Results 141 to 150 of about 167,880 (309)
Saxagliptin and Metformin in Fixed Combination for the Treatment of Type 2 Diabetes in Adults
, 2013 Type 2 diabetes affects millions of people worldwide and significantly contributes to morbidity and mortality of those affected by it. Current guidelines recommend individualized treatment regimens following first line metformin therapy.
Mary S. Klein +2 more
core +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 968-979, April 2025.Abstract Sodium‐glucose co‐transporters (SGLTs) mediate sodium and glucose transport across cell membranes. SGLT2 inhibitors have a recognized place within heart failure (HF) guidelines. We evaluated the effect of sotagliflozin on HF and cardiovascular outcomes in participants with type 2 diabetes. Scopus, Medline, Embase and Central were searched from
Maria Anna Bantounou +7 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi +6 more
wiley +1 more source
, 2018 Mingyue Rao,1–3 Chenlin Gao,1,2 Man Guo,2 Betty Yuen Kwan Law,1,4 Yong Xu1,2 1Faculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macau, China; 2Department of Endocrinology, 3Department of Oncology ...
Guo M, Law BYK, Rao M, Gao C, Xu Y
core
Kaplan-Meier survival curves for the metformin group (dashed line) and non-metformin group.
, 2016 Kaplan-Meier survival curves for the metformin group (dashed line) and non-metformin group.
Chenwi M. Ambe (3180897) +4 more
core +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background Treatment with the sodium‐glucose co‐transporter 2 (SGLT2) inhibitor canagliflozin in insulin dysregulated (ID) horses has shown promising results in randomised clinical trials. Larger field studies are needed to further evaluate treatment responses and potential adverse effects under real‐world conditions.
Moa Hällbom +3 more
wiley +1 more source
The use of metformin is associated with decreased lumbar radiculopathy pain
, 2013 Amber Taylor,1 Anton H Westveld,2,6 Magdalena Szkudlinska,1 Prathima Guruguri,1 Emil Annabi,3 Amol Patwardhan,3 Theodore J Price,4 Hussein N Yassine51Department of Medicine, University of Arizona, Tucson, AZ, USA; 2Statistics Laboratory, Bio5 Institute ...
Westveld AH +7 more
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Equine Veterinary Journal, EarlyView.Abstract Background Lamellar endoplasmic reticulum (ER) stress occurs in hyperinsulinemia‐associated and sepsis‐related laminitis. Adiponectin is associated with reduced laminitis risk and inhibits ER stress in other species. Objectives To induce ER stress in ex vivo equine lamellar cells using pharmacological agents.
Marine A. Barnabé +6 more
wiley +1 more source
Exploration, EarlyView.Chronic stressors trigger systemic immune remodeling marked by myeloid expansion and lymphoid suppression, and this immune imbalance subsequently drives tissue pathology through proinflammatory signaling and senescence amplification, with the lung and kidney confirmed as the most vulnerable target organs.
Mengnan Li +23 more
wiley +1 more source