Results 191 to 200 of about 823,422 (248)

Integrated cytomembrane proteomics identifies EpCAM/MGST1 as therapeutic targets in metastatic laryngeal carcinoma. [PDF]

Front Genet
Zhuang S, Wu X, Lin X, Li Z, Gan D, Wang S, Lin X, Lin G, Gao M.   +8 more
europepmc   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

Signal metastasis in the radius treated by excision and bone graft.

, 1968
Roger Dee, D R Sweetnam
openalex  

Mechanobiologically Engineered Mimicry of Extracellular Vesicles for Improved Systemic Biodistribution and Anti‐Inflammatory Treatment Efficacy in Rheumatoid Arthritis

Advanced Healthcare Materials, EarlyView.
Triblock copolymer‐reinforced liposomal mimics of extracellular vesicles are engineered with tunable membrane elasticity. A semi‐elastic formulation (Tri‐ARTEX8:2) co‐encapsulating stem cell cytosolic extract and AntagomiR155 targets inflamed joints via the ELVIS effect, reprograms macrophages from M1 to M2, and markedly alleviates collagen‐induced ...
Dahwun Kim, Hwira Baek, Su Yeon Lim, Min Sang Lee, Siyan Lyu, Jihyun Lee, Tun Naw Sut, Marta Gonçalves, Jeong Yi Kang, Joshua A. Jackman, Jin Woong Kim, Ji Hoon Jeong   +11 more
wiley   +1 more source

Preoperative MRI Assessment of Mesorectal Lymph Node Metastasis in Patients with Rectal Cancer: A Retrospective Study. [PDF]

J Anus Rectum Colon
Shigehara F, Kobayashi H, Koizumi A, Takashima J, Yamazaki K, Sugimoto H, Fujimoto D, Miura F.   +7 more
europepmc   +1 more source

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

Advanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz, Paulo Pereira, João Vasco Ferreira   +2 more
wiley   +1 more source

Programmed Aggregation of Lipidated Nitrobenzoselenadiazole as a Photo‐Activatable Pyroptosis Inducer

Advanced Healthcare Materials, EarlyView.
This study presents alkylated nitrobenzoselenadiazole (NBSD) photosensitizers that self‐assemble into programmable aggregates, enabling photo‐triggered pyroptosis and enhanced ROS generation. The lead compound, NBSD‐NOc, exhibits superior photodynamic activity, high cellular uptake, and implantable gel compatibility with pH‐responsive release.
Jong Min An, Hyunyoung Choi, Hyo In Kim, Do‐Yeon Kim, Jahyun Kim, Jinbong Park, Junyang Jung, Na Young Jeong, Dokyoung Kim   +8 more
wiley   +1 more source

Liver metastasis of colorectal cancer: Mechanism and clinical therapy (Review). [PDF]

Oncol Rep
Yang C, Zhao L, Wang C, Ye Y, Shen Z.
europepmc   +1 more source