Results 311 to 320 of about 102,331 (342)
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BMJ, 2012
When I was young, I drank to get wrecked. In the hospitals in the 1980s and 1990s, I witnessed the complications of heroin addiction: amputations, gangrene, endocarditis, sepsis, hepatitis, and HIV. A stream of ambulances spilt half dead overdosers onto accident and emergency trolleys. There was no drug for opioid substitution—for example, methadone—so
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When I was young, I drank to get wrecked. In the hospitals in the 1980s and 1990s, I witnessed the complications of heroin addiction: amputations, gangrene, endocarditis, sepsis, hepatitis, and HIV. A stream of ambulances spilt half dead overdosers onto accident and emergency trolleys. There was no drug for opioid substitution—for example, methadone—so
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Methadone Maintenance: A Comparison of Methadone Treatment Subjects and Methadone Treatment Dropouts
International Journal of the Addictions, 1975Commonly agreed upon goals in conjunction with methadone maintenance have been (1) a return to legitimate employment, (2) cessation or substantial reduction in criminal behavior, (3) reduction in the amount of time spent in drug-seeking behavior, (4) involvement with a social system in which there is a positive reinforcement for relating to people, and
Williams Wv, Lee J
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Annals of Internal Medicine, 1973
Excerpt To the editor: The case of a patient recently seen by us is pertinent to the methadone-Tang® problem described in a letter that appeared in the May 1972 issue (p. 830).
A. Mitchell Smith +2 more
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Excerpt To the editor: The case of a patient recently seen by us is pertinent to the methadone-Tang® problem described in a letter that appeared in the May 1972 issue (p. 830).
A. Mitchell Smith +2 more
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Archives of General Psychiatry, 1973
Methadone hydrochloride produces subjective changes similar to those produced by heroin and is approximately equipotent to morphine when both are administered subcutaneously and one half as potent when administered orally. Chronically administered methadone produces sedation, lethargic apathy, reduction in sexual interest and activity, hemodilution ...
W. R. Martin +6 more
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Methadone hydrochloride produces subjective changes similar to those produced by heroin and is approximately equipotent to morphine when both are administered subcutaneously and one half as potent when administered orally. Chronically administered methadone produces sedation, lethargic apathy, reduction in sexual interest and activity, hemodilution ...
W. R. Martin +6 more
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Effects of buprenorphine and methadone in methadone-maintained subjects
Psychopharmacology, 1995Buprenorphine, a partial mu opioid agonist, is an experimental medication under development for the treatment of opioid dependence as an alternative to methadone maintenance. The present study examined the relationship between level of opioid physical dependence and response to buprenorphine administration as part of a program to develop procedures for
Harry L. June +5 more
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Methadone—Disulfiram Interaction During Methadone Maintenance
The Journal of Clinical Pharmacology, 1980In an attempt to characterize a possible drug interaction between methadone and disulfiram, 500 mg/day insulfiram was administered orally for seven days to seven subjects on methadone maintenance. Plasma methadone concentrations and urinary excretion of methadone and its pyrrolidine and pyrrolidone metabolites were measured and subjective symptoms of ...
Theodore G. Tong +2 more
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Annals of the New York Academy of Sciences, 1976
We have demonstrated the dangers of alcoholism that complicate methadone treatment of heroin addiction. In future papers, we will attempt to identify contributory factors and suggest interventionist techniques. In the final analysis, however, rehabilitation programs, vocational programs, and, above all, alleviation of the dreadful socioeconomic ...
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We have demonstrated the dangers of alcoholism that complicate methadone treatment of heroin addiction. In future papers, we will attempt to identify contributory factors and suggest interventionist techniques. In the final analysis, however, rehabilitation programs, vocational programs, and, above all, alleviation of the dreadful socioeconomic ...
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Plasma methadone monitoring with methadone maintenance treatment
Drug and Alcohol Dependence, 1994Substantial evidence exists to support the effectiveness of methadone maintenance treatment (MMT), particularly with regard to reductions in intravenous drug use (Schuster, 1991) and crime (Bell et al., 1992); and to its safety and cost effectiveness compared to other (drug-free) alternatives (Glass, 1993).
Kim Wolff, Alastair Hay
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Methadone, methadone treatment and non-fatal overdose
Drug and Alcohol Dependence, 2000This paper provides a mainly qualitative investigation of the role of methadone and methadone treatment in non-fatal illicit drug overdose. During 1997 and 1998, semi-structured interviews were conducted with 33 individuals in six hospital accident and emergency departments in two Scottish cities.
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