Results 191 to 200 of about 2,015,361 (384)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Invasive Mucormycosis in a Chronic Lymphocytic Leukemia Patient on Zanubrutinib: A Case Report

Infection and Drug Resistance
Hazrat Bilal,1,* Xiaohui Li,1,* Qiao-Li Lv,1 Hanman Qiu,1 Yu-An Qiu,2 Bin Xu1 1Jiangxi Key Laboratory of Oncology (2024SSY06041), JXHC Key Laboratory of Tumour Metastasis, NHC Key Laboratory of Personalized Diagnosis and Treatment of ...
Bilal H, Li X, Lv QL, Qiu H, Qiu YA, Xu B   +5 more
doaj  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Tumor Metastasis: Molecular Insights and Evolving Paradigms

Cell, 2011
Scott Valastyan, R. Weinberg
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Targeting P2X₇ receptor inhibits the metastasis of murine P388D1 lymphoid neoplasm cells to lymph nodes [PDF]

, 2010
Shuangyi Ren, Yi Zhang, Yujing Wang, Yuejian Lui, Wei Wei, Xiaohua Huang, Wenjuan Mao, Yunfei Zuo   +7 more
openalex   +1 more source

MTSS1 inhibits colorectal cancer metastasis by regulating the CXCR4/CXCL12 signaling axis

, 2021
Lei Chen, Qiang Chen, Yongyou Wu, Minggao Zhu, Jia Hu, Zhixiang Zhuang   +5 more
openalex   +2 more sources

The role of lipids in cancer progression and metastasis.

Cell Metabolism, 2022
M. Martín-Pérez, Uxue Urdiroz-Urricelqui, Claudia Bigas, S. Benitah   +3 more
semanticscholar   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Hepatic Macronodular Tuberculoma Mimics Liver Metastasis in a Patient With Locoregional Advanced Tongue Cancer [PDF]

, 2011
Te‐Chun Hsieh, Yu‐Chin Wu, Cheng-Nan Hsu, Chun‐Fan Yang, I‐Ping Chiang, Ching-Yun Hsieh, Shung‐Shung Sun, Chia‐Hung Kao   +7 more
openalex   +1 more source