kirkwood   +2 more
doaj   +1 more source

Contextual Fear Extinction Induces Hippocampal Metaplasticity Mediated by Metabotropic Glutamate Receptor 5

Cerebral Cortex, 2018
Dysregulated fear memory can lead to a broad spectrum of anxiety disorders. The brain systems underlying fear memory are manifold, with the hippocampus being prominently involved by housing fear-related spatial memories as engrams, which are created and ...
Branden J. Stansley, Nicole M. Fisher, Rocco G. Gogliotti, C. Lindsley, P. Conn, C. Niswender   +5 more
semanticscholar   +1 more source

Proliferative Markers in Breast Cancer and Chemotherapy Implications: A Comprehensive Review

Health Science Reports, Volume 8, Issue 4, April 2025.
ABSTRACT Background and Aims Breast cancer is the most common cancer and a leading cause of cancer‐related death among women globally. Determining which patients will benefit from chemotherapy remains challenging. Proliferative markers such as Ki‐67, mini chromosome maintenance (MCM) proteins, and proliferating cell nuclear antigen (PCNA) offer ...
Aryan Salahi‐Niri, Paniz Zarand, Fatemeh Shojaeian, Negar Mansouri, Omid Yazdani, Romina Esbati, Seyed Amir Ahmad Safavi‐Naini, Behnaz Jahanbin   +7 more
wiley   +1 more source

Hydrosalpinx treatment before in‐vitro fertilization: systematic review and network meta‐analysis

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 4, Page 414-426, April 2025.
ABSTRACT Objective To compare the safety and effectiveness of different methods, both ablative and non‐ablative, to treat hydrosalpinx in infertile patients before in‐vitro fertilization embryo transfer (IVF‐ET) via a systematic review and network meta‐analysis (NMA).
F. Pérez‐Milán, M. Caballero‐Campo, M. Carrera‐Roig, E. Moratalla‐Bartolomé, J. A. Domínguez‐Arroyo, J. L. Alcázar‐Zambrano, L. Alonso‐Pacheco, J. A. Carugno, on behalf of the Spanish Fertility Society Special Interest Group on Organic Reproductive Disorders   +8 more
wiley   +1 more source

Untersuchungen zur Modellierung und Schaltungsrealisierung von synaptischer Plastizitaet [PDF]

arXiv, 2014
This manuscript deals with the analysis and VLSI implementation of adaptive information processing derived from biological measurements. Specifically, models for short term plasticity, long term plasticity and metaplasticity are derived from biological measurements and implemented in CMOS circuits.
arxiv  

Metaplasticity mechanisms restore plasticity and associativity in an animal model of Alzheimer’s disease

Proceedings of the National Academy of Sciences of the United States of America, 2017
Significance Under physiological conditions, metaplasticity is ideally suited to prepare neuronal networks for encoding specific information, thereby ensuring subsequent learning and long-lasting memory storage.
Qin Li, Sheeja Navakkode, M. Rothkegel, T. Soong, Sreedharan Sajikumar, M. Korte   +5 more
semanticscholar   +1 more source

Faecal Microbiota Transplantation Modulates Morphine Addictive‐Like Behaviours Through Hippocampal Metaplasticity

Addiction Biology, Volume 30, Issue 4, April 2025.
Behavioral features of addiction, such as dependence and tolerance to the analgesic effects of morphine and changes in synaptic plasticity in the hippocampus, can be influenced by alterations in the gut microbiota population and the fecal microbiota transplantation process.
Negin Saeedi, Fereshteh Pourabdolhossein, Masoud Dadashi, Ali Jaafari Suha, Mahyar Janahmadi, Gila Behzadi, Narges Hosseinmardi   +6 more
wiley   +1 more source