Results 111 to 120 of about 31,387 (227)

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 11, 20 March 2026.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu   +4 more
wiley   +1 more source

BK virus‐associated urothelial carcinoma—A supra‐regional cohort of kidney transplant recipients

open access: yesBJUI Compass, Volume 7, Issue 3, March 2026.
Abstract Objectives This study aims to study the clinical features, pathological findings, and outcomes of BK virus‐associated urothelial carcinoma (UC) in kidney transplant recipients (KTRs). Patients and Methods The study was conducted in a retrospective cohort of KTRs with histologically confirmed UC managed at a UK supra‐regional transplant urology
Noah Beetge   +4 more
wiley   +1 more source

Population pharmacokinetics and exposure–response analysis of durvalumab in patients with resectable stage II to IIIB (N2) NSCLC in the phase III AEGEAN study

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 3, Page 980-996, March 2026.
Aims In the AEGEAN study, perioperative durvalumab plus platinum‐based neoadjuvant chemotherapy for patients with resectable stage II to IIIB (N2) non‐small‐cell lung cancer (NSCLC) demonstrated a favourable benefit–risk profile. This study evaluated population pharmacokinetics (PopPK) and exposure–response (ER) relationships of durvalumab in patients ...
Xiaoying Zhao   +12 more
wiley   +1 more source

Are There Socio‐Demographic Inequalities in the Utilisation of Tumour and ctDNA Somatic Mutation Testing in Solid Tumours? A Systematic Review

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
This systematic review investigates whether inequalities exist in the utilisation of tumour and ctDNA somatic mutation testing in solid tumours. The review concludes that, across tumour types, testing modalities and socio‐demographic factors, inequalities exist and require further exploration.
Sarah Rae   +5 more
wiley   +1 more source

Vitamin D and Bladder Cancer Risk: An Umbrella Review and Second Order Meta‐Analysis

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Introduction Bladder cancer is a common malignancy with a high recurrence rate, posing a significant public health burden. Beyond its role in bone health, vitamin D has been suggested to influence cancer risk, including bladder cancer. Aim To evaluate the association between serum vitamin D levels, dietary intake, and supplementation with ...
Stefano Mancin   +10 more
wiley   +1 more source

Genetic Alterations Involved in Immune Escape Mechanisms of Circulating Tumour Cells in Colorectal Carcinogenesis

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT In colorectal cancer (CRC), circulating tumour cells (CTCs) employ genetic alterations to dodge the body's immune system. These alterations occur in specific “driver” genes, including KRAS, BRAF, p53, MYC, APC and PTEN. Changes in these genes can control how the tumour interacts with the immune system and influence the expression of immune ...
Sharmin Aktar   +5 more
wiley   +1 more source

Urinary Diversion–Specific Morbidity After Radical Cystectomy: A Ten‐Year Institutional Experience

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Introduction This study investigates the correlations and risk factors of complications associated with different urinary diversion methods after radical cystectomy (RC) for bladder cancer (BC). Methods A retrospective analysis was conducted on 574 bc patients treated between 2012 and 2022.
Xuanhan Hu   +8 more
wiley   +1 more source

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