Results 201 to 210 of about 6,051 (258)

Metered dose inhalers: A need for dose counters

Respirology, 2005
Objectives:  This study investigated the ability of patients to assess when a metered dose inhaler (MDI) is empty.Methodology:  A total of 17 patients assessed, by shaking, the number of doses remaining in a salbutamol MDI that had been partially emptied.
Shaun, Holt, Avrille, Holt, Mark, Weatherall, Matthew, Masoli, Richard, Beasley   +4 more
openaire   +2 more sources

The rejuvenated pressurised metered dose inhaler

Expert Opinion on Drug Delivery, 2007
The pressurised metered-dose inhaler (pMDI) has now been available for 50 years. Once regarded as an inefficient and difficult-to-use device, the technology has evolved significantly over the last few years, particularly since the introduction of novel formulations containing hydrofluoroalkane (HFA) propellants.
John, Bell, Steve, Newman
openaire   +2 more sources

The Evolution of Pressurized Metered-Dose Inhalers from Early to Modern Devices

Journal of Aerosol Medicine and Pulmonary Drug Delivery, 2016
Contains fulltext : 171663.pdf (Publisher’s version ) (Closed access)Pressurized metered-dose inhalers (pMDIs) are sometimes viewed as old-fashioned and as having been superseded by dry powder inhalers (DPIs).
Nicolas Roche, P N Richard Dekhuijzen
exaly   +2 more sources

Floating Patterns of Metered Dose Inhalers

Journal of Asthma, 1997
As long as metered dose inhalers have existed, patients have sought a reliable method to determine if a given canister was still potent. Concerning beta agonists, the answer to this question may be lifesaving. Issues of compliance have made dating canisters or counting doses impractical.
B L, Wolf, K R, Cochran
openaire   +2 more sources

Nonprescription Epinephrine Metered-Dose Inhaler: To Be or Not To Be

Pediatric Allergy, Immunology, and Pulmonology, 2014
A new product, Epinephrine HFA, is being considered by the Food and Drug Administration (FDA) for marketing approval as a nonprescription bronchodilator inhaler for the treatment of the “temporary relief of mild symptoms of intermittent asthma in adults and children 12 years of age and older.” This product would serve as a ...
Kathryn, Blake, Hengameh, Raissy
openaire   +2 more sources

The Continued Need for Metered Dose Inhalers

Journal of Aerosol Medicine, 1995
The metered dose inhaler (MDI) is currently the most widely used device in the treatment of adult asthma. It is the delivery system of choice in general practice throughout the world where both MDIs and powder inhalers are available. Up to 70% of all UK adult asthma prescriptions are for an MDI and worldwide the figures are likely to be higher. The MDI
openaire   +2 more sources

Spacer Devices for Metered Dose Inhalers

Clinical Pharmacokinetics, 2004
Spacer devices are attachments to the mouthpieces of pressurised metered dose inhalers (pMDIs), and range from tube spacers with a volume of
openaire   +2 more sources

Principles of Metered-Dose Inhaler Design

Respiratory Care, 2005
The pressurized metered-dose inhaler (pMDI) was introduced to deliver asthma medications in a convenient and reliable multi-dose presentation. The key components of the pMDI device (propellants, formulation, metering valve, and actuator) all play roles in the formation of the spray, and in determining drug delivery to the lungs.
openaire   +2 more sources

Metered-Dose Inhalers, Dry Powder Inhalers, and Transitions

Respiratory Care, 2000
Since 1956, the pMDI has become the most commonly prescribed and used aerosol device in the world. While concerns about global warming have led to a worldwide ban of CFCs, new HFA-propelled pMDIs are in development, requiring an evolutionary transition in the technology.
openaire   +2 more sources

Pressurized Metered-Dose Inhalers

2019
Pressurized Metered-dose Inhalers (pMDIs) are complex drug-device combination products that are widely used to treat lung diseases, and may also be advantageously employed to deliver active pharmaceutical ingredients (APIs) to the systemic circulation through the lungs. pMDIs occupy ca.
Sandro R.P. da Rocha, Balaji Bharatwaj, Rodrigo S. Heyder, Lin Yang   +3 more
openaire   +1 more source