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Drugs, 2005
The thiazolidinedione rosiglitazone and the biguanide metformin are effective antihyperglycaemic agents with different modes of action; rosiglitazone primarily increases insulin sensitivity, whereas metformin primarily reduces hepatic glucose output. Antihyperglycaemic combination therapy is often required to achieve effective glycaemic control.
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The thiazolidinedione rosiglitazone and the biguanide metformin are effective antihyperglycaemic agents with different modes of action; rosiglitazone primarily increases insulin sensitivity, whereas metformin primarily reduces hepatic glucose output. Antihyperglycaemic combination therapy is often required to achieve effective glycaemic control.
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Tijdschrift voor praktijkondersteuning, 2014
Na de ontdekking en internationale introductie in 1923 van insuline voor de behandeling van diabetes mellitus, is in 1959 metformine internationaal in de handel gebracht als een van de eerste orale bloedglucoseverlagende middelen.
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Na de ontdekking en internationale introductie in 1923 van insuline voor de behandeling van diabetes mellitus, is in 1959 metformine internationaal in de handel gebracht als een van de eerste orale bloedglucoseverlagende middelen.
openaire +1 more source
Diabetes Technology & Therapeutics, 2016
Ranjit, Unnikrishnan, Viswanathan, Mohan
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Ranjit, Unnikrishnan, Viswanathan, Mohan
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