Results 21 to 30 of about 110,845 (343)

Effect of Methamphetamine on Spectral Binding, Ligand Docking and Metabolism of Anti-HIV Drugs with CYP3A4. [PDF]

open access: yesPLoS ONE, 2016
Cytochrome P450 3A4 (CYP3A4) is the major drug metabolic enzyme, and is involved in the metabolism of antiretroviral drugs, especially protease inhibitors (PIs).
Anantha R Nookala   +7 more
doaj   +1 more source

Effects of methamphetamine on locomotor activity and thalamic gene expression in leptin-deficient obese mice [PDF]

open access: yes, 2017
Leptin is an adipose-derived hormone that regulates energy balance. Leptin receptors are expressed in extrahypothalamic sites and several reports showed that leptin can influence feeding and locomotor behavior via direct actions on dopaminergic neurons ...
Bisagno, Veronica   +3 more
core   +2 more sources

Protective role for the disulfide isomerase PDIA3 in methamphetamine neurotoxicity. [PDF]

open access: yesPLoS ONE, 2012
Methamphetamine abuse continues to be a worldwide problem, damaging the individual user as well as society. Only minimal information exists on molecular changes in the brain that result from methamphetamine administered in patterns typical of human ...
Gurudutt Pendyala   +2 more
doaj   +1 more source

A Review of Methods Used to Detect Methamphetamine from Indoor Air and Textiles in Confined Spaces

open access: yesToxics, 2022
Methamphetamine manufacture, use, and the resulting contamination is a significant issue that affects public health, the environment, and the economy.
Gemma L. Kerry   +3 more
doaj   +1 more source

Childhood maltreatment and amygdala connectivity in methamphetamine dependence: a pilot study. [PDF]

open access: yes, 2014
IntroductionChildhood maltreatment, a well-known risk factor for the development of substance abuse disorders, is associated with functional and structural abnormalities in the adult brain, particularly in the limbic system.
Dean, Andy C   +3 more
core   +2 more sources

Methamphetamine administration increases hepatic CYP1A2 but not CYP3A activity in female guinea pigs.

open access: yesPLoS ONE, 2020
Methamphetamine use has increased over the past decade and the first use of methamphetamine is most often when women are of reproductive age. Methamphetamine accumulates in the liver; however, little is known about the effect of methamphetamine use on ...
Jia Yin Soo   +6 more
doaj   +1 more source

Methamphetamine-induced encephalopathy in the absence of hyperammonemia

open access: yesBMC Psychiatry, 2023
Background Methamphetamine is an addictive drug with various effects on the neurotransmitters in the central nervous system. Methamphetamine-induced encephalopathy in the absence of hyperammonemia presents a unique challenge in a clinical setting ...
Jessica M Rabbany   +4 more
doaj   +1 more source

The effects of adolescent methamphetamine exposure

open access: yesFrontiers in Neuroscience, 2015
Methamphetamine use among adolescents is a significant social and public health concern. Despite increased awareness of methamphetamine use among younger people, relatively little research has examined the effects of adolescent methamphetamine use ...
Jordan M Buck, Jessica Anne Siegel
doaj   +1 more source

Substance Use Among Lesbian, Gay, and Bisexual Clients Entering Substance Abuse Treatment: Comparisons to Heterosexual Clients [PDF]

open access: yes, 2015
Objective: This study evaluated whether sexual orientation-specific differences in substance use behaviors exist among adults entering substance abuse treatment. Method: Admissions records (July 2007–December 2009) were examined for treatment programs in
Flentje, Annesa   +2 more
core   +3 more sources

Methamphetamine contamination in residential properties and their remediation in Queensland, Australia

open access: yesForensic Science International: Reports, 2023
The high use rate for methamphetamine in Australia has led to the emergence of local clandestine production. Contamination of the properties being used for methamphetamine production or consumption poses adverse health risks to occupants, and thus ...
Jianfa Gao   +6 more
doaj   +1 more source

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