Results 201 to 210 of about 205,038 (298)

Linkage disequilibrium score regression identifies genetic correlations between hepatocellular carcinoma and clinically relevant traits

International Journal of Cancer, EarlyView.
What's New? Hepatocellular carcinoma arises from a combination of environmental and genetic factors, with the latter playing a potentially more significant role in nonviral hepatocellular carcinoma. Here, the authors characterized the genetic correlations and heritability between nonviral hepatocellular carcinoma and 901 epidemiologic, behavioral, and ...
Younghun Han, Vikram R. Shaw, Jinyoung Byun, Aaron P. Thrift, Catherine Zhu, Donghui Li, Rikita I. Hatia, Robin Kate Kelley, Sean P. Cleary, Anna S. Lok, Paige M. Bracci, Jennifer B. Permuth, Roxana Bucur, Jennifer Knox, Jian‐Min Yuan, Amit G. Singal, Prasun K. Jalal, R. Mark Ghobrial, Yuko Kono, Dimpy P. Shah, Mindie H. Nguyen, Neehar D. Parikh, Richard Kim, Hui‐Chen Wu, Hashem El‐Serag, Ping Chang, Yun Shin Chun, Jian Gu, Chad Huff, Asif Rashid, Lu‐Yu Hwang, Alison P. Klein, Saira A. Khaderi, Ahmed O. Kaseb, Kathrine A. McGlynn, Lewis R. Roberts, Manal M. Hassan, Christopher I. Amos   +37 more
wiley   +1 more source

Effects of Metformin on Cancer Survival Among Men Diagnosed with Advanced Prostate Cancer Treated with Androgen-Deprivation Therapy: Emulating a Target Trial. [PDF]

Cancers (Basel)
Lopez DS, Polychronopoulou E, Abdelgadir O, Greenberg R, Cowell LG, Messiah SE, Kuo YF.   +6 more
europepmc   +1 more source

Confirmation of Metformin-Induced Acute Generalized Exanthematous Pustulosis Through a Positive Dechallenge-Rechallenge Test: A Case Report and Review of Cutaneous Manifestations Associated With Metformin [PDF]

Haifa A Alfalah, Khalid Nabil Nagshabandi   +1 more
openalex   +1 more source

Maternal diabetes mellitus during pregnancy as a risk factor for strabismus and refractive errors in the offspring—A large‐scale national study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To investigate whether maternal diabetes during pregnancy is associated with increased risk of strabismus and refractive errors (RE) in their offspring. Methods This retrospective cohort study utilized electronic medical records from Clalit Health Services (CHS) in Israel, 2001–2023. Births were categorized by maternal diabetes type (
Nir Amitai, Tomer Kerman, Tamar Eshkoli, Ahed Imtirat, Amichai Raz, Itamar Ben Shitrit, Dor Marciano, Eyal Sheiner, Erez Tsumi   +8 more
wiley   +1 more source

The metformin mediated MAPK signaling pathway influences D-Xylose regulation during diabetic kidney disease therapy. [PDF]

Commun Med (Lond)
Xie D, Zhu Y, Guo S, Li H, Wang Z, Wang X, Cai Y, Chai J, Wang Y, Hu Z, Wang S, Chen L, Qiu S, Xie Y, Zhang A.   +14 more
europepmc   +1 more source

Metformin Promotes T-Cell Recruitment in a Novel 3D Model of Omental Metastasis

, 2023
Silver Homa, Esmeralda Delgado, Peter C. Hart   +2 more
openalex   +1 more source

The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin

Science, 2005
R. Shaw, Katja A. Lamia, Debbie S. Vasquez, Seung-Hoi Koo, N. Bardeesy, R. DePinho, M. Montminy, L. Cantley   +7 more
semanticscholar   +1 more source

Artificial Intelligence Revolutionizes Anti‐Infective Drug Discovery: From Target Identification to Lead Optimization

iMetaMed, EarlyView.
Artificial intelligence (AI) technology is revolutionizing antimicrobial drug development. In response to increasingly severe antimicrobial resistance challenges, AI can efficiently predict pathogen evolutionary trends, identify potential drug targets, and accelerate compound design and optimization, thereby significantly shortening the development ...
Kexin Li, Quan Yuan, Chang Qi, Ying Shi, Hong Yang, Anqi Lin, Shuofeng Yuan   +6 more
wiley   +1 more source

Mendelian Randomization and Bioinformatics Analysis Reveal the Potential Protective Role of Metformin in Primary Liver Cancer. [PDF]

Food Sci Nutr
Ma Y, Qi J, Chen Z, Zhang Y, Liu K, Suo J, Chen B, Bu Y.   +7 more
europepmc   +1 more source

Efficacy of triple combination oral hypoglycaemic therapy using rosiglitazone, metformin and sulphonylurea in lowering HbA_1c [PDF]

, 2003
Jonathan Byrne, Satish K. Garg, Abhinav Vaidya, SM Rajbhandari, SC Wallis   +4 more
openalex   +1 more source