Results 51 to 60 of about 53,967 (290)

Association between genotype of the serotonin transporter-linked polymorphic region of the serotonin transporter gene and age of onset of methamphetamine use: a preliminary analysis

Frontiers in Psychiatry, 2010
Early-onset methamphetamine use increases the lifetime prevalence of methamphetamine dependence. An earlier onset of methamphetamine use leads to greater damage to the terminal ends of serotonin neurons, more reduction in serotonin transporter (5-HTT ...
Bankole A Johnson, Ahmed M Elkashef, Nassima Ait-Daoud, Chamindi Seneviratne, Roberta C Kahn, Shou-Hua Li, Daniel A Bloch, Tyson H Holmes, Xin-Qun Wang, Ming D Li, Francis J Vocci, Jr.   +10 more
doaj   +1 more source

Conversion of Methamphetamine to N-Methyl-Methamphetamine in Formalin Solutions [PDF]

Journal of Analytical Toxicology, 2005
Embalming is common, and yet it can create problems for the forensic scientist if a drug has been the cause of death and if this drug is also reactive toward the embalming fluid. Previous studies have focused on the amines such as nortriptyline, desipramine, and fenfluramine.
Padma S, Tirumalai, Diaa M, Shakleya, Peter M, Gannett, Patrick S, Callery, Tina M, Bland, Timothy S, Tracy   +5 more
openaire   +2 more sources

The narrative accounts of recovering drug users [PDF]

, 2010
This study aims to provide pertinent information regarding the widespread use of methamphetamine occurring in South Africa. This study explores how individuals who were addicted to crystal methamphetamine (CM) create meaning of their experiences of ...
Adams, Chantal
core   +1 more source

Prior Methamphetamine Use Disorder History Does Not Impair Interoceptive Processing of Soft Touch in HIV Infection [PDF]

, 2021
INTRODUCTION: Interoception, defined as the sense of the internal state of one's body, helps motivate goal-directed behavior. Prior work has shown that methamphetamine (METH) use disorder is associated with altered interoception, and that this may ...
Ellis, Ronald J, Amanda Bischoff-Grethe, Center, Translational Methamphetamine AIDS Research, Martin P. Paulus, Igor Grant, Tapert, Susan F, Grant, Igor, Paulus, Martin P, Susan F. Tapert, Bischoff-Grethe, Amanda, Ronald J. Ellis, Translational Methamphetamine AIDS Research Center (TMARC), Translational Methamphetamine AIDS Research Center (TMARC) Translational Methamphetamine AIDS Research Center (TMARC)   +12 more
core   +1 more source

Pharmacology of amphetamine-type designer drugs [PDF]

, 2013
In this thesis project, we studied the pharmacology of long-known psychostimulants and of novel amphetamine-type designer drugs in vitro. On the basis of the pharmacological characterization, we focused on the drug effects in humans, investigating the ...
Simmler, Linda
core   +1 more source

Metabolic fate of drugs of abuse and new psychoactive substances: A pilot study on a novel workflow using a zebrafish embryo model combined with human microdosing

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study was to develop a novel workflow to identify human urine biomarkers for drugs of abuse and new psychoactive substances. Metabolites of amphetamine, cocaine, LSD, MDMA, methamphetamine, THC, MDMB‐CHMICA, and MDPPP were first identified in a zebrafish embryo (ZE) metabolism study followed by comparison to most abundant human ...
Simon K. Wellenberg, Tanja M. Gampfer, Lea Wagmann, Philip Schippers, Jennifer Herrmann, Rolf Müller, Folker Westphal, Markus R. Meyer   +7 more
wiley   +1 more source

Pattern of Methamphetamine Use and the Time Lag to Methamphetamine Dependence [PDF]

Journal of Addiction Medicine, 2018
Objectives: Use of methamphetamine (MA) commonly co-occurs with the use of other substances. The present study aims to examine substance initiation patterns of other substances, including alcohol, nicotine, inhalants, and cannabis (OTH), in MA users and its consequence on the time lag of MA dependence.
Pongkwan, Yimsaard, Michael M, Maes, Viroj, Verachai, Rasmon, Kalayasiri   +3 more
openaire   +2 more sources

Tackling methamphetamine: indicators and progress report October 2012 [PDF]

, 2012
This report provides a progress update on the records changes against the Action Plan\u27s baseline data, and details progress on the Action Plan\u27s activities.When the Action Plan was launched, Chief Executives from DPMC, Health, Customs, Justice ...

core  

Development of a nalmefene formulation suitable for a community‐use auto‐injector

British Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano, Manjunath S. Shet, Hugh Huang, Ronnie Ortiz, Garth T. Whiteside, Glen Apseloff, Stephen C. Harris   +6 more
wiley   +1 more source

Gray-matter structure in long-term abstinent methamphetamine users

BMC Psychiatry, 2020
Background Previous studies of brain structure in methamphetamine users have yielded inconsistent findings, possibly reflecting small sample size and inconsistencies in duration of methamphetamine abstinence as well as sampling and analyses methods. Here
Lili Nie, Zeyong Zhao, Xiantao Wen, Wei Luo, Tao Ju, Anlian Ren, Binbin Wu, Jing Li   +7 more
doaj   +1 more source