Results 71 to 80 of about 9,066 (204)
Activation of dopamine receptor D1 (D1R) stimulates PKA and ERK pathways via dissociation of stimulatory and olfactory G protein alpha subunits (Gαs/olf). PKA relieves striatal‐enriched protein tyrosine phosphatase (STEP) inhibition of ERK, promoting cyclic adenosine monophosphate response element‐binding protein (CREB)‐driven transcription of ...
Kevin Chua +2 more
wiley +1 more source
Glucocorticoid receptor (GR) is crucial for signaling mediated by stress-induced high levels of glucocorticoids. The lateral nucleus of the amygdala (LA) is a key structure underlying auditory-cued fear conditioning.
Ran Inoue +6 more
doaj +1 more source
Data mining for the diagnosis of type 2 diabetes [PDF]
Diabetes is the most common disease nowadays in all populations and in all age groups. diabetes contributing to heart disease, increases the risks of developing kidney disease, blindness, nerve damage, and blood vessel damage.
Andina de la Fuente, Diego +1 more
core
Neurotransmitters Drive Combinatorial Multistate Postsynaptic Density Networks [PDF]
The mammalian postsynaptic density (PSD) comprises a complex collection of ~1100 proteins. Despite extensive knowledge of individual proteins, the overall organization of the PSD is poorly understood.
Choudhary, Jyoti S +8 more
core +1 more source
Case Report: A Metaplastic Like Triple Negative Breast Cancer with Good Prognosis Histological Subtype [PDF]
Adrien Tissié +5 more
openalex +1 more source
Immunohistochemical characterization of peritoneal inclusion cysts with squamous metaplasia
Aims Peritoneal inclusion cysts (PICs) are mesothelial‐lined cysts that can uncommonly develop squamous metaplasia. Here, we describe the immunophenotype of PICs with squamous metaplasia using a comprehensive immunohistochemical (IHC) panel. Methods and results We collected surgical excisions of PICs with squamous metaplasia from our institution and ...
Heather I Chen‐Yost +6 more
wiley +1 more source
Several lines of evidence have shown that early life experiences have a profound impact on fear-related behavior, but the detailed mechanisms are unknown.
Sachiko Hiraide +8 more
doaj +1 more source
The big picture: Mary Dallman, a role model
Mary Dallman has left a legacy in neuroendocrinology, not only as the scientist who elaborated on new concepts such as rapid corticosteroid feedback pathways, but also as a role model, particularly for women who followed in her footsteps.
Marian Joëls
doaj +1 more source
Abstract Median preoptic nucleus (MnPO) neurons projecting to the hypothalamic paraventricular nucleus (PVN) are linked to hypertension induced by chronic intermittent hypoxia (CIH), a model of obstructive sleep apnea. The modulation of MnPO‐driven synaptic activity in PVN magnocellular neurons (MNCs) by CIH remains unexamined.
Obed T. Paundralingga +4 more
wiley +1 more source
NMDA receptor-dependent metaplasticity by high-frequency magnetic stimulation [PDF]
High-frequency magnetic stimulation (HFMS) can elicit N-methyl-D-aspartate (NMDA) receptor-dependent long-termpotentiation (LTP) at Schaffer collateral-CA1 pyramidal cell synapses.
Kirschstein, Timo +4 more
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