Results 251 to 260 of about 167,880 (309)

Metformin Exposure in Pregnancy and Childhood Developmental Outcomes.

open access: yesJAMA Netw Open
Gordon H   +10 more
europepmc   +1 more source

METFORMIN

Endocrinology and Metabolism Clinics of North America, 1997
Metformin, a dimethylbiguanide, was first synthesized in 1929 and was shown to be a potent hypoglycemic agent. It was rediscovered in 1957 and was widely used in Europe to treat obese type II patients. Metformin resurfaced in the 1980s and was shown to increase insulin sensitivity; this has led to its introduction to clinical practice in the United ...
P M, Bell, D R, Hadden
openaire   +2 more sources

The Metformin Paradox

Current Diabetes Reviews, 2020
Introduction: The Diabetes Prevention Program study results indicated that metformin therapy was not as beneficial as a lifestyle modification for delaying the development of type 2 diabetes in individuals at high risk of the disease. A key feature in the etiology of type 2 diabetes mellitus, which appears in the prediabetic phase, is a significant ...
Rob N M, Weijers, Dick J, Bekedam
openaire   +2 more sources

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