Results 291 to 300 of about 297,887 (387)

The use of metformin (Siofora®) in patients with abdominal type of obesity

, 2000
И. И. Дедов, С А Бутрова, Б. П. Мищенко, Ф Х Дзгоева   +3 more
openalex   +1 more source

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang, Vaishnavi Veerareddy, Xiaojiao Tang, Kevin J. Thompson, Sunil Krishnan, Krishna R. Kalari, Karunya K. Kandimalla   +6 more
wiley   +1 more source

Paternal Preconception Metformin Use and Offspring Risk of Congenital Malformations.

JAMA Netw Open
Huybrechts KF, Straub L, Rotem RS, Bateman BT, Hernández-Díaz S.   +4 more
europepmc   +1 more source

Association of metformin with risk of digestive tract cancers from a drug target mendelian randomization and cell experiments. [PDF]

Discov Oncol
Wang Y, Cao X, Ren J, Chen R, Zhang X, Liu C, Jia Y, Lin T.   +7 more
europepmc   +1 more source

Evaluation of Four Semi‐Mechanistic Models for Predicting Glycemic Control With a Glucagon Receptor Antagonist in People With Type 2 Diabetes

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Glycated hemoglobin (HbA1c) is the gold standard for measuring long‐term glycemic efficacy over at least 3 months in Type 2 diabetes (T2D). Being able to predict HbA1c using glucose response from studies of less than 3 months would be useful.
Austin Yue Feng Tan, Karen Schneck, Parag Garhyan, Eric Chun Yong Chan, Lai San Tham   +4 more
wiley   +1 more source

Role of Environmental Photocatalysts and Organic Matter on the Degradation and Toxicity of Metformin Hydrochloride. [PDF]

Toxics
Khan R, Regalado J, Kanaththage MI, Patidar PL, Rubasinghege G.   +4 more
europepmc   +1 more source

Recent Advances in Nanomedicine‐Mediated Abdominal Aortic Aneurysm Treatment

Small Methods, EarlyView.
Bridge the gap. Emerging strategies such as nanoparticle platforms and cell therapies may help advance the medication management of abdominal aortic aneurysm from laboratory to clinical application. By enhancing the precision, efficacy, ad comprehensiveness of drug delivery, a wide range of studies have obtained positive outcomes and are summarized in ...
Xinchen Lu, Quanyin Hu
wiley   +1 more source

Iron Deficiency Anemia and Oxidative Stress in Type 2 Diabetic Patients on Metformin: A Meta-Analysis. [PDF]

Cureus
Rubbani A, Khalid D, Nadeem S, Jamali AG, Rizvi SAB, Rabbani A, Sahitia S, Asfand Yar M, Albatrawi AAM, Abdul-Latif MM.   +9 more
europepmc   +1 more source

A comparative study between melt granulation/compression and hot melt extrusion/injection molding for the manufacturing of oral sustained release thermoplastic polyurethane matrices [PDF]

, 2016
Boone, Matthieu, De Beer, Thomas, Grymonpré, Wouter, Mertens, Pieter, Remon, Jean Paul, Van Bockstal, Pieter-Jan, Van Hoorebeke, Luc, Verstraete, Glenn, Vervaet, Chris   +8 more
core   +2 more sources

Alternate Day Fasting Enhances Intestinal Epithelial Function During Aging by Regulating Mitochondrial Metabolism

Aging Cell, EarlyView.
Alternate day fasting alleviates aging‐induced intestinal epithelial barrier damage by regulating mitochondrial metabolism in small intestinal stem cells. ABSTRACT With advancing age, the decline in intestinal stem cell (ISC) function can lead to a series of degenerative changes in the intestinal epithelium, a critical factor that increases the risk of
Heng Quan, Yao Lu, Yingying Lin, Peng Xue, Yuning Zhang, Yuqi Wang, Weiru Yu, Xiaoya Lin, Wuqi Yang, Cong Lv, Yafei Zhang, Fazheng Ren, Huiyuan Guo   +12 more
wiley   +1 more source