Results 81 to 90 of about 336,084 (346)

Ethiopathogenic factors influencing the development of basal cell carcinoma

Universidad Médica Pinareña, 2021
Introduction: basal cell carcinoma is a cutaneous neoplasm of high incidence, characterized by slow growth and low metastatic capacity. Objective: to describe the ethiopathogenic factors that influence on the onset of basal cell carcinoma.
Roine Alberto Pena-Olivera, Ana Laura Navarro-Baldellot, Leydiani Espín-Guerra   +2 more
doaj  

Attitudes among dermatologists regarding non-melanoma skin cancer treatment options

Discover Oncology, 2021
Non-melanoma skin cancers include basal and squamous cell carcinoma. These tumors have become an important health issue for their high incidence and for the morbidity, especially if untreated for a long period.
Luca Fania, Tonia Samela, Gaia Moretta, Francesco Ricci, Elena Dellambra, Mara Mancini, Francesca Sampogna, Annarita Panebianco, Damiano Abeni   +8 more
doaj   +1 more source

Basal Cell Carcinoma Metastatic to Parotid Gland [PDF]

Head and Neck Pathology, 2013
Metastasis from basal cell carcinoma of the skin is very rare with cases being documented in the lymph nodes, lung, bone and parotid gland. The main histopathological differential diagnosis is the locally arising basal cell adenocarcinoma from which it is difficult to distinguish by morphology and routine immunohistochemistry. Approximately 85 % of all
Silvana Di Palma, Silvana Di Palma, Rinsey Rose Kurian, A. W. Barrett   +3 more
openaire   +3 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Vismodegib y sonidegib en el carcinoma de células basales localmente avanzado y metastásico: actualización acerca de los inhibidores de la vía de Hedgehog

Actas Dermo-Sifiliográficas, 2022
Resumen: El carcinoma de células basales (CBC) es una de las neoplasias malignas más frecuentes, por lo que se ha convertido en una importante carga asistencial. Su incidencia se incrementa anualmente, especialmente en la población con mayor edad.
J. Kurnia Wijaya, K. Djawad, S. Wahab, A. Nurdin, A. Irawan Anwar   +4 more
doaj  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Heparan sulfate proteoglycans undergo differential expression alterations in left sided colorectal cancer, depending on their metastatic character [PDF]

, 2018
Background Heparan sulfate proteoglycans (HSPGs) are complex molecules which play a role in the invasion and growth and metastatic properties of cancerous cells.
Castañón de la Torre, Sonia, Crespo Susperregui, Ainara, Fernández Vega, Iván, García Fernández, Beatriz, García Suárez, Olivia, Quirós Fernández, Luis Manuel, Solis Hernández, María Pilar   +6 more
core   +2 more sources

A case of basal cell carcinoma of skin with bone metastasis: a case report

Journal of Medical Case Reports
Background Basal cell carcinoma is the most prevalent skin cancer, most characterized by local aggressiveness but with low metastatic potential, and bone metastasis is quite heterogeneous, thus the incidence profile is variable size from 0.0028% to 0.5%.
Azadeh Khayyat, MohammadAli Esmaeil Pour, Hamid Nasrollahi, Mohammad Mehdi Mehrabi, Seyed Amir Zohouri, Bita Geramizadeh   +5 more
doaj   +1 more source

Two Basal Cell Carcinomas of the Axillae: A Metastasis or an Independent Development?

Case Reports in Dermatological Medicine, 2015
Cutaneous basal cell carcinoma (BCC) is a common malignancy amongst the elderly. BCC rarely metastasises, and fewer than 300 cases of metastatic BCC have been reported in the literature.
Yuichiro Endo, Yoshiki Miyachi
doaj   +1 more source