Results 41 to 50 of about 31,387 (227)

Update on Chemotherapy in the Treatment of Urothelial Carcinoma

The Scientific World Journal, 2011
Urothelial carcinoma is the fifth most common malignancy diagnosed each year in the United States. Neoadjuvant and adjuvant chemotherapy are given to decrease the risk of recurrent or metastatic disease with the more robust clinical data supporting the ...
Carrie Costantini, Frederick Millard
doaj   +1 more source

Skin nodules and proptosis in a case of carcinoma urinary bladder: An unusual presentation

Indian Journal of Urology, 2021
Metastasis to the skin and orbit from bladder cancer is extremely rare. A 76-year-old diabetic male presented with skin nodules and proptosis of the left eye.
Jeni Elizabeth Mathew, Aditya Prakash Sharma, Debajyoti Chatterjee, Sudheer Kumar Devana   +3 more
doaj   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Metastasis of uterine endometrioid carcinoma mimicking upper tract urothelial carcinoma

Urology Case Reports
Accurate diagnosis of upper-tract urothelial carcinoma is difficult when urine cytology and ureteroscopy are inconclusive. A 59-year-old woman had undergone total hysterectomy for uterine endometrioid carcinoma 5 years earlier.
Yuji Fujizuka, Shugo Harashima, Yoshiyuki Miyazawa, Seiji Arai, Nozomi Nakajima, Mai Onose, Sho Watanuki, Takanori Shimizu, Yoshitaka Sekine, Hidekazu Koike, Hayato Ikota, Kazuhiro Suzuki   +11 more
doaj   +1 more source

Metastatic urothelial carcinoma presenting as acute cholecystitis

Urology Annals, 2019
Metastatic involvement of the gallbladder is uncommon. We report a case of an 84-year-old male who presented with acute cholecystitis secondary to metastatic urothelial carcinoma (UC). An 84-year-old man presented with right upper quadrant pain and a positive Murphy's sign on the background of known metastatic UC.
Xing Yao Ling, Jasmina Kevric, Alexandra DuGuesclin, Julie Teague, Marlon Perera, Elizabeth Penington   +5 more
openaire   +3 more sources

FomA‐Containing Outer Membrane Vesicles of Fusobacterium Nucleatum Facilitate Bladder Cancer Lymphatic Metastasis via IL‐6‐Dependent M2b Macrophage Polarization

Advanced Science, EarlyView.
Urinary Fusobacterium nucleatum–derived outer membrane vesicles are shown to promote bladder cancer lymphatic metastasis. The vesicle protein FomA activates TLR2/NF‐κB signaling in tumor cells, induces IL‐6 secretion, and drives M2b macrophage polarization and VEGF‐C–dependent lymphangiogenesis, revealing a microbiota‐driven mechanism linking tumor ...
Wentai Shangguan, Weijia Li, Wenxue Huang, Jilin Wu, Yao Yu, Yiyao Huang, Lin Yang, Ming Xie, Qishen Yang, Jun Zheng, Yuexuan Zhu, Qi Sun, Biao Li, Leqian Li, Zongwei Wang, Jie Zhao, Peng Wu, Bisheng Cheng   +17 more
wiley   +1 more source

Case report: Two cases of leptomeningeal metastases in patients with metastatic urothelial carcinoma treated with enfortumab vedotin

Frontiers in Oncology
BackgroundLeptomeningeal carcinomatosis is an exceptionally rare pattern of metastases in genitourinary cancer, described in less than 0.1% of cases. We report two cases of patients with metastatic urothelial cancer who initially responded to enfortumab ...
Francine Fishbein, Lucia Nappi, Behnoush Mortazavi, Bernhard Eigl   +3 more
doaj   +1 more source

Gata3 immunohistochemical staining is a useful marker for metastatic breast carcinoma in fine needle aspiration specimens

Journal of Cytology, 2018
Aims: The utility of GATA3 immunohistochemistry (IHC) as an aid to the cytological diagnosis of metastatic breast carcinoma in fine needle aspiration (FNA) specimens was investigated.
Paul W Shield, Stephen J Crouch, David J Papadimos, Michael D Walsh   +3 more
doaj   +1 more source

Role of surgical consolidation in metastatic urothelial carcinoma [PDF]

Current Opinion in Urology, 2016
Since the development of systemic combination chemotherapy, postchemotherapy extirpation has been performed in selected patients mainly with locally advanced and/or initially unresectable bladder cancer, and, in very selected patients, surgical consolidation for visceral metastases has also been performed.
Abe, Takashige, Matsumoto, Ryuji, Shinohara, Nobuo   +2 more
openaire   +2 more sources