Results 101 to 110 of about 9,287 (251)
Stress induces several temporally-guided waves of psychobiological responses that differentially influence learning and memory. One way to understand how the temporal dynamics of stress influence these cognitive processes is to consider stress, itself ...
Chelsea E Cadle, Phillip R Zoladz
doaj +1 more source
Partial Response After Toripalimab Plus Anlotinib for Advanced Metaplastic Breast Carcinoma: A Case Report [PDF]
Yang Fu, Jie Liu, Yu Jiang
openalex +1 more source
ABSTRACT Background Atypical glandular cells (AGC) in cervical cytology, as defined by the Bethesda System, indicate nuclear atypia beyond reactive changes but without definitive features of malignancy. Although clinically significant because it prompts follow‐up procedures, no quantitative threshold exists for AGC diagnosis.
Havva Gokce Terzioglu +2 more
wiley +1 more source
Complete Response of Triple-Negative Metaplastic Carcinoma of the Breast Using Pembrolizumab
Amrita Ladwa +5 more
openalex +1 more source
Inflammation and Cancer: Molecular Mechanisms and Therapeutic Targets
Chronic inflammation fuels tumorigenesis via “internal drivers” and “external attractions.” Targeting these core mechanisms with combined therapies/novel deliveries enables precise, potent anti‐inflammatory–antitumor treatment. ABSTRACT Inflammation is a core pathological factor regulating tumor initiation, progression, and therapeutic resistance, and ...
Xiaodie Liu +4 more
wiley +1 more source
Synaptic consolidation across multiple timescales
The brain is bombarded with a continuous stream of sensory events, but retains only a small subset in memory. The selectivity of memory formation prevents our memory from being overloaded with irrelevant items that would rapidly bring the brain to its ...
Lorric Ziegler
doaj +1 more source
Activation of dopamine receptor D1 (D1R) stimulates PKA and ERK pathways via dissociation of stimulatory and olfactory G protein alpha subunits (Gαs/olf). PKA relieves striatal‐enriched protein tyrosine phosphatase (STEP) inhibition of ERK, promoting cyclic adenosine monophosphate response element‐binding protein (CREB)‐driven transcription of ...
Kevin Chua +2 more
wiley +1 more source
Esophageal adenocarcinoma (EAC) often develops from gastroesophageal reflux disease (GERD), with Barrett's esophagus (BE) as its main precursor. While proton pump inhibitors manage GERD symptoms, their preventive role in EAC remains unclear. This review summarizes advances in diagnosing BE and evaluates anti‐reflux surgery for its potential to prevent ...
Dagmar Kollmann +12 more
wiley +1 more source
Temperoammonic stimulation depotentiates Schaffer collateral LTP via p38 MAPK downstream of adenosine A1 receptors [PDF]
We previously found that low-frequency stimulation of direct temperoammonic (TA) inputs to hippocampal area CA1 depotentiates previously established long-term potentiation in the Schaffer collateral (SC) pathway through complex signaling involving ...
Izumi, Yukitoshi, Zorumski, Charles F
core +1 more source

