Results 1 to 10 of about 34,465 (168)
Brazilian Journal of Infectious Diseases, 2016 Acute bacterial skin and skin structure infections are caused mainly by Gram-positive bacteria which are often treated with intravenous vancomycin, daptomycin, or linezolid, with potential step down to oral linezolid for outpatients.
Alejandro Ortiz-Covarrubias +9 more
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Linezolid-induced Black Hairy Tongue
Journal of Association of Pulmonologist of Tamil NaduLinezolid is an effective multidrug-resistant anti-tubercular drug. However, the use of linezolid has been associated with multiple side effects. One of the rare side effects is linezolid-induced black hairy tongue, which is a benign and self-limiting ...
M. Natraj, T. Anbarasan
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Medical Journal of Dr. D.Y. Patil VidyapeethObjective Linezolid is an important antimicrobial agent which is active against multidrug-resistant Gram-positive cocci. Methicillin-resistant Staphylococcus aureus (MRSA) cause life-threatening infection, with narrow therapeutic options including ...
Km. Sangita +3 more
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Clinical and Translational ScienceThe objective of this study was to develop a population pharmacokinetic model for linezolid in hematooncological patients with sepsis, and to propose dosing optimization based on pharmacokinetic covariates that would lead to improved achievement of the ...
Alžběta Zavřelová +9 more
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Risk factors for linezolid - induced haematological toxicity in patients: a retrospective study
Journal of Infection in Developing CountriesIntroduction: This single-center, observational cohort study aimed to investigate the risk factors associated with linezolid-induced hematological toxicity by analyzing the linezolid trough concentration (Cmin) obtained from patients undergoing ...
Kai Mo +9 more
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The protective role of vitamin C against linezolid-induced hepato-renal toxicity in a rat model
Frontiers in PharmacologyThis study investigated the protective effects of vitamin C against linezolid-induced hepatotoxicity and nephrotoxicity in rats using biochemical, histopathological, and immunohistochemical methods. Twenty-four rats were divided into four groups: control,
Shaimaa M. Azzam +10 more
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Protective Effect of Exogenous Adenosine Triphosphate Against Ocular Toxicity of Linezolid in Rats
LifeLinezolid, a synthetic antimicrobial agent, may induce oxidative damage in ocular tissues, particularly in the optic nerve. Adenosine triphosphate (ATP) is involved in the production of antioxidants that scavenge and neutralize reactive oxygen species ...
Cenap Mahmut Esenulku +8 more
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Evaluation of the stability of linezolid in aqueous solution and commonly used intravenous fluids
Drug Design, Development and Therapy, 2017 Rachel Taylor, Bruce Sunderland, Giuseppe Luna, Petra Czarniak School of Pharmacy, Faculty of Health Sciences, Curtin University, Bentley, WA, Australia Purpose: The aim was to evaluate the stability of linezolid in commonly used intravenous fluids and
Taylor R +3 more
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