Results 171 to 180 of about 97,104 (253)

Stereodivergent Synthesis of C5‐α‐Substituted Linezolid Derivatives From D‐Mannitol and Structure–Antibacterial Activity Evaluation

open access: yesChirality, Volume 38, Issue 9, September 2026.
A stereodivergent route from D‐mannitol enables access to enantiopure C5‐α‐substituted linezolid analogues with full configurational control. Biological evaluation reveals that α‐substitution abolishes antibacterial activity irrespective of stereochemistry, establishing a strict steric limitation at C5 and highlighting the dominant role of substituent ...
José A. Gálvez   +3 more
wiley   +1 more source

Isolation of a Methicillin-Resistant <i>Staphylococcus pseudintermedius</i> Strain from a Domestic Dog with Vulvovaginitis: A Potential Public Health Concern? [PDF]

open access: yesAntibiotics (Basel)
Pace L   +10 more
europepmc   +1 more source

Toddlers and terriers: a One Health partnership to combat antimicrobial resistance

open access: yes
Journal of Small Animal Practice, EarlyView.
M. Prodanuk, F. Emdin
wiley   +1 more source

Active Free Radical Cold Atmosphere Plasma Promotes Healing of Diabetes Foot Ulcer: Mechanism and Challenge

open access: yesDiabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Background Diabetic foot ulcers (DFUs) have become an important cause of disability and death in patients with diabetes. Traditional therapies are prone to problems such as recurrence and drug resistance, which result in unsatisfactory healing effects for DFUs.
Yiran Wang   +4 more
wiley   +1 more source

Comparing Chemoenzymatic and Conventional Synthetic Strategies to Wall Teichoic Acid Peptidoglycan Fragments

open access: yesIsrael Journal of Chemistry, Volume 66, Issue 5, September 2026.
The Gram‐positive bacteria, Staphylococcus aureus, contain wall teichoic acid (WTA, a glycopolymer (green and yellow)) is a virulence factor in their cell wall. Synthesis of the peptidoglycan‐(PG)‐WTA conjugate (blue squares) was developed via the phospho‐donor and PG acceptor (structures at the bottom right).
Min Liu   +2 more
wiley   +1 more source

Intelligent design of artificial biocatalyst for biomedical diseases

open access: yesJournal of Intelligent Medicine, Volume 3, Issue 3, Page 220-249, September 2026.
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang   +3 more
wiley   +1 more source

Antibacterial Effect of the In Vitro Interaction Between Clotrimazole and Chlorhexidine Against Staphylococcus pseudintermedius With Known Resistance Patterns Isolated From Canine Pyoderma

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
The 2:1 chlorhexidine–clotrimazole combination demonstrated enhanced antibacterial activity against canine Staphylococcus pseudintermedius isolates, including resistant strains. Reduced MIC values, predominantly additive interactions and absence of antagonism support its use as a promising topical strategy for canine pyoderma management.
Brenda Gallegos‐Torres   +3 more
wiley   +1 more source

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