Results 241 to 250 of about 297,887 (387)

Pharmacokinetic Characterization of Iopamidol and Iohexol for Optimizing Measured Glomerular Filtration Rate Assessment in Clinical Practice and Drug Development

The Journal of Clinical Pharmacology, EarlyView.
Abstract Accurate kidney function assessment supports healthcare and clinical decision‐making in practice and drug development. Measured glomerular filtration rate (mGFR) via iohexol clearance is the gold standard, but cost, supply issues, and logistical challenges limit its clinical use.
Levi Hooper, Michael Heung, Lu Wang, Aleksas Matvekas, Radin Alikhani, Michael T. Kenes, Kathleen A. Stringer, Bruce A. Mueller, Manjunath P. Pai   +8 more
wiley   +1 more source

Metformin-Driven Activation of Polymorphic Follicle-Stimulating Hormone Receptors for Polycystic Ovary Syndrome Treatment: A Computational Study. [PDF]

Med Sci Monit
Alzahrani KJ.
europepmc   +1 more source

Metformin and the united kingdom prospective diabetes study: a commentary [PDF]

, 2000
Ian W Campbell
openalex   +1 more source

Clinical Evaluation of Drug–Drug Interactions Between Bictegravir and Strong Inhibitors/Inducers of the CYP3A4, UGT1A1, or P‐gp Pathways

The Journal of Clinical Pharmacology, EarlyView.
Abstract In addition to antiretroviral therapy (ART), people with HIV often take medications to treat comorbidities. It is therefore important to assess these medications for potential drug‐drug interactions, which may affect the safety and efficacy of ART. Three phase I studies were conducted in adult participants without HIV. The pharmacokinetics (PK)
Priyanka Arora, Hui Liu, John Ling, Jason T. Hindman, Dhananjay D. Marathe   +4 more
wiley   +1 more source

Pleiotropic Effects of Metformin on the Chemotherapy Response of HPV-Positive Cancer Cells. [PDF]

J Med Virol
Avenhaus A, Kuhn BJ, Velimirović M, Strobel TD, Bulkescher J, Lohrey C, Krijgsveld J, Hoppe-Seyler F, Hoppe-Seyler K.   +8 more
europepmc   +1 more source

Metformin-Medikation [PDF]

Der Urologe, 2014
openaire   +1 more source

Mortality and cardiovascular disease after cholecystectomy in type 2 diabetes: A nationwide longitudinal cohort study

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
Abstract Background The long‐term effects of cholecystectomy on mortality and cardiovascular disease (CVD) in patients with diabetes have not been evaluated. In the present study, we investigated the longitudinal effects of cholecystectomy on mortality and CVD in a population‐based cohort with type 2 diabetes (T2D). Methods In total, 2 216 930 national
Han Na Jung, Ji Hye Heo, Eun Roh, Kyung‐Do Han, Jun Goo Kang, Seong Jin Lee, Sung‐Hee Ihm   +6 more
wiley   +1 more source

Metformin and reduced risk of cancer in diabetic patients

British medical journal, 2005
J. Evans, L. Donnelly, A. Emslie-Smith, D. Alessi, A. Morris   +4 more
semanticscholar   +1 more source

Metformin reverses periodontal destruction caused by experimental periodontitis by inhibiting interleukin‐1β activity

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis is a destructive disease that affects periodontal tissue. While current research focuses on disease management, research on tissue repair remains limited. Metformin, a first‐line medication for diabetes treatment, has positive effects on bone health in nondiabetic patients.
Zhao Wang, Ju Han Song, Jung‐Woo Kim, Seung‐Hee Kwon, Xianyu Piao, Sin‐Hye Oh, Suk‐Gyun Park, Sun‐Hun Kim, Je‐Hwang Ryu, Ok‐Su Kim, Jeong‐Tae Koh   +10 more
wiley   +1 more source

Metformin modulates oxidative stress via activation of AMPK/NF-κB signaling in Trisomy 21 fibroblasts: an <i>in vitro</i> study. [PDF]

Front Mol Biosci
Buczyńska A, Malinowski P, Żbikowski A, Krętowski AJ, Zbucka-Krętowska M.   +4 more
europepmc   +1 more source