Results 41 to 50 of about 1,515,032 (291)

Engineering Escherichia coli for Poly-β-hydroxybutyrate Production from Methanol

Bioengineering, 2023
The naturally occurring one-carbon assimilation pathways for the production of acetyl-CoA and its derivatives often have low product yields because of carbon loss as CO2.
Jiaying Wang, Zhiqiang Chen, Xiaogui Deng, Qianqian Yuan, Hongwu Ma   +4 more
doaj   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

A search for 95 GHz class I methanol masers in molecular outflows

, 2012
We have observed a sample of 288 molecular outflow sources including 123 high-mass and 165 low-mass sources to search for class I methanol masers at 95 GHz transition and to investigate relationship between outflow characteristics and class I methanol ...
Chen, Xi, Gan, Cong-Gui, Ju, Bing-Gang, Shen, Zhi-Qiang, Xu, Ye   +4 more
core   +1 more source

Testing the Evolutionary Sequence of High Mass Protostars with CARMA [PDF]

, 2009
We present 1" resolution CARMA observations of the 3mm continuum and 95 GHz methanol masers toward 14 candidate high mass protostellar objects (HMPOs). Dust continuum emission is detected toward seven HMPOs, and methanol masers toward 5 sources.
Altenhoff, Beltrán, Beuther, Beuther, Bronfman, Codella, Codella, Cyganowski, Egan, Garay, Genzel, Haynes, Hildebrand, Hunter, Hunter, John M. Carpenter, Keto, Keto, Menten, Molinari, Molinari, Pandian, Perault, Qiu, Rathborne, Rathborne, Reid, Sault, Scott Schnee, Shepherd, Sridharan, Torrelles, Turner, Walmsley, Wang, Zapata, Zhang   +36 more
core   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

IN SITU DRIFTS/MS STUDIES ON THE INTERACTION OF METHANOL AND ETHYL ACETATE OVER MG-LA CATALYST [PDF]

Química Nova, 2020
The surface intermediates formed on the Mg-La catalyst (molar ratio 1:1) were studied through temperature-programmed desorption (TPD) and diffuse reflectance infrared Fourier transform spectroscopy coupled to mass spectrometry (DRIFTS-MS) using methanol (
Adão S. Gonçalves, Cristiane A. Henriques, Deborah V. Cesar   +2 more
doaj   +1 more source

Herschel observations of EXtra-Ordinary Sources (HEXOS): Methanol as a probe of physical conditions in Orion KL [PDF]

, 2011
We have examined methanol emission from Orion KL withthe Herschel/HIFI instrument, and detected two methanol bands centered at 524 GHz and 1061 GHz. The 524 GHz methanol band (observed in HIFI band 1a) is dominated by the isolated ΔJ = 0, K = −4 → −3 ...
Bell, T. A., Blake, G. A., Latter, W. B., Lis, D. C., Lord, S. D., Morris, P., Phillips, T. G., Wang, S., Zmuidzinas, J.   +8 more
core  

Mapping deuterated methanol toward L1544: I. Deuterium fraction and comparison with modeling [PDF]

, 2018
The study of deuteration in pre-stellar cores is important to understand the physical and chemical initial conditions in the process of star formation.
Bizzocchi, L., Caselli, P., Chacon-Tanarro, A., Giuliano, B. M., Lattanzi, V., Pineda, J. E., Punanova, A., Sipila, O., Spezzano, S., Vasyunin, A.   +9 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

The effects of methanol on the trapping of volatile ice components [PDF]

, 2015
The evaporation of icy mantles, which have been formed on the surface of dust grains, is acknowledged to give rise to the rich chemistry that has been observed in the vicinity of hot cores and corinos.
Adriaens, Ayotte, Backus, Bar-Nun, Blake, Bockelee-Morvan, Bolina, Bolina, Boogert, Brown, Burke, Burke, Codella, Collings, Cruikshank, Daren J. Burke, Dartois, De Jong, DelloRusso, Edridge, Ehrenfreund, Ehrenfreund, Fraser, Garozzo, Gibb, Goumans, Grim, Hagen, Herbst, Ioppolo, Jewitt, Klinger, Lellouch, Martín-Doménech, Merlin, Merlin, Mills, Notesco, Palumbo, Palumbo, Pontoppidan, Smith, Smith, Souda, Souda, Souda, Viti, Wendy A. Brown, Whittet, Wolff, Yung   +50 more
core   +1 more source