MTA1 promotes epithelial to mesenchymal transition and metastasis in non-small-cell lung cancer
, 2017 Ke Ma +13 more
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FEBS Open Bio, EarlyView.Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel +9 more
wiley +1 more source
Machine learning and Shapley Additive exPlanations to predict metastasis of lymph nodes posterior to the recurrent laryngeal nerve in cN0 papillary thyroid carcinoma. [PDF]
Front OncolZhou J +11 more
europepmc +1 more source
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
The impact of macrophage infiltration on [18F]FDG PET accuracy in identifying mediastinal and abdominal lymph node metastases: A retrospective cohort study. [PDF]
PLoS OneWei J, Tao W, Yang T, Dong J.
europepmc +1 more source
Prediction of sentinel lymph node metastasis in breast cancer patients based on preoperative features: a deep machine learning approach [PDF]
Reza Shahriarirad +5 more
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Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
[Cancer metastasis and metastasis suppressors].
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2005 Cancer metastasis, a complex and sequential network of cellular events involved in the migration and establishment of malignant cells from original site to distant foci, is an important and significant contributor to morbidity and mortality of cancer patients. Despite the clinical importance of cancer metastasis, its molecular and biochemical mechanism
openaire +1 more source
Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
FEBS Open Bio, EarlyView.The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source