Results 161 to 170 of about 148,910 (315)

Weight-Lowering Drugs and Natural Female Fertility-A Systematic Review and Meta-Analysis. [PDF]

Clin Obes
Alnaimi SJ, Alsugeir DM, Wei L, Harvey K, Brauer R.   +4 more
europepmc   +1 more source

Small‐Molecule Kinase Inhibitors Modulating Circadian Rhythms

Medicinal Research Reviews, EarlyView.
ABSTRACT The circadian clock mechanism generates 24‐h rhythms crucial for regulating various physiological processes, and its dysregulation has been implicated in numerous diseases. In cells, the circadian clock operates through a transcriptional‐translational feedback loop, where phosphorylation plays a pivotal role in maintaining accurate circadian ...
Irene Castellino, Manuela Bartolini, Rudolf Andrys, Kamil Musilek   +3 more
wiley   +1 more source

Efficacy of Metformin in Prevention of Glucocorticoid-Induced Hyperglycemia in Patients Without Diabetes: A Meta-Analysis. [PDF]

Endocrinol Diabetes Metab
Murtaza S, Murtaza F, Yasin MU, Shahid A, Shahid M, Rehan MMB, Ata F, Asghar MS, Eljack MMF.   +8 more
europepmc   +1 more source

Metformin increases pressure pain threshold in lean women with polycystic ovary syndrome

, 2016
Marta Kiałka,1 Tomasz Milewicz,1 Krystyna Sztefko,2 Iwona Rogatko,2 Renata Majewska3 1Department of Gynecological Endocrinology, Jagiellonian University, Medical College, Kraków, Poland; 2Department of Clinical Biochemistry, Jagiellonian ...
Rogatko I, Milewicz T, Sztefko K, Kiałka M, Majewska R   +4 more
core  

Ferroptosis and Its Emerging Role in Gestational Diabetes Mellitus

Medicine Advances, EarlyView.
Ferroptosis contributes to the development of gestational diabetes mellitus (GDM) through iron overload, lipid peroxidation, and antioxidant system disruption. These changes impair adipocyte and β‐cell function, promoting insulin resistance and hyperglycemia.
Jinfeng Xu, Yuan Tian, Hongbin Zhu, Bing Peng, Chunheng Mo   +4 more
wiley   +1 more source

Metformin dual-targets metabolism and survival pathways in BPDCN. [PDF]

iScience
Mekkaoui Z, Dal Zuffo L, Vetter M, Fredon M, Poussard M, Biichle S, Mougey V, Mercier-Letondal P, Rolin G, Godet Y, Perruche S, Garnache-Ottou F, Saas P, Aribi M.   +13 more
europepmc   +1 more source

Association of Glucagon‐Like Peptide‐1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes

Obesity, EarlyView.
ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu, Hao Dai, Huilin Tang, William T. Donahoo, Thomas J. George, Ramon C. Sun, Sizun Jiang, Aik Choon Tan, Yi Guo, Jonathan D. Licht, John M. Allen, Kelvin P. Lee, Jingchuan Guo, Jiang Bian   +13 more
wiley   +1 more source

Metformin and Gastric Carcinogenesis: Stage-Specific Effects? [PDF]

Korean J Helicobacter Up Gastrointest Res
Kim YJ.
europepmc   +1 more source

Adherence, satisfaction, and experience with metformin 500 mg prolonged release formulation in Indian patients with type 2 diabetes mellitus: a postmarketing observational study

, 2019
KM Prasanna Kumar,1 Manoj Chawla,2 Ami Sanghvi,3 Nadiminty G Sastry,4 Chaitanya Kotla,5 Sanjeev Phatak,6 Sanjay Choudhari7 1Centre for Diabetes and Endocrine Care, Bangalore, Karnataka, India; 2Lina Diabetes Care and Mumbai Diabetes Research Centre ...
Chawla M, Phatak S, Choudhari S, Sanghvi A, Kotla C, Kumar KMP, Sastry NG   +6 more
core  

Safety and Efficacy of Glucagon‐Like Peptide‐1 Receptor Agonists Use in Elderly People With Obesity—A Meta‐Analysis

Obesity, EarlyView.
ABSTRACT Objective This meta‐analysis evaluates the safety and efficacy of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) for the treatment of older adults with obesity compared to younger individuals. Methods A systematic review was conducted following PRISMA guidelines (PROSPERO CRD420251074381).
Inês Rego de Figueiredo, Filipa Sofia Simas, Angela Ghiletchi, João Oliveira Torres, José Silva‐Nunes   +4 more
wiley   +1 more source