Results 71 to 80 of about 9,066 (204)

D1/D5 receptor activation promotes long‐term potentiation and synaptic tagging/capture in hippocampal area CA2

open access: yesThe FEBS Journal, EarlyView.
Activation of dopamine receptor D1 (D1R) stimulates PKA and ERK pathways via dissociation of stimulatory and olfactory G protein alpha subunits (Gαs/olf). PKA relieves striatal‐enriched protein tyrosine phosphatase (STEP) inhibition of ERK, promoting cyclic adenosine monophosphate response element‐binding protein (CREB)‐driven transcription of ...
Kevin Chua   +2 more
wiley   +1 more source

Glucocorticoid receptor-mediated amygdalar metaplasticity underlies adaptive modulation of fear memory by stress

open access: yeseLife, 2018
Glucocorticoid receptor (GR) is crucial for signaling mediated by stress-induced high levels of glucocorticoids. The lateral nucleus of the amygdala (LA) is a key structure underlying auditory-cued fear conditioning.
Ran Inoue   +6 more
doaj   +1 more source

Data mining for the diagnosis of type 2 diabetes [PDF]

open access: yes, 2012
Diabetes is the most common disease nowadays in all populations and in all age groups. diabetes contributing to heart disease, increases the risks of developing kidney disease, blindness, nerve damage, and blood vessel damage.
Andina de la Fuente, Diego   +1 more
core  

Neurotransmitters Drive Combinatorial Multistate Postsynaptic Density Networks [PDF]

open access: yes, 2009
The mammalian postsynaptic density (PSD) comprises a complex collection of ~1100 proteins. Despite extensive knowledge of individual proteins, the overall organization of the PSD is poorly understood.
Choudhary, Jyoti S   +8 more
core   +1 more source

Case Report: A Metaplastic Like Triple Negative Breast Cancer with Good Prognosis Histological Subtype [PDF]

open access: diamond, 2023
Adrien Tissié   +5 more
openalex   +1 more source

Immunohistochemical characterization of peritoneal inclusion cysts with squamous metaplasia

open access: yesHistopathology, EarlyView.
Aims Peritoneal inclusion cysts (PICs) are mesothelial‐lined cysts that can uncommonly develop squamous metaplasia. Here, we describe the immunophenotype of PICs with squamous metaplasia using a comprehensive immunohistochemical (IHC) panel. Methods and results We collected surgical excisions of PICs with squamous metaplasia from our institution and ...
Heather I Chen‐Yost   +6 more
wiley   +1 more source

Possible Modulation of the Amygdala on Metaplasticity Deficits in the Hippocampal CA1 Field in Early Postnatally Stressed Rats

open access: yesJournal of Pharmacological Sciences, 2012
Several lines of evidence have shown that early life experiences have a profound impact on fear-related behavior, but the detailed mechanisms are unknown.
Sachiko Hiraide   +8 more
doaj   +1 more source

The big picture: Mary Dallman, a role model

open access: yesStress, 2023
Mary Dallman has left a legacy in neuroendocrinology, not only as the scientist who elaborated on new concepts such as rapid corticosteroid feedback pathways, but also as a role model, particularly for women who followed in her footsteps.
Marian Joëls
doaj   +1 more source

Optogenetic stimulation of the median preoptic nucleus: Effects on hypothalamic paraventricular nucleus magnocellular neurons after chronic intermittent hypoxia exposure

open access: yesJournal of Neuroendocrinology, EarlyView.
Abstract Median preoptic nucleus (MnPO) neurons projecting to the hypothalamic paraventricular nucleus (PVN) are linked to hypertension induced by chronic intermittent hypoxia (CIH), a model of obstructive sleep apnea. The modulation of MnPO‐driven synaptic activity in PVN magnocellular neurons (MNCs) by CIH remains unexamined.
Obed T. Paundralingga   +4 more
wiley   +1 more source

NMDA receptor-dependent metaplasticity by high-frequency magnetic stimulation [PDF]

open access: yes, 2014
High-frequency magnetic stimulation (HFMS) can elicit N-methyl-D-aspartate (NMDA) receptor-dependent long-termpotentiation (LTP) at Schaffer collateral-CA1 pyramidal cell synapses.
Kirschstein, Timo   +4 more
core  

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