Results 11 to 20 of about 63,855 (231)
Drug Resistance Updates, 2018 Vancomycin-resistant enterococci (VRE) are important nosocomial pathogens. Invasive VRE infections are difficult to treat since common therapeutic options including ampicillin and glycopeptides often fail.
Jennifer K Bender +2 more
exaly +2 more sources
Evaluation of the stability of linezolid in aqueous solution and commonly used intravenous fluids [PDF]
Drug Design, Development and Therapy, 2017 Rachel Taylor, Bruce Sunderland, Giuseppe Luna, Petra Czarniak School of Pharmacy, Faculty of Health Sciences, Curtin University, Bentley, WA, Australia Purpose: The aim was to evaluate the stability of linezolid in commonly used intravenous fluids and
Taylor R +3 more
doaj +2 more sources
Frontiers in Pharmacology, 2023 Linezolid combined with rifampicin has shown excellent clinical outcomes against infection by multi-resistant Gram-positive bacteria. However, several studies have indicated that rifampicin reduces the plasma concentration of linezolid in patients with ...
Pan Yan +4 more
doaj +1 more source
Bedaquiline–Pretomanid–Linezolid Regimens for Drug-Resistant Tuberculosis
New England Journal of Medicine, 2022 BACKGROUND The bedaquiline–pretomanid–linezolid regimen has been reported to have 90% efficacy against highly drug-resistant tuberculosis, but the incidence of adverse events with 1200 mg of linezolid daily has been high.
F. Conradie +27 more
semanticscholar +1 more source
Parallel evolution of linezolid-resistant Staphylococcus aureus in patients with cystic fibrosis
Microbiology Spectrum, 2023 Linezolid is an antibiotic used to treat serious Staphylococcus aureus infections. Resistance to linezolid is considered rare but could emerge with repeated dosing.
Nicholas J. Pitcher +13 more
doaj +1 more source
Journal of Global Antimicrobial Resistance, 2022 : Objectives: Linezolid-dependent growth has contributed to wide dissemination of Staphylococcus epidermidis in hospitals. This study aimed to characterise linezolid-resistant coagulase-negative staphylococci (CoNS) isolates and the possibility of ...
Fei Jiang +6 more
doaj +1 more source
Linezolid for the Treatment of Urinary Tract Infections Caused by Vancomycin-Resistant Enterococci
Pharmacy, 2021 Vancomycin-resistant enterococci (VRE) account for a large proportion of hospital-acquired infections. Determining optimal treatment of VRE urinary tract infections (UTIs) is challenging.
Mary Joyce Wingler +5 more
doaj +1 more source
PLOS Global Public Health, 2023 Bedaquiline (B), pretomanid (Pa) and linezolid (L) are key components of new regimens for treating rifampicin-resistant tuberculosis (TB). However, there is limited information on the global prevalence of resistance to these drugs and the impact of ...
J. Timm +9 more
semanticscholar +1 more source
Clinical Infectious Diseases, 2023 Background Effectiveness, safety, tolerability, and adherence are critical considerations in shifting to shorter tuberculosis (TB) regimens. Novel 6-month oral regimens that include bedaquiline (B), pretomanid (Pa), and linezolid (L), with or without a ...
Tasnim Hasan +15 more
semanticscholar +1 more source
Saudi Pharmaceutical Journal, 2022 Linezolid is an oxazolidinone antibiotic. Linezolid-associated lactic acidosis has been reported in 6.8% of linezolid-treated patients. Lactic acidosis is associated with poor clinical outcomes, with high blood lactate levels resulting in organ ...
Naiju Zhang +5 more
doaj +1 more source