Results 21 to 30 of about 15,591 (133)
Hong Kong Poison Information Centre: Annual report 2022
Abstract Background The Hong Kong Poison Information Centre (HKPIC) has been providing consultation services to healthcare professionals and collecting epidemiological data on poisoning in Hong Kong since 2005. Objective To analyse and report the poisoning data from HKPIC in 2022.
Tin Yat Anthony Chow +4 more
wiley +1 more source
Positional chlorination emerges as a key determinant of multitarget activity in phenylhydrazines. The para‐chloro derivative H3 shows the strongest anti‐inflammatory response, notable antibacterial activity, favorable ADMET behavior, and high COX‐2 affinity. DFT descriptors and molecular docking rationalize these substitution‐dependent effects, linking
L. Aouachria +8 more
wiley +1 more source
A biomimetic hydrogel (HPC@Gel) was developed for traumatic brain injury repair by combining oxygen‐carrying hemoglobin nanoparticles and anti‐inflammatory carbon quantum dots within a brain‐like matrix. The system alleviated hypoxia, reduced harmful neuroimmune signaling, protected neurons, supported neural regeneration, and improved neurological and ...
Peng Liu +12 more
wiley +1 more source
The antihypoxic and antioxidant activities of Pistacia lentiscus L. extract are assessed. High total phenolics and flavonoids contents are noted. Various phenolic acids and flavonoids are identified via HPLC‐MS analysis. The extract demonstrates important scavenging and reducing power, enhances mice survival under normobaric hypoxia, and reduces ...
Halima Saiah +4 more
wiley +1 more source
A new pH‐responsive poly(acrylic acid)‐Cu2+ hybrid nanoflower is developed for efficient hemoglobin adsorption. The material combines a porous flower‐like architecture with stimuli‐responsive behavior, achieving high adsorption capacity, efficient desorption, and reusability.
Merve Durmus, Nalan Özdemir
wiley +1 more source
Safety Evaluation of Bacillus Isolates From Fermented Tarhana With Probiotic Potential
Fifty‐three Bacillus strains were isolated from traditional tarhana. MALDI‐TOF MS identified the isolates within the Bacillus subtilis group. None of the isolates harbored the tested virulence genes. The isolates exhibited high tolerance to bile salts and simulated gastric conditions.
Ayşe Avcı +5 more
wiley +1 more source
DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu +6 more
wiley +1 more source
Peroxynitrite‐induced structural remodeling and aggregation of hemoglobin under nitroxidative stress
Abstract Peroxynitrite (PN), generated by the reaction of nitric oxide with superoxide, is a potent reactive nitrogen species (RNS) implicated in nitroxidative protein damage in cardiovascular and neurodegenerative diseases. Hemoglobin (Hb), the principal oxygen‐transport protein of erythrocytes, is a key intravascular scavenger and target of PN ...
Shaik Basha +3 more
wiley +1 more source
Methaemoglobinaemia: From pathophysiology to contemporary clinical management
Summary Methaemoglobin (MetHb) is an oxidised form of haemoglobin (Hb) unable to bind oxygen. Raised levels of MetHb reduce the blood's oxygen‐carrying capacity, causing potentially severe hypoxaemia and possible death. The condition arises from three main pathologies: mutations in globin genes causing Haemoglobin‐M, inherited deficiency of the enzyme ...
Alexander J. Twine, David C. Rees
wiley +1 more source

