Results 21 to 30 of about 53,967 (290)

Effect of Methamphetamine on Spectral Binding, Ligand Docking and Metabolism of Anti-HIV Drugs with CYP3A4. [PDF]

open access: yesPLoS ONE, 2016
Cytochrome P450 3A4 (CYP3A4) is the major drug metabolic enzyme, and is involved in the metabolism of antiretroviral drugs, especially protease inhibitors (PIs).
Anantha R Nookala   +7 more
doaj   +1 more source

Effects of Dopamine- and Serotonin-Related Compounds on Methamphetamine-Induced Self-Injurious Behavior in Mice

open access: yesJournal of Pharmacological Sciences, 2004
Methamphetamine induces hyperlocomotion, and high doses of methamphetamine induce self-injurious behavior (SIB) in rodents. It is well known that the monoaminergic system is involved in methamphetamine-induced behavior.
Tomohisa Mori   +3 more
doaj   +1 more source

The effects of adolescent methamphetamine exposure

open access: yesFrontiers in Neuroscience, 2015
Methamphetamine use among adolescents is a significant social and public health concern. Despite increased awareness of methamphetamine use among younger people, relatively little research has examined the effects of adolescent methamphetamine use ...
Jordan M Buck, Jessica Anne Siegel
doaj   +1 more source

Executive functioning in methamphetamine psychosis [PDF]

open access: yes, 2014
Includes bibliographical references.An association between methamphetamine dependence and neurocognitive impairment has long been established. However, there are a number of research gaps. First, while evidence suggests that the primary cognitive domains
Cotton, Sarah May
core   +1 more source

Nonnative Thiol and Aniline Methylation, Including Enantioselective Dithiol Desymmetrization, by Multicomponent Cobamide‐Dependent Methyltransferases Using Unactivated Methyl Donors

open access: yesAngewandte Chemie, EarlyView.
Mixed MtaABC/MtgABC methyltransferase systems were developed for non‐native thiol and aniline methylation using the unactivated methyl donors methanol and glycine betaine. The platform enabled site‐selective and enantioselective methylation with turnover number up to 6000, representing the first enantioselective non‐native catalysis by cobamide ...
Amardeep Kumar   +3 more
wiley   +2 more sources

Methamphetamine administration increases hepatic CYP1A2 but not CYP3A activity in female guinea pigs.

open access: yesPLoS ONE, 2020
Methamphetamine use has increased over the past decade and the first use of methamphetamine is most often when women are of reproductive age. Methamphetamine accumulates in the liver; however, little is known about the effect of methamphetamine use on ...
Jia Yin Soo   +6 more
doaj   +1 more source

Methamphetamine-induced encephalopathy in the absence of hyperammonemia

open access: yesBMC Psychiatry, 2023
Background Methamphetamine is an addictive drug with various effects on the neurotransmitters in the central nervous system. Methamphetamine-induced encephalopathy in the absence of hyperammonemia presents a unique challenge in a clinical setting ...
Jessica M Rabbany   +4 more
doaj   +1 more source

Closed‐Loop Recyclable Solid Polymer Electrolytes via Dynamic Lipoate Cross‐Linking

open access: yesAngewandte Chemie, EarlyView.
A visible‐light‐driven, closed‐loop recyclable solid polymer electrolyte is built from a bio‐derived lipoate cross‐linker, poly(ethylene glycol) bis(lipoate) (PEG‐LP2), synthesized from α‐lipoic acid. Dynamic disulfide exchange enables efficient DBU‐catalyzed depolymerization and photo‐repolymerization, regenerating membranes that retain high ionic ...
Qian Huang   +6 more
wiley   +2 more sources

Protective role for the disulfide isomerase PDIA3 in methamphetamine neurotoxicity. [PDF]

open access: yesPLoS ONE, 2012
Methamphetamine abuse continues to be a worldwide problem, damaging the individual user as well as society. Only minimal information exists on molecular changes in the brain that result from methamphetamine administered in patterns typical of human ...
Gurudutt Pendyala   +2 more
doaj   +1 more source

Methamphetamine use and HIV risk among severely mentally ill inpatients [PDF]

open access: yes, 2013
Includes bibliographical references.Sub-Saharan Africa accounts for 69% of the global HIV burden. Due to a variety of social, economic and behavioural factors, mentally ill patients are more likely to engage in high risk sexual behaviours.
Moodley, Aneshree
core   +1 more source

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