Results 191 to 200 of about 148,910 (315)

Metformin and Flutamide Combination Therapy's Efficacy and Safety in Prostate Cancer Cell Lines. [PDF]

Prostate Cancer
Rezaeian A, Khatami F, Hosseini SR, Oskouie IM, Mirzaei A, Mashhadi R, Ghajar HA, Khoshchehreh M, Tavoosian A, Kazem Aghamir SM.   +9 more
europepmc   +1 more source

Pre‐Pregnancy Body Mass Index, Diabetes Status, and Gestational Age‐Specific Stillbirth Risk: A Nationwide Retrospective Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To quantify and compare the gestational age (GA)‐specific risks of stillbirth across pre‐pregnancy body mass index (BMI) categories, stratified by pre‐pregnancy diabetes status: Design Retrospective population‐based cohort study. Setting United States from 2022 to 2023.
Jeffrey N. Bone, K. S. Joseph, Laura Magee, Chantal Mayer, Sarka Lisonkova   +4 more
wiley   +1 more source

Molecular Insights into the Interaction Between Metformin and Caffeine: The Time-Dependent Antagonism and Modulation of p53 Signaling in Cancer Cells. [PDF]

Molecules
Zeljković V, Bogavac M, Dekić M, Minić S, Mahmutović E, Kunkin V, Marković Z, Karaman M.   +7 more
europepmc   +1 more source

Microbial and Metabolic Correlates of Endometrial Dysfunction in Polycystic Ovary Syndrome: A Translational Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Women with polycystic ovary syndrome (PCOS) exhibit a substantially increased risk of miscarriage, yet the underlying mechanisms remain inadequately understood. This study aimed to investigate whether specific gut microbial dysbiosis and metabolic disturbance are associated with and may potentially contribute to endometrial ...
Mengyu Jing, Xi Chen, Meiyan Jiang, Huiya Fang, Xiaoming Zhu, Xuejing Jin, Yonghui Jiao, Ningning Hou, Weiwei Gong, Aixia Liu   +9 more
wiley   +1 more source

A systematic review and meta-analysis of the relative benefit of dual versus single oral hypoglycaemic therapy following diagnosis with type 2 diabetes (T2D). [PDF]

Diabet Med
Kelly M, Saluja S, Ellis HL, Jamil S, Whyte MB, Heald A.   +5 more
europepmc   +1 more source

Clinical Intervention Following Detection of Incident Diabetes Within a Large Psychiatric Service System: A Chart Review Study

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Individuals with mental illness have a markedly reduced life expectancy, partly due to a significantly increased risk of developing type 2 diabetes, driven by lifestyle factors and the adverse metabolic effects of psychotropic medications.
Pernille Kølbæk, Christopher Rohde, Maria Speed, Henrik Holm Thomsen, Søren Dinesen Østergaard   +4 more
wiley   +1 more source

Metformin Alleviates Stress-Induced Premature Senescence of Vascular Endothelial Cells by Regulating Mitocytosis. [PDF]

Int J Mol Sci
Lu H, Mu Q, Wang B, Chen Y, Zeng B, Gu L, Zhao W.   +6 more
europepmc   +1 more source

Use of Glucagon‐Like Peptide 1 Receptor Agonists and the Associated Risk of Hospitalisation in Bipolar Disorder, From a Nationwide Cohort, 2009–2024

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Diabetes, obesity and bipolar disorder often co‐occur and may have shared pathophysiology. Glucagon‐like peptide 1 receptor agonists (GLP‐1RA) treat diabetes and obesity but their impact on bipolar disorder is unknown. In this era of stagnated pharmacotherapy, we examined psychiatric hospitalisation and absence from work due to ...
Heidi Taipale, Mark Taylor, Markku Lähteenvuo, Ellenor Mittendorfer‐Rutz, Antti Tanskanen, Jari Tiihonen   +5 more
wiley   +1 more source

Impact of Metformin and Diabetes on Tumor Response to Total Neoadjuvant Therapy in Advanced Rectal Cancer: A Multicenter Retrospective Cohort Study

Asia-Pacific Journal of Clinical Oncology, EarlyView.
In advanced rectal cancer patients receiving total neoadjuvant therapy (TNT), overall tumor response did not differ by diabetes status or metformin use. However, among diabetic patients, metformin use was associated with higher overall complete response rates. These findings suggest a potential benefit of metformin in enhancing TNT response in diabetic
Sergei Bedrikovetski, Mahima Raju, Tracy Fitzsimmons, Ishraq Murshed, Timothy J. Price, Michael Penniment, Sudarsha Selva‐Nayagam, Tarik Sammour   +7 more
wiley   +1 more source

Innovative Biosensor Platforms for the Detection of Metformin in Diabetes Management. [PDF]

Int J Anal Chem
Jafarzadeh S, Shaterian E, Jafarisis S, Mohammadi M, Azizian H, Shiri S, Mobed A.   +6 more
europepmc   +1 more source