Results 61 to 70 of about 981,887 (298)

A selective electrocatalyst-based direct methanol fuel cell operated at high concentrations of methanol

, 2017
Owing to the serious crossover of methanol from the anode to the cathode through the polymer electrolyte membrane, direct methanol fuel cells (DMFCs) usually use dilute methanol solutions as fuel.
Feng, Yan, Yang, Jun, Liu, Hui
core   +1 more source

Improving the Cu/ZnO-Based Catalysts for Carbon Dioxide Hydrogenation to Methanol, and the Use of Methanol As a Renewable Energy Storage Media

Frontiers in Earth Science, 2020
Heterogeneous catalytic hydrogenation of carbon dioxide (CO2) to methanol is a practical approach to mitigating its greenhouse effect in the environment while generating good economic profits.
Ubong J. Etim, Yibing Song, Ziyi Zhong, Ziyi Zhong   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Methanol-Assisted ADMET Polymerization of Semiaromatic Amides

, 2023
A method for the acyclic diene metathesis polymerization of semiaromatic amides is described. The procedure uses second-generation Grubbs’ catalyst and N-cyclohexyl-2-pyrrolidone (CHP), a high boiling, polar solvent capable of solubilizing both monomer ...
Ashlie Martini (325826), Spencer T. Stober, Quanpeng Yang, Agostino Pietrangelo (1874449), Adam B. Burns, Lesheng Wang, Spencer T. Stober (6171632), Thomas Sun, Pamela J. Wright, Ryan T. Charlton, Adam B. Burns (1442704), Matthew T. DeRocco (15315913), Quanpeng Yang (4762359), Pamela J. Wright (15315916), Thomas Sun (483155), Ryan T. Charlton (6313193), Ashlie Martini, Manesh Gopinadhan (1422169), Lesheng Wang (13979874), Manesh Gopinadhan, Matthew T. DeRocco, Agostino Pietrangelo   +21 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Abnormal Combustion in a Methanol Fueled Engine

Abnormal combustion in methanol fueled engines was investigated using a combination of ion gap detection and pressure versus crankangle measurements. The ability to differentiate between cool flames and surface ignition is shown.
Swain, M. R.
core   +4 more sources

Visualization study on spray and ignition characteristics of high proportion methanol / PODE blended fuel

Journal of Thermal Science and Technology
With the increasingly stringent emission requirements for shipping, methanol is a promising alternative fuel. The effects of mixing ratio and ambient temperature on the spray and ignition characteristics of high proportion methanol / Polyoxymethylene ...
Rongkang SUN, Lijiang WEI, Wei SONG, Xiuwei LU, Chen HUANG   +4 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source