Results 81 to 90 of about 910,601 (311)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Selective oxidation of methane to methanol over Au/H-MOR

open access: yes, 2023
Selective oxidation of methane to methanol by molecular oxygen is a fascinating route for upgrading abundant methane resource and represents one of the most challenging reactions in chemistry due to the overwhelmingly higher reactivity of the product ...
Fangwei, Wu   +9 more
core   +1 more source

Acute oral toxicity test and determination of lethal dose (LD50) of Garcinia forbesii King leaf extract in wistar rats

open access: yesPharmaciana
Garcinia forbesii King, an endemic plant from Sumatra and Kalimantan, is traditionally used for treating skin infections and inflammation. Its potential use as a raw material for medicines needs to be supported by safety tests. The purpose of this study
Mohammad Rudiansyah   +4 more
doaj   +1 more source

Synthesis, Characterization, and Photonic Efficiency of Novel Photocatalytic Niobium Oxide Materials

open access: yesGlobal Challenges, 2017
The application of niobium oxides as photocatalytic materials for the removal of contaminants is scarcely reported in the literature. This work reports the methodology to synthesize four different mesoporous niobium oxide materials and the correlation ...
Lidiane A. Morais   +4 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

CO2 hydrogenation to methanol over zeolite-encaged mononuclear copper centers

open access: yes, 2022
The selective hydrogenation of CO2 to methanol by renewable hydrogen source represents an attractive route for CO2 recycling and carbon neutral. Stable catalysts with high activity and methanol selectivity are being hotly pursued, and current debates on ...
Landong, Li   +6 more
core   +1 more source

Development of cryoprotective media for low-temperature freezing of sterlet (Acipenser ruthenus) sperm

open access: yesRibogospodarsʹka Nauka Ukraïni, 2017
Purpose. To develop the optimum composition of a cryoprotective solution for freezing sterlet sperm with the use of new and standard constituents and compare the results of the fertilization of eggs with sperm frozen by different ways and in different ...
I. Kononenko
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Optimizing the Yield Product by Changing the Reactor Type for CO2 Hydrogenation in Methanol Synthesis with Process Simulation Software

open access: yesJournal of Chemical Engineering Research Progress
Hydrogenation is chosen as a process to reduce CO2 in the air, based on its thermodynamic stability. One of the important things to increase the yield product is by using reactor. This study aims to compare two types of reactor, i.e.
Annisa Diva Karmelia Zahra   +3 more
doaj   +1 more source

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