Toxicity of Methylated Bismuth Compounds Produced by Intestinal Microorganisms to Bacteroides thetaiotaomicron, a Member of the Physiological Intestinal Microbiota [PDF]
Journal of Toxicology, 2011 Methanoarchaea have an outstanding capability to methylate numerous metal(loid)s therefore producing toxic and highly mobile derivatives. Here, we report that the production of methylated bismuth species by the methanoarchaeum Methanobrevibacter smithii,
Beatrix Bialek +4 more
doaj +4 more sources
The phylogenetic analysis and putative function of lysine 2,3-aminomutase from methanoarchaea infers the potential biocatalysts for the synthesis of β-lysine [PDF]
Journal of Microbiology, Immunology and Infection, 2013 β-amino acids play important biological roles as precursors in the biosynthesis of antibiotics, anticancer agents, neurotransmitters, and other high molecular weight polymers. Microbial cells and enzymes from extreme environments offer new opportunities for biocatalysis and biotransformations as a result of their extreme stability.
Mei-Chin Lai
exaly +4 more sources
Comparison of Enzymatic Traits between Native and Recombinant Glycine Sarcosine N-Methyltransferase from Methanohalophilus portucalensis FDF1T. [PDF]
PLoS ONE, 2016 The halophilic methanoarchaeon Methanohalophilus portucalensis FDF1T possesses the ability to synthesize the osmolyte betaine from its precursor, glycine, in response to extracellular salt stress through a three-step transmethylation process. Analysis of
Shu-Jung Lai, Yu-Chen Deng, Mei-Chin Lai
doaj +4 more sources
Methanosarcina Spherical Virus, a Novel Archaeal Lytic Virus Targeting Methanosarcina Strains [PDF]
Journal of Virology, 2017 A novel archaeal lytic virus targeting species of the genus Methanosarcina was isolated using Methanosarcina mazei strain Go1 as the host. Due to its spherical morphology, the virus was designated Methanosarcina spherical virus (MetSV).
Anne Kupczok +2 more
exaly +3 more sources
Identification of Enzymes Homologous to Isocitrate Dehydrogenase That Are Involved in Coenzyme B and Leucine Biosynthesis in Methanoarchaea [PDF]
Journal of Bacteriology, 2000 ABSTRACTTwo putativeMethanococcus jannaschiiisocitrate dehydrogenase genes, MJ1596 and MJ0720, were cloned and overexpressed inEscherichia coli, and their gene products were tested for the ability to catalyze the NAD- and NADP-dependent oxidative decarboxylation ofdl-threo-3-isopropylmalic acid,threo-isocitrate,erythro-isocitrate, and homologs ofthreo ...
Robert White
exaly +3 more sources
Identification of an Archaeal 2-Hydroxy Acid Dehydrogenase Catalyzing Reactions Involved in Coenzyme Biosynthesis in Methanoarchaea [PDF]
Journal of Bacteriology, 2000 ABSTRACT Two putative malate dehydrogenase genes, MJ1425 and MJ0490, from Methanococcus jannaschii and one from Methanothermus fervidus were cloned and overexpressed in Escherichia coli , and their gene products were tested for the ability to catalyze ...
Robert White
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Genomic Mobility: Transposons in Methanoarchaea
Methanoarchaea, a unique group of archaea, play a crucial role in the global carbon cycle through methanogenesis, a process where different carbon sources such as carbon dioxide (CO2)/hydrogen (H2), acetate, formate, methanol, and methylamines are metabolized and methane is produced.
Luise Rentz +2 more
exaly +2 more sources
Generating a Small Shuttle Vector for Effective Genetic Engineering of Methanosarcina mazei Allowed First Insights in Plasmid Replication Mechanism in the Methanoarchaeon. [PDF]
Int J Mol Sci, 2022 Due to their role in methane production, methanoarchaea are of high ecological relevance and genetic systems have been ever more established in the last two decades. The system for protein expression in Methanosarcina using a comprehensive shuttle vector
Thomsen J, Schmitz RA.
europepmc +2 more sources
Newly Established Genetic System for Functional Analysis of MetSV. [PDF]
Int J Mol Sci, 2023 The linear chromosome of the Methanosarcina spherical virus with 10,567 bp exhibits 22 ORFs with mostly unknown functions. Annotation using common tools and databases predicted functions for a few genes like the type B DNA polymerase (MetSVORF07) or the ...
Gehlert FO +5 more
europepmc +2 more sources
Methanogenic archaea isolated from Taiwan's Chelungpu fault. [PDF]
Appl Environ Microbiol, 2011 Terrestrial rocks, petroleum reservoirs, faults, coal seams, and subseafloor gas hydrates contain an abundance of diverse methanoarchaea. However, reports on the isolation, purification, and characterization of methanoarchaea in the subsurface ...
Wu SY, Lai MC.
europepmc +3 more sources