Results 121 to 130 of about 31,387 (227)

Pattern and Clinical Significance of CA19‐9 Expression in Human Cancer: A Tissue Microarray Study on 14,966 Tumors

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Background Carbohydrate antigen 19–9 (CA19‐9) is a cell surface glycoprotein widely used as a diagnostic and prognostic serum marker for monitoring pancreatic cancer. The aim of this study was to evaluate the prevalence and clinical relevance of CA19‐9 expression in human cancer. Methods To comprehensively determine the prevalence and clinical
Nina Schraps   +31 more
wiley   +1 more source

Multi‐omic profiling defines three distinct molecular subtypes of urothelial carcinoma with implications for precision therapy

open access: yesClinical and Translational Medicine, Volume 16, Issue 3, March 2026.
We developed three UC clusters, applicable for MIBC and NMIBC, which were validated using transcriptomic- and proteomic datasets. Publically available UC cell lines were assigned to the clusters, to have in vitro models representing each cluster. The clusters differ in molecular and biological signatures, with distinct prognostic and therapeutic ...
Nils C. H. van Creij   +17 more
wiley   +1 more source

Non‐Functional Paraganglioma of the Urinary Bladder: A Rare Cause of Bladder Tumor

open access: yesIJU Case Reports, Volume 9, Issue 2, March 2026.
ABSTRACT Introduction Paragangliomas of the urinary bladder (PUBs) are rare neuroendocrine tumors, representing less than 0.06% of all bladder neoplasms. While most are functional and associated with catecholamine excess, approximately 15% are non‐functional, often presenting asymptomatically and discovered incidentally.
Matt Wainstein   +4 more
wiley   +1 more source

Anti‐Melanoma Differentiation‐Associated Gene 5 Antibody‐Positive Interstitial Lung Disease, Induced by Enfortumab Vedotin Plus Pembrolizumab for Advanced Urothelial Carcinoma

open access: yesIJU Case Reports, Volume 9, Issue 2, March 2026.
ABSTRACT Introduction Anti‐melanoma differentiation‐associated gene 5 antibody‐positive interstitial lung disease is a rare but fatal adverse event following immune checkpoint inhibitor treatment for cancers. However, such cases have not been previously reported in patients with urothelial carcinoma.
Akira Saito   +4 more
wiley   +1 more source

FGFR Testing in Metastatic Urothelial Carcinoma-Who, When, and How to Test. [PDF]

open access: yesCancers (Basel)
Mansinho A   +7 more
europepmc   +1 more source

A Case of Upper Tract Urothelial Carcinoma With Neuroendocrine Differentiation Successfully Treated With Enfortumab Vedotin and Pembrolizumab

open access: yesIJU Case Reports, Volume 9, Issue 2, March 2026.
ABSTRACT Introduction Upper tract urothelial carcinoma with neuroendocrine differentiation (UC‐NE) is extremely rare and generally associated with aggressive behavior and poor prognosis. Optimal treatment strategies remain unclear, particularly regarding the role of nectin‐4–targeted therapy. Case Presentation A 61‐year‐old man was diagnosed with UC‐NE
Kosei Taniguchi   +9 more
wiley   +1 more source

Early Recognition of Immune‐Related Hepatitis During Avelumab Maintenance Therapy for Urothelial Carcinoma

open access: yesIJU Case Reports, Volume 9, Issue 2, March 2026.
ABSTRACT Introduction Avelumab is recommended as maintenance therapy for advanced urothelial carcinoma after platinum chemotherapy; however, immune‐related adverse events can be severe and refractory. Case Presentation A 79‐year‐old male developed immune‐related hepatitis during avelumab maintenance therapy following gemcitabine plus carboplatin for ...
Yuka Iwama   +9 more
wiley   +1 more source

The prognostic role of the neutrophil-to-lymphocyte ratio in metastatic urothelial carcinoma. [PDF]

open access: yesTher Adv Med Oncol
Balli S   +6 more
europepmc   +1 more source

High‐Grade Urothelial Carcinoma Arising From a Ureteral Diverticulum: A Rare Case Report

open access: yesIJU Case Reports, Volume 9, Issue 2, March 2026.
ABSTRACT Introduction Ureteral diverticula are rare urological anomalies characterized by outpouchings of the ureteral wall. Malignancy arising from these structures is exceptionally rare, with only a few cases reported. Case Presentation We report a 57‐year‐old male with high‐grade urothelial carcinoma arising from a ureteral diverticulum in the left ...
Iason Papadopoulos   +9 more
wiley   +1 more source

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