Results 51 to 60 of about 31,387 (227)

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Status of oncology drugs with a conditional approval: A cross‐sectional comparison of the Food and Drug Administration and Health Canada

British Journal of Clinical Pharmacology, EarlyView.
Aims This study looks at the status of the same drugs conditionally approved by the Food and Drug Administration and Health Canada for the same oncology indication. Methods Lists of oncology drugs with a conditional approval from the Food and Drug Administration and Health Canada were generated and drug pairs with the same indication were matched ...
Joel Lexchin
wiley   +1 more source

Complete remission with immunotherapy: Case report of a patient with metastatic bladder cancer to the humerus

Urology Case Reports, 2020
Bladder cancer is the sixth most common malignancy in the United States. Cisplatin combination regimens are first line therapy for patients with metastatic urothelial bladder cancer who are eligible candidates and no treatments have shown to improve ...
D. Abdelhakam, P.R. Young, M.K. Jain, A. Nassar, J.A. Copland, W. Tan   +5 more
doaj   +1 more source

Cutaneous metastatic seeding as a sequela of nephrostomy catheter placement

Radiology Case Reports, 2021
Urothelial carcinoma and nephrolithiasis are a common cause of obstructive uropathy which can be relieved by percutaneous nephrostomy catheter placement.
Kavya Mirchia, MD, Kanish Mirchia, MD, Ryan Thibodeau, MPH, Abtin Jafroodifar, MD, Atin Goel, MD, Mohammad Jawed, MD   +5 more
doaj   +1 more source

Immunotherapy for urothelial carcinoma: Metastatic disease and beyond [PDF]

Asia-Pacific Journal of Clinical Oncology, 2020
AbstractFor advanced and metastatic urothelial carcinomas (UCs), platinum (preferably cisplatin)‐based chemotherapy has been the standard treatment for many years. However, many patients are ineligible for cisplatin‐based chemotherapy because of poor performance status and/or other age‐related conditions. At the other end of the spectrum, patients with
openaire   +2 more sources

Update on the Treatment of Metastatic Urothelial Carcinoma [PDF]

The Scientific World Journal, 2018
Platinum-based combination chemotherapy has been the standard of care in the first-line treatment of metastatic urothelial carcinoma (mUC). Treatment of metastatic disease following progression on platinum-based regimens has evolved significantly in the last few years.
Nedal Bukhari, Humaid O. Al-Shamsi, Faisal Azam   +2 more
openaire   +3 more sources

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

Interdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang, Shiwen Deng, Fangfang Jin, Jiayao Qu, Xiang Fan, Peng Chen, Xinrong Fan   +6 more
wiley   +1 more source

Long-term survival of a patient with pulmonary metastatic urothelial carcinoma following metastasectomy

Urology Case Reports, 2018
Cisplatin-based systemic chemotherapy is the gold standard for the treatment of patients with metastatic urothelial carcinoma (UC), which is a chemosensitive cancer. However, long-term survival has been deemed disappointing. We describe here a case of UC
Kenichi Hasebe, Taku Naiki, Risa Oda, Toshiki Etani, Keitaro Iida, Yosuke Sugiyama, Satoshi Nozaki, Ryosuke Ando, Noriyasu Kawai, Ryoichi Nakanishi, Takahiro Yasui   +10 more
doaj   +1 more source

Atezolizumab for the treatment of advanced recurrent basal cell carcinoma and urothelial carcinoma of bladder: a case report

Journal of Medical Case Reports, 2022
Background The use of checkpoint inhibitors has become increasingly important in the treatment of different cancers, including advanced muscle-invasive urothelial cancer and even in basal cell carcinoma.
Zsófia Küronya, Tímea Danyi, Tímea Balatoni, Gabriella Liszkay, Erika Tóth, Krisztina Biró, Lajos Géczi   +6 more
doaj   +1 more source

Autophagy Plays a Suppressive Role in Bladder Tumor Formation in an Orthotopic Mouse Model and Bladder Cancer Patient Specimens

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Autophagy plays either a suppressing or promoting role during tumor development. Clarifying the role of autophagy in bladder tumorigenesis both in vitro and in vivo is crucial for developing novel therapeutic strategies through manipulating autophagy activity.
Wan‐Ting Kuo, Chin‐Chen Pan, Yi‐Wen Liu, Nan‐Haw Chow, Hong‐Lin Cheng, Shan‐Ying Wu, Sheng‐Hui Lan, Chih‐Peng Chang, Hsiao‐Sheng Liu   +8 more
wiley   +1 more source