Results 31 to 40 of about 15,121 (239)
Nature Communications, 2020 GABAA/glycine-mediated neuronal inhibition critically depends on intracellular chloride (Cl−) concentration which is mainly regulated by the K+-Cl− co-transporter 2 (KCC2) in the adult central nervous system (CNS).
F. Ferrini +12 more
semanticscholar +1 more source
All-trans retinoic acid induces synaptopodin-dependent metaplasticity in mouse dentate granule cells
bioRxiv, 2021 The vitamin A derivative all-trans retinoic acid (atRA) is a key mediator of synaptic plasticity. Depending on the brain region studied, distinct effects of atRA on excitatory and inhibitory neurotransmission have been reported.
M. Lenz +6 more
semanticscholar +1 more source
Metaplastic and Energy-Efficient Biocompatible Graphene Artificial Synaptic Transistors for Enhanced Accuracy Neuromorphic Computing [PDF]
, 2022 CMOS-based computing systems that employ the von Neumann architecture are relatively limited when it comes to parallel data storage and processing. In contrast, the human brain is a living computational signal processing unit that operates with extreme parallelism and energy efficiency.
arxiv +1 more source
Advances in Materials, 2018 Emulation of brain‐like signal processing with thin‐film devices can lay the foundation for building artificially intelligent learning circuitry in future.
R. John +8 more
semanticscholar +1 more source
Frontiers in Synaptic Neuroscience, 2010 Fragile X Syndrome (FXS) is the most common heritable cause of intellectual disability. In vitro electrophysiologic data from mouse models of FXS suggest that loss of Fragile X Mental Retardation Protein (FMRP) affects intracortical excitability and ...
Lindsay M Oberman +10 more
doaj +1 more source
Social Transmission and Buffering of Hippocampal Metaplasticity after Stress in Mice
Journal of Neuroscience, 2020 In social animals, the behavioral and hormonal responses to stress can be transmitted from one individual to another through a social transmission process, and, conversely, social support ameliorates stress responses, a phenomenon referred to as social ...
I-Chen Lee +3 more
semanticscholar +1 more source
Frontiers in Human Neuroscience, 2021 The potential benefits of priming intermittent theta burst stimulation (iTBS) with continuous theta burst stimulation (cTBS) have not been examined in regard to sensorimotor oscillatory activities recorded in electroencephalography (EEG).
Jack Jiaqi Zhang, Kenneth N. K. Fong
doaj +1 more source
Synaptic metaplasticity underlies tetanic potentiation in Lymnaea: a novel paradigm [PDF]
PLoS ONE 8(10): e78056 (2013), 2013 We present a mathematical model which explains and interprets a novel form of short-term potentiation, which was found to be use-, but not time-dependent, in experiments done on Lymnaea neurons. The high degree of potentiation is explained using a model of synaptic metaplasticity, while the use-dependence (which is critically reliant on the presence of
arxiv +1 more source
Plasticity in the Prefrontal Cortex of Adult Rats
Frontiers in Cellular Neuroscience, 2015 We review the plastic changes of the prefrontal cortex of the rat in response to a wide range of experiences including sensory and motor experience, gonadal hormones, psychoactive drugs, learning tasks, stress, social experience, metaplastic experiences,
Bryan eKolb, Robbin eGibb
doaj +1 more source
Bayesian Metaplasticity from Synaptic Uncertainty [PDF]
arXiv, 2023 Catastrophic forgetting remains a challenge for neural networks, especially in lifelong learning scenarios. In this study, we introduce MEtaplasticity from Synaptic Uncertainty (MESU), inspired by metaplasticity and Bayesian inference principles.
arxiv