Results 21 to 30 of about 37,528 (250)

Methamphetamine-induced encephalopathy in the absence of hyperammonemia

open access: yesBMC Psychiatry, 2023
Background Methamphetamine is an addictive drug with various effects on the neurotransmitters in the central nervous system. Methamphetamine-induced encephalopathy in the absence of hyperammonemia presents a unique challenge in a clinical setting ...
Jessica M Rabbany   +4 more
doaj   +1 more source

Methamphetamine administration increases hepatic CYP1A2 but not CYP3A activity in female guinea pigs.

open access: yesPLoS ONE, 2020
Methamphetamine use has increased over the past decade and the first use of methamphetamine is most often when women are of reproductive age. Methamphetamine accumulates in the liver; however, little is known about the effect of methamphetamine use on ...
Jia Yin Soo   +6 more
doaj   +1 more source

Protective Effects of Isoliquiritigenin Against Methamphetamine-Induced Neurotoxicity in Mice

open access: yesJournal of Pharmacological Sciences, 2009
Isoliquiritigenin (ISL) suppresses cocaine-induced extracellular dopamine levels and has a neuroprotective effect in cocaine-treated rat brain. Here, we examine the effect of ISL on methamphetamine-induced striatal neurotoxicity.
Min Jung Lee   +3 more
doaj   +1 more source

Protective role for the disulfide isomerase PDIA3 in methamphetamine neurotoxicity. [PDF]

open access: yesPLoS ONE, 2012
Methamphetamine abuse continues to be a worldwide problem, damaging the individual user as well as society. Only minimal information exists on molecular changes in the brain that result from methamphetamine administered in patterns typical of human ...
Gurudutt Pendyala   +2 more
doaj   +1 more source

Methamphetamine contamination in residential properties and their remediation in Queensland, Australia

open access: yesForensic Science International: Reports, 2023
The high use rate for methamphetamine in Australia has led to the emergence of local clandestine production. Contamination of the properties being used for methamphetamine production or consumption poses adverse health risks to occupants, and thus ...
Jianfa Gao   +6 more
doaj   +1 more source

Partial MHC/neuroantigen peptide constructs: a potential neuroimmune-based treatment for methamphetamine addiction. [PDF]

open access: yesPLoS ONE, 2013
Relapse rates following current methamphetamine abuse treatments are very high (∼40-60%), and the neuropsychiatric impairments (e.g., cognitive deficits, mood disorders) that arise and persist during remission from methamphetamine addiction likely ...
Jennifer M Loftis   +3 more
doaj   +1 more source

SYNTHESIS, CHARACTERIZATION AND APPLICATION OF MEETHAMPHETAMINE – IMPRINTED POLYMERIC SOLID-PHASE

open access: yesThe Iraqi Journal of Agricultural science, 2023
This study was determine methamphetamine by the addition to the glycidyl methacrylate (GMA) monomer resulting from bulk polymerization formation. To acquire the highest adsorption capacity, molar ratios of the template, monomer, and cross-linking agent,
Y. K. Al-Bayati
doaj   +1 more source

Underlying Mechanism of Combined Effect of Methamphetamine and Morphine on Lethality in Mice and Therapeutic Potential of Cooling

open access: yesJournal of Pharmacological Sciences, 2005
An increase in polydrug abuse is a major problem worldwide. A previous study showed that coadministration of methamphetamine and morphine induced lethality in rodents and humans.
Mizuho Namiki   +4 more
doaj   +1 more source

ANKS1B in the Nucleus Accumbens Controls Escalated Cocaine Self‐Administration via Regulating CBP‐FoxO3 Complex

open access: yesAdvanced Science, EarlyView.
ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang   +15 more
wiley   +1 more source

A mindfulness-based, stress and coping model of craving in methamphetamine users.

open access: yesPLoS ONE, 2021
There is increasing interest in the role of mindfulness and mindfulness-based interventions to optimize recovery from a substance use disorder (SUD). However, relatively little is known about the theory-based psychological and social pathways whereby ...
Massy Mutumba   +5 more
doaj   +1 more source

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