Results 171 to 180 of about 118,212 (266)

Do We Have Enough Evidence That Metformin Is Superior to Other Antidiabetic Drugs in Pancreatic Cancer Risk Reduction? [PDF]

Int J Mol Sci
Szymczak-Pajor I, Drzewoski J, Wenclewska S, Rogalska A, Śliwińska A.   +4 more
europepmc   +1 more source

Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases

Cell Proliferation, EarlyView.
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du, Joshua S. Fleishman, Shuang Wu, Yuan Zhou, Clara X. Wang, Haitong Wang, Yumin Wang, Hongquan Wang   +7 more
wiley   +1 more source

Combined Effect of Metformin and miR-145/miR-23b Co-Transfection on Proliferation and Progression in 2D and 3D Epithelial Ovarian Cancer Models. [PDF]

Cells
Rubio MA, Velásquez E, Antonucci S, Sánchez MJ, Romero C.   +4 more
europepmc   +1 more source

Maternal glycaemia and child educational attainment at age 5 in the Born in Bradford cohort

Diabetic Medicine, EarlyView.
Abstract Aims There is emerging evidence that maternal hyperglycaemia may be associated with adverse offspring neuro‐behavioural outcomes, which are foundational to educational success. We hypothesised that higher levels of maternal glucose would be associated with poorer educational attainment in early childhood.
Claire A. Wilson, Gillian Santorelli, Emily Simonoff, Louise M. Howard, Khalida Ismail, Rebecca M. Reynolds   +5 more
wiley   +1 more source

Antimicrobial and Synergistic Activity of Metformin Against <i>Helicobacter pylori</i>. [PDF]

Can J Infect Dis Med Microbiol
Rajab WH, Jaradat N, Abdo Q, Aljouda N, Qadi M.   +4 more
europepmc   +1 more source

Interventions for binge eating disorder in adults with type 2 diabetes: A systematic review

Diabetic Medicine, EarlyView.
Abstract Aims Binge eating disorder frequently co‐occurs with type 2 diabetes, creating a dual burden that may complicate both psychological well‐being and glycaemic management. Evidence on the effectiveness of health interventions in this population is limited.
Pernille Fiil Nybo, Nikolaj Vang Nielsen, Julie Drotner Mouritsen, Michael Einar Røder, Jakob Linnet   +4 more
wiley   +1 more source

Formulation of Metformin-Loaded Chitosan Nanoparticles and In Vivo Evaluation of Its Hypoglycemic Effects. [PDF]

Molecules
Awchee ZO, Ovenseri AC, Malkawi AS, Pozharani LB.   +3 more
europepmc   +1 more source

Evaluation of a secondary care multidisciplinary clinic for adults with early‐onset type 2 diabetes at high risk in Leicester, Leicestershire and Rutland

Diabetic Medicine, EarlyView.
Abstract Background Clinical services for adults with early‐onset type 2 diabetes (EOT2D) are in urgent need of improvement. Methods We evaluated a multi‐disciplinary clinic for individuals with EOT2D at high risk (HbA1c >9%/triglyceride >20 mmol/L), providing 2–3 flexibly arranged consultations per individual between March 2024 and September 2025 ...
Jonathan Goldney, Malak Hamza, Priscilla Sarkar, Harriet Morgan, Nicole Green, James Ridgeway, Victoria Alabraba, Laura Willcocks, Krupali Chandracant, Kashmala Javed, Rhys O'Callaghan, Finley Turner, Samuel Seidu, Claire L. Meek, Melanie J. Davies   +14 more
wiley   +1 more source

Metformin improves endotoxemia and alters folliculogenesis in women with polycystic ovary syndrome. [PDF]

Endocr Connect
Trzcinski M, Chudzicka-Strugala I, Kim K, Piekarski P, Spaczynski R, Zwoździak B, Banaszewska B, Pawelczyk L, Chang RJ, Duleba AJ.   +9 more
europepmc   +1 more source

Piloting an immersive virtual reality 3D self‐management education experience for adults with type 1 and type 2 diabetes mellitus: A qualitative study

Diabetic Medicine, EarlyView.
Abstract Aims Diabetes is a condition of global concern that can be mitigated through self‐management education. Virtual reality (VR) technology offers an immersive and interactive approach. It may promote self‐care and access to healthcare information.
Marion A. Waite, Olga Kozlowska, Clare Martin, Michal Krezalek, David Duce, Arantza Aldea, Mark Green   +6 more
wiley   +1 more source