Where next for partial randomisation of research funding? The feasibility of RCTs and alternatives [version 2; peer review: 2 approved, 1 approved with reservations] [PDF]
Wellcome Open Research, 2023 We outline essential considerations for any study of partial randomisation of research funding, and consider scenarios in which randomised controlled trials (RCTs) would be feasible and appropriate.
Tom Stafford +6 more
doaj +2 more sources
Dissemination of Registered COVID-19 Clinical Trials (DIRECCT): a cross-sectional study. [PDF]
BMC Med, 2023 Background The results of clinical trials should be completely and rapidly reported during public health emergencies such as COVID-19. This study aimed to examine when, and where, the results of COVID-19 clinical trials were disseminated throughout the ...
Salholz-Hillel M +9 more
europepmc +3 more sources
Resource use and costs of investigator-sponsored randomized clinical trials in Switzerland, Germany, and the United Kingdom: a metaresearch study [PDF]
Journal of Clinical EpidemiologyBACKGROUND AND OBJECTIVES Conducting high-quality randomized clinical trials (RCTs) is challenging and resource intensive. Funders and academic investigators depend on limited financial resources and, therefore, need empirical data for optimal budget ...
Amstutz, Alain +11 more
core +4 more sources
Is biomedical research self-correcting? Modelling insights on the persistence of spurious science [PDF]
Royal Society Open ScienceThe reality that volumes of published biomedical research are not reproducible is an increasingly recognized problem. Spurious results reduce trustworthiness of reported science, increasing research waste.
David Robert Grimes
doaj +2 more sources
Region of Attainable Redaction, an extension of Ellipse of Insignificance analysis for gauging impacts of data redaction in dichotomous outcome trials [PDF]
eLifeIn biomedical science, it is a reality that many published results do not withstand deeper investigation, and there is growing concern over a replicability crisis in science.
David Robert Grimes
doaj +2 more sources
Nonsignificance misinterpreted as an effect’s absence in psychology: prevalence and temporal analyses [PDF]
Royal Society Open ScienceNonsignificant findings in psychological research are frequently misinterpreted as reflecting the effect’s absence. However, this issue’s exact prevalence remains unclear, as does whether this issue is getting better or worse.
Stephen Lee Murphy +3 more
doaj +2 more sources
Technological advances in preclinical meta-research. [PDF]
BMJ Open Sci, 2021 Bannach-Brown A +5 more
europepmc +4 more sources
Characteristics of search methods in dental meta-research studies: a methodological study
Journal of Clinical EpidemiologyMetaresearch studies, defined as, "research on research," should transparently report search methods used to identify the assessed research. Currently, there is no published evaluation of search methods reporting in metaresearch studies. The aim of this study was to assess the characteristics of search methods in dental meta-research studies and to ...
Clovis Mariano Faggion
exaly +4 more sources
Science of science: A multidisciplinary field studying science. [PDF]
HeliyonScience and knowledge are studied by researchers across many disciplines, examining how they are developed, what their current boundaries are and how we can advance them. By integrating evidence across disparate disciplines, the holistic field of science
Krauss A.
europepmc +3 more sources
The present and future of peer review: Ideas, interventions, and evidence. [PDF]
Proc Natl Acad Sci U S AWhat is wrong with the peer review system? Is peer review sustainable? Useful? What other models exist? These are central yet contentious questions in today’s academic discourse.
Aczel B +12 more
europepmc +3 more sources