Results 81 to 90 of about 1,457,583 (292)

The effects of methanol on the trapping of volatile ice components [PDF]

, 2015
The evaporation of icy mantles, which have been formed on the surface of dust grains, is acknowledged to give rise to the rich chemistry that has been observed in the vicinity of hot cores and corinos.
Adriaens, Ayotte, Backus, Bar-Nun, Blake, Bockelee-Morvan, Bolina, Bolina, Boogert, Brown, Burke, Burke, Codella, Collings, Cruikshank, Daren J. Burke, Dartois, De Jong, DelloRusso, Edridge, Ehrenfreund, Ehrenfreund, Fraser, Garozzo, Gibb, Goumans, Grim, Hagen, Herbst, Ioppolo, Jewitt, Klinger, Lellouch, Martín-Doménech, Merlin, Merlin, Mills, Notesco, Palumbo, Palumbo, Pontoppidan, Smith, Smith, Souda, Souda, Souda, Viti, Wendy A. Brown, Whittet, Wolff, Yung   +50 more
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Test Results for a Novel 20 kW Two-Phase Pumped Cooling System for Aerospace Applications

Aerospace
In the EU-funded BRAVA project, technologies for a fuel cell-based power generation system for aviation are being developed. In this paper, the test results for a demonstrator of a novel two-phase pumped cooling system with 20 kW cooling capacity are ...
Henk Jan van Gerner, Tim Luten, Sigurd Scholten, Georg Mühlthaler, Marcus-Benedict Buntz   +4 more
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Improving Net Energy Efficiency of Dimethyl Ether Production Process by Methanol Dehydration

Journal of Chemical Engineering Research Progress
Dimethyl ether (DME) is a source of fuel that produces clean energy for the future. Methanol can be used as a raw material for the manufacture of DME as a natural gas that is treated for synthesis.
Astrid Eka Permatasari, Syalaisa Nanda Syabila, Hly Tyas Ajeng Kartika Dewi, Rufaidah Nilam Zahra   +3 more
doaj   +1 more source

How do methanol masers manage to appear in the youngest star vicinities and isolated molecular clumps? [PDF]

, 2007
General characteristics of methanol (CH3OH) maser emission are summarized. It is shown that methanol maser sources are concentrated in the spiral arms. Most of the methanol maser sources from the Perseus arm are associated with embedded stellar clusters ...
A. B. Ostrovskii, A. M. Sobolev, Brand, C. Henkel, Caswell, D. J. van der Walt, D. M. Cragg, Kurtz, M. A. Voronkov, M. J. Gaylard, M. S. Kirsanova, Malyshev, Menten, Minier, Minier, N. V. Pankratova, O. V. Shelemei, Pestalozzi, S. Goedhart, S. P. Ellingsen, Sobolev, Sobolev, Sobolev, T. S. Vasyunina, van der Walt, Voronkov, Xu   +26 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Testing the Evolutionary Sequence of High Mass Protostars with CARMA [PDF]

, 2009
We present 1" resolution CARMA observations of the 3mm continuum and 95 GHz methanol masers toward 14 candidate high mass protostellar objects (HMPOs). Dust continuum emission is detected toward seven HMPOs, and methanol masers toward 5 sources.
Altenhoff, Beltrán, Beuther, Beuther, Bronfman, Codella, Codella, Cyganowski, Egan, Garay, Genzel, Haynes, Hildebrand, Hunter, Hunter, John M. Carpenter, Keto, Keto, Menten, Molinari, Molinari, Pandian, Perault, Qiu, Rathborne, Rathborne, Reid, Sault, Scott Schnee, Shepherd, Sridharan, Torrelles, Turner, Walmsley, Wang, Zapata, Zhang   +36 more
core   +2 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source