Sex Differences in Cancer Immunotherapy—Clinical Evidence and Mechanisms With a Focus on NSCLC
ABSTRACT Accumulating evidence suggests that the immune system shows subtle but relevant differences between men and women. These differences may have an impact on cancer development and TME composition as well as responses to and adverse events elicited by immunotherapies.
Eva Krieghoff‐Henning +4 more
wiley +1 more source
Erdafitinib or Erdafitinib Plus Cetrelimab for Patients With Metastatic Urothelial Carcinoma and <i>FGFR</i> Alterations: Final Results From the Phase II NORSE Study. [PDF]
Loriot Y +12 more
europepmc +1 more source
ABSTRACT Peroxiredoxins (PRDXs) are antioxidant enzymes that scavenge hydrogen peroxide and protect cells from reactive oxygen species (ROS). There are six genes encode different types of PRDXs (PRDX1–PRDX6) in humans and most of them are overexpressed in tumours; however, their expression patterns and prognostic value in bladder cancer (BLCA) remain ...
Jarett Wallerson +3 more
wiley +1 more source
Metastatic Urothelial Carcinoma Presenting as Rectal Linitis Plastica: A Rare Case Report. [PDF]
Lee C, Awad N, Kostalas S.
europepmc +1 more source
Micropapillary urothelial carcinoma metastatic to the male breast
Simon F. Roy, Marie‐Christine Guilbert
openaire +2 more sources
ABSTRACT Cancer cells rely on citrate for multiple metabolic processes, suggesting that limiting the availability of extracellular citrate may represent a novel therapeutic strategy. The plasma membrane citrate transporter (pmCiC) has been implicated in the pathogenesis of several cancers before, and its activity can be inhibited by gluconate.
Konstantin Drexler +8 more
wiley +1 more source
Clonal diversity shapes the tumour microenvironment leading to distinct immunotherapy responses in metastatic urothelial carcinoma. [PDF]
Kamatani T +14 more
europepmc +1 more source
Harnessing blue light photobiomodulation for cancer therapy: Evidence from a systematic review
Conventional treatments for various types of cancer are often associated with tumor recurrence and aggressiveness. Photobiomodulation with blue light (BL; 450–470 nm) emerges as a promising alternative with antitumor effects. This systematic review, with 37 in vitro and in vivo studies from 2002 to 2024, revealed that BL reduces cell viability ...
Bárbara Evelyn Santos de Lima +6 more
wiley +1 more source
SGNDV-001: disitamab vedotin with pembrolizumab in HER2-expressing locally advanced or metastatic urothelial carcinoma. [PDF]
Powles TB +13 more
europepmc +1 more source
Serum Symmetric Dimethylarginine as a Predictor of Toxicity of Carboplatin in Dogs
ABSTRACT Glomerular filtration rate (GFR) predicts carboplatin clearance and myelotoxicity in humans and cats. This relationship is unknown in dogs. In canines, elevated serum symmetric dimethylarginine (SDMA) correlates with reduced GFR. This study prospectively evaluated whether dogs with elevated SDMA (> 14 μg/dL) are at increased risk of ...
Alexandra Gareau +3 more
wiley +1 more source

