Results 231 to 240 of about 6,898,244 (304)

Evolutionary Adaptation and Targeted Metabolic Engineering Synergistically Improve Methanol-Derived Single-Cell Protein Production in Pichia pastoris. [PDF]

Biotechnol J
Xie C, Zhu C, Liu J, Sun H, Xu J, Liu Q, Wang Y.   +6 more
europepmc   +1 more source

TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis

Advanced Science, EarlyView.
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu, Tiancheng Li, Yu Jin, Yixin Li, Qicheng Liu, Runzhe Fang, Luyao Qu, Xinyue Tang, Ruomei Li, Xiaoyue Zhao, Jin Hao, Bing Fang, Lunguo Xia   +12 more
wiley   +1 more source

Metabolic Engineering of Komagataella Phaffii for de Novo Synthesis of Retinol From Methanol. [PDF]

Biotechnol J
Wu Y, Liu C, Liang S, Jiang Y, Zhang X, Zhou Y, Lin Y.   +6 more
europepmc   +1 more source

RSF1‐Dependent PAR Turnover Promotes 53BP1 Liquid Condensate Formation at DNA Damage Sites

Advanced Science, EarlyView.
At sites of DNA damage, RSF1 recruits PARG to accelerate PAR turnover, triggering a switch from PAR‐driven condensates to 53BP1 condensates. This condensate transition enables p53‐dependent gene transcription and coordinates the DNA damage response.
Yungyeong Heo, Yonghyeon Kim, Nangyeong Hwang, Gwanho Sung, Sujin Jo, Yeonhu Lee, Ho‐Chul Kang, Jae‐Ho Lee, Yong Won Choi, Hyeseong Cho, Sunwoo Min   +10 more
wiley   +1 more source

Development of an Electrochemical Reactor Prototype for Biodiesel Production Powered by Photovoltaic Energy. [PDF]

ACS Omega
Rohling GF, Freire JA, Braz KMS, Oliveira Lima F, Lazarin Gallina A, Anjos T, Schumacher RF, Cabreira Soares L.   +7 more
europepmc   +1 more source

Streptococcal Mannose Phosphotransferase System Component IID Is a Novel RANK‐Binding Osteoclastogenic Factor

Advanced Science, EarlyView.
Streptococcal mannose phosphotransferase system component IID (Man‐PTSIID) is identified as a novel RANK‐binding osteoclastogenic factor. By directly binding to RANK and activating NF‐κB independently of TLR2, Man‐PTSIID drives osteoclastogenesis and inflammatory bone destruction, uncovering an unexpected microbial mechanism underlying streptococcal ...
Chaeyeon Park, Yeongkag Kwon, Yeonjin Lim, Jeong Woo Park, Hyun Jung Ji, Dongwook Lee, Jueun Lee, Sung‐Ho Yun, Sungho Jeong, Ho Seong Seo, Kun Cho, Cheol‐Heui Yun, Ok‐Jin Park, Seung Hyun Han   +13 more
wiley   +1 more source

Systematic optimization of <i>Komagataella phaffii</i> (Pichia pastoris) for high-efficiency recombinant protein production: Advancements in strain engineering, fermentation optimization, and AI-driven technologies. [PDF]

Eng Microbiol
Huang Y, Wang J, Wang A, Zheng L, Lin Y, Liang S.   +5 more
europepmc   +1 more source

Innovative Chemical Pathways for CO₂ Conversion. [PDF]

Molecules
Díaz-Sainz G, Zeng J.
europepmc   +1 more source

Fermented fruit state shapes flavor quality and methanol accumulation in kiwi wine: A comparative study of three flesh-colored kiwifruit cultivars. [PDF]

Food Chem X
Shao J, Huang S, Lou Y, Chen S, Ye X, Cheng H.   +5 more
europepmc   +1 more source

A Protocol for Lab-Scale Production of ¹³C-Labeled Yeast Extract as Internal Standard for Metabolomics and Quantification of Intracellular Metabolites. [PDF]

Curr Protoc
Cammaert M, Wouters R, van Ede J, de Hulster E, Mooiman C, van Dam P, Pabst M, van Gulik W, Daran-Lapujade P.   +8 more
europepmc   +1 more source