Results 191 to 200 of about 297,887 (387)
Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain [PDF]
, 2000 Mark R. Owen +2 more
openalex +2 more sources
Folate administration reduces circulating homocysteine levels in NIDDM patients on long‐term metformin treatment [PDF]
, 1998 Aasne K. Aarsand, Carlsen
openalex +1 more source
Pediatric Obesity: Influence on Drug Dosing and Therapeutics [PDF]
, 2018 Obesity is an ongoing global health concern and has only recently been recognized as a chronic disease of energy homeostasis and fuel partitioning. Obesity afflicts 17% of US children and adolescents.
Ameer, Barbara, PharmD, MBA, BCPS, FCP +1 more
core +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 968-979, April 2025.Abstract Sodium‐glucose co‐transporters (SGLTs) mediate sodium and glucose transport across cell membranes. SGLT2 inhibitors have a recognized place within heart failure (HF) guidelines. We evaluated the effect of sotagliflozin on HF and cardiovascular outcomes in participants with type 2 diabetes. Scopus, Medline, Embase and Central were searched from
Maria Anna Bantounou +7 more
wiley +1 more source
Journal of Functional Foods, 2019 Modulation of metformin transporters could affect its pharmacokinetics/pharmacodynamics. The effects of naringenin on the renal tubular Organic Cation Transporter 1 (OCT1) and 2 (OCT2) protein expressions and subsequently the metformin clearance in ...
Edith Pascale Mofo Mato +2 more
doaj
Effects of metformin on tyrosine kinase activity, glucose transport, and intracellular calcium in rat vascular smooth muscle [PDF]
, 1996 Ligia J. Domínguez
openalex +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi +6 more
wiley +1 more source
High dietary salt enhances acute depressor responses to metformin [PDF]
, 1999 Martin S. Muntzel
openalex +1 more source
ESC Heart Failure, EarlyView.The diagnostic pathway of high‐risk primary care patients through NT‐proBNP. Abstract Introduction Early detection of heart failure (HF), particularly in asymptomatic individuals, is essential for timely intervention. This study aimed to determine the prevalence of HF among high‐risk individuals in primary care using N‐terminal probrain natriuretic ...
Ahmet Celik +17 more
wiley +1 more source
R-211. Excessive withdrawal bleeding after the insulin sensitising drug ‘metformin’ in a patient with chronic hypo- or anovulatory cycles [PDF]
, 1999 J.G. Dolfing +4 more
openalex +1 more source