Results 21 to 30 of about 15,591 (133)

Hong Kong Poison Information Centre: Annual report 2022

open access: yesHong Kong Journal of Emergency Medicine, Volume 33, Issue 5, October 2026.
Abstract Background The Hong Kong Poison Information Centre (HKPIC) has been providing consultation services to healthcare professionals and collecting epidemiological data on poisoning in Hong Kong since 2005. Objective To analyse and report the poisoning data from HKPIC in 2022.
Tin Yat Anthony Chow   +4 more
wiley   +1 more source

Chlorine Position Governs the Multitarget Bioactivity of Phenylhydrazines: In Vitro Antioxidant, Anti‐Inflammatory, Anti‐Tyrosinase and Antibacterial Evaluation Supported by DFT and Molecular Docking

open access: yesChemistrySelect, Volume 11, Issue 37, 6 October 2026.
Positional chlorination emerges as a key determinant of multitarget activity in phenylhydrazines. The para‐chloro derivative H3 shows the strongest anti‐inflammatory response, notable antibacterial activity, favorable ADMET behavior, and high COX‐2 affinity. DFT descriptors and molecular docking rationalize these substitution‐dependent effects, linking
L. Aouachria   +8 more
wiley   +1 more source

Biomimetic Hydrogel System Targeting S100A8 Centered Neuroimmune Crosstalk and Hypoxia Induced Neuronal Injury

open access: yesAdvanced Science, Volume 13, Issue 52, 18 September 2026.
A biomimetic hydrogel (HPC@Gel) was developed for traumatic brain injury repair by combining oxygen‐carrying hemoglobin nanoparticles and anti‐inflammatory carbon quantum dots within a brain‐like matrix. The system alleviated hypoxia, reduced harmful neuroimmune signaling, protected neurons, supported neural regeneration, and improved neurological and ...
Peng Liu   +12 more
wiley   +1 more source

Phytochemical Profiling and Biological Evaluation of Pistacia lentiscus L. grown in Chlef (Algeria): An Integrated In Vitro, In Vivo, and In Silico Study

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
The antihypoxic and antioxidant activities of Pistacia lentiscus L. extract are assessed. High total phenolics and flavonoids contents are noted. Various phenolic acids and flavonoids are identified via HPLC‐MS analysis. The extract demonstrates important scavenging and reducing power, enhances mice survival under normobaric hypoxia, and reduces ...
Halima Saiah   +4 more
wiley   +1 more source

Hemoglobin Adsorption/Desorption Studies of New Generation Stimuli Responsive Polyacrylic Acid‐Cu2+ Hybrid Nanoflowers (PAA@Cu2+ hNFs)

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
A new pH‐responsive poly(acrylic acid)‐Cu2+ hybrid nanoflower is developed for efficient hemoglobin adsorption. The material combines a porous flower‐like architecture with stimuli‐responsive behavior, achieving high adsorption capacity, efficient desorption, and reusability.
Merve Durmus, Nalan Özdemir
wiley   +1 more source

Safety Evaluation of Bacillus Isolates From Fermented Tarhana With Probiotic Potential

open access: yesFood Science &Nutrition, Volume 14, Issue 9, September 2026.
Fifty‐three Bacillus strains were isolated from traditional tarhana. MALDI‐TOF MS identified the isolates within the Bacillus subtilis group. None of the isolates harbored the tested virulence genes. The isolates exhibited high tolerance to bile salts and simulated gastric conditions.
Ayşe Avcı   +5 more
wiley   +1 more source

DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy

open access: yesMedComm, Volume 7, Issue 9, September 2026.
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu   +6 more
wiley   +1 more source

Peroxynitrite‐induced structural remodeling and aggregation of hemoglobin under nitroxidative stress

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract Peroxynitrite (PN), generated by the reaction of nitric oxide with superoxide, is a potent reactive nitrogen species (RNS) implicated in nitroxidative protein damage in cardiovascular and neurodegenerative diseases. Hemoglobin (Hb), the principal oxygen‐transport protein of erythrocytes, is a key intravascular scavenger and target of PN ...
Shaik Basha   +3 more
wiley   +1 more source

Methaemoglobinaemia: From pathophysiology to contemporary clinical management

open access: yesBritish Journal of Haematology, Volume 209, Issue 3, Page 900-910, September 2026.
Summary Methaemoglobin (MetHb) is an oxidised form of haemoglobin (Hb) unable to bind oxygen. Raised levels of MetHb reduce the blood's oxygen‐carrying capacity, causing potentially severe hypoxaemia and possible death. The condition arises from three main pathologies: mutations in globin genes causing Haemoglobin‐M, inherited deficiency of the enzyme ...
Alexander J. Twine, David C. Rees
wiley   +1 more source

METHEMOGLOBIN

open access: yesJournal of Biological Chemistry, 1925
James B. Conant, Louis F. Fieser
openaire   +1 more source

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