Results 61 to 70 of about 13,805 (215)

Genetic Code Expanded T Cell for Controllable Immunotherapy

Advanced Science, EarlyView.
Our GCE‐CAR‐T cells enables tight, dose‐dependent, and function‐preserving control of CAR expression at the translational level through amber codon suppression and genetic incorporation of ncAA. ABSTRACT Chimeric antigen receptor (CAR)‐T cell therapy has demonstrated curative potential against hematologic malignancies, but its clinical application ...
Xue Wang, Yingao Gao, Yeyu Su, Yong Wang, Tao Liu   +4 more
wiley   +1 more source

Methanogenic Conversion of 3-S-Methylmercaptopropionate to 3-Mercaptopropionate [PDF]

, 1995
Anaerobic metabolism of dimethylsulfoniopropionate, an osmolyte of marine algae, in anoxic intertidal sediments involves either cleavage to dimethylsulfide or demethylation to 3-S-methylmercaptopropionate (MMPA) and subsequently to 3-mercaptopropionate ...
Jansen, Michael,, Hansen, Theo A.,, Hansen, Theo A., Maarel, Marc J.E.C. van der,, Jansen, Michael, Maarel, Marc J.E.C. van der   +5 more
core  

The ether lipids of Methanosarcina mazei and other Methanosarcina species, compared by fast atom bombardment mass spectrometry

, 1994
The total lipids of Methanosarcina mazei accounted for 4.0% of the cell dry mass, and 90% of these were polar lipids. Nearly all of the polar fraction consisted of diether (2,3-di-O-phytanyl-sn-glycerol) and 3-hydroxydiether analogs of ...
Patel, G., Sprott, G., Dicaire, C.
core   +1 more source

H2‐dependent modulation of tetrahydromethanopterin S‐methyltransferase (Mtr complex) activity by the small protein MtrR in Methanosarcina mazei

The FEBS Journal, EarlyView.
Small protein MtrR is a regulator of the Mtr methyltransferase complex in Methanosarcina mazei. It binds specifically to the MtrA subunit and modulates Mtr activity in response to hydrogen (H2) availability. Deleting mtrR impairs growth in the presence but not absence of H2, indicating its role in directing methyl transfer toward an energy‐conserving ...
Tim Habenicht, Bjarne Hastedt, Liam Cassidy, Claudia Kießling, Andreas Tholey, Jan M. Schuller, Ruth A. Schmitz   +6 more
wiley   +1 more source

Trace elements induce predominance among methanogenic activity in anaerobic digestion

Frontiers in Microbiology, 2016
Trace elements play an essential role in all organisms due to their functions in enzyme complexes. In anaerobic digesters, control and supplementation of trace elements lead to stable and more efficient methane production processes while trace element ...
Babett Wintsche, Karin Glaser, Heike Sträuber, Florian Centler, Jan Liebetrau, Hauke Harms, Sabine Kleinsteuber   +6 more
doaj   +1 more source

Effect of ammonium concentration on methane oxidation and CO2 removal in an anaerobic biotrickling filter treating synthetic landfill gas and leachate

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 8, Page 1632-1642, August 2026.
Abstract BACKGROUND Landfill gas (LFG) and leachate are commonly treated separately through energy‐intensive processes. This study evaluated the integration of both streams in an anaerobic biotrickling filter (BTF) to achieve simultaneous methane (CH4) and carbon dioxide (CO2) removal coupled with ammonium (NH4+) transformation, and how the microbial ...
Cecilia Lizeth Alvarez‐Guzmán, Karla María Muñoz‐Páez, Alejandro Vargas, Idania Valdez‐Vazquez   +3 more
wiley   +1 more source

A CRISPRi-dCas9 System for Archaea and Its Use To Examine Gene Function during Nitrogen Fixation by Methanosarcina acetivorans

Applied and Environmental Microbiology, 2020
Genetic tools are needed to understand and manipulate the biology of archaea, which serve critical roles in the biosphere. Methanogenic archaea (methanogens) are essential for the biological production of methane, an intermediate in the global carbon ...
Ahmed E. Dhamad, D. Lessner
semanticscholar   +1 more source

Enhanced methane production in an anaerobic digestion and microbial electrolysis cell coupled system with co-cultivation of Geobacter and Methanosarcina

, 2016
The anaerobic digestion (AD) and microbial electrolysis cell (MEC) coupled system has been proved to be a promising process for biomethane production. In this paper, it was found that by co-cultivating Geobacter with Methanosarcina in an AD-MEC coupled ...
He, XH, Li, DP, Zhu, XY, Tao, Y, Li, DP (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Key Lab Environm & Appl Microbiol, Chengdu 610041, Peoples R China., Zhan, GQ, Yin, Q, Bo, T, Yang, YF, Yan, ZY   +9 more
core   +1 more source

S-layer, Surface-Accessible, and Concanavalin A Binding Proteins of Methanosarcina acetivorans and Methanosarcina mazei [PDF]

Journal of Proteome Research, 2009
The outermost cell envelope structure of many archaea and bacteria contains a proteinaceous lattice termed the surface layer or S-layer. It is typically composed of only one or two abundant, often posttranslationally modified proteins that self-assemble to form the highly organized arrays.
Deborah R, Francoleon, Pinmanee, Boontheung, Yanan, Yang, UnMi, Kin, A Jimmy, Ytterberg, Patricia A, Denny, Paul C, Denny, Joseph A, Loo, Robert P, Gunsalus, Rachel R Ogorzalek, Loo   +9 more
openaire   +2 more sources

Non-autotrophic methanogens dominate in anaerobic digesters

Scientific Reports, 2017
Anaerobic digesters are man-made habitats for fermentative and methanogenic microbes, and are characterized by extremely high concentrations of organics. However, little is known about how microbes adapt to such habitats.
Atsushi Kouzuma, Maho Tsutsumi, Shun’ichi Ishii, Yoshiyuki Ueno, Takashi Abe, Kazuya Watanabe   +5 more
doaj   +1 more source