Results 151 to 160 of about 223,349 (294)

Safety and Efficacy of Glucagon‐Like Peptide‐1 Receptor Agonists Use in Elderly People With Obesity—A Meta‐Analysis

Obesity, EarlyView.
ABSTRACT Objective This meta‐analysis evaluates the safety and efficacy of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) for the treatment of older adults with obesity compared to younger individuals. Methods A systematic review was conducted following PRISMA guidelines (PROSPERO CRD420251074381).
Inês Rego de Figueiredo, Filipa Sofia Simas, Angela Ghiletchi, João Oliveira Torres, José Silva‐Nunes   +4 more
wiley   +1 more source

Metformin and epigenetic age in non-diabetic older people with HIV in Madrid (METFORAGING): a double-blind, randomised, placebo-controlled, pilot trial. [PDF]

EClinicalMedicine
Marcelo-Calvo C, Esteban-Cantos A, Jurado F, Montejano R, Rodríguez-Centeno J, Gutiérrez-García L, de Gea-Grela A, Martínez-Martín P, Vidal AD, de Miguel R, Oñoro-López CM, González JC, Martín-Carbonero L, Bernardino JI, Colino RM, Pérez de Villar NG, Rodés B, Arribas JR.   +17 more
europepmc   +1 more source

Twenty‐Four Month Outcomes From a Real‐World Telehealth Obesity Treatment Clinic Using Obesity Medications

Obesity, EarlyView.
ABSTRACT Objective Antiobesity medications (AOMs) are indicated for long‐term use; however, evidence of their real‐world long‐term efficacy is limited. This study describes clinical outcomes from 18‐ and 24‐month use of AOMs in a telemedicine weight management clinic.
Kathleen R. Ruddiman, Young‐Rock Hong, Jamy Ard, Rebecca Jones, Adam Medcalf, Gary D. Foster, Jamil Alkhaddo, Michelle Cardel   +7 more
wiley   +1 more source

Effect of metformin on pancreatic neuroendocrine tumors of multiple endocrine neoplasia type 1. [PDF]

J Neuroendocrinol
Kozlov SV, Agarwal SK, Guerin TM, Lawrence WC, Bassel LL, Graf A, Jha S, Weinstein LS, Blau JE, Del Rivero J.   +9 more
europepmc   +1 more source

Parental Communication With Children Around Obesity Management Medications, Weight Loss, and Health Behavior Change

Obesity, EarlyView.
ABSTRACT Objective This study aimed to describe parental communication with children around obesity management medications (OMMs) and child, parent, and family factors associated with communication. Methods Parents (N = 211; 80% mothers; 89% White) prescribed OMMs at a medical center participated in a survey about communication with children about OMM ...
Keeley J. Pratt, Selena Gonzlez‐Jordan, Sabrena F. Noria, Joseph A. Skelton   +3 more
wiley   +1 more source

Metformin drives HIF-1α-mediated dual metabolic reprogramming to enhance γδ T cell therapy in triple-negative breast cancer. [PDF]

Cancer Immunol Immunother
Qin X, Zhong H, Liu M, Yu T, Ma R, Zhou Y, Chen J, Liu F, Wang X, Long J.   +9 more
europepmc   +1 more source

Medication prescription patterns in cancer rehabilitation physiatry outpatients: A multicenter retrospective study

PM&R, EarlyView.
Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen, Nafis Eghrari, David Leong, Philip Chang, Jasmine Zheng, Amy Ng, Richard Wilson, Mary Vargo   +7 more
wiley   +1 more source

Factors potentiating risk of higher lactate level associated with metformin therapy: a cross-sectional study in an ambulatory care setting. [PDF]

Ther Adv Endocrinol Metab
Alqurain A, Alrossies AS, Almuayli AA, Alherz AM, Alkhamees MS, Al-Ghafli H, Alsaffar N, Zawiah M.   +7 more
europepmc   +1 more source

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang, Vaishnavi Veerareddy, Xiaojiao Tang, Kevin J. Thompson, Sunil Krishnan, Krishna R. Kalari, Karunya K. Kandimalla   +6 more
wiley   +1 more source

Metformin Toxicity Unmasked by Obstructive Uropathy: A Case of Metformin Associated Lactic Acidosis and Euglycemic Diabetic Ketoacidosis. [PDF]

Discoveries (Craiova)
Khan RS, Patla A, Ayyazuddin M, Michaeil G, Shah R, Rajaram S.   +5 more
europepmc   +1 more source