Results 41 to 50 of about 41,531 (223)

On‐site pilot‐scale advanced oxidation pretreatment of hospital wastewater: assessment of pharmaceuticals, pathogens, antibiotic resistance genes and acute ecotoxicity

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Hospital premises generate wastewater containing a wide spectrum of contaminants, such as pharmaceutically active compounds (PhACs), antibiotic resistance genes (ARGs) and pathogenic microorganisms, whilst plenty of them are classified under the antibiotic resistant bacteria (ΑRΒ) category.
Andreas Kaliakatsos, Iosifina Gounaki, Spyros Dokianakis, Georgios Gkotsis, Maria‐Christina Nika, Eleni Aleiferi, Athanasios S Stasinakis, Nikos Katsarakis, Nikolaos S Thomaidis, Thrassyvoulos Manios, Michalis S Fountoulakis, Danae Venieri   +11 more
wiley   +1 more source

Genomic and Phenotypic Analysis of Linezolid-Resistant Staphylococcus epidermidis in a Tertiary Hospital in Innsbruck, Austria

Microorganisms, 2021
Whole genome sequencing is a useful tool to monitor the spread of resistance mechanisms in bacteria. In this retrospective study, we investigated genetic resistance mechanisms, sequence types (ST) and respective phenotypes of linezolid-resistant ...
Silke Huber, Miriam A. Knoll, Michael Berktold, Reinhard Würzner, Anita Brindlmayer, Viktoria Weber, Andreas E. Posch, Katharina Mrazek, Sarah Lepuschitz, Michael Ante, Stephan Beisken, Dorothea Orth-Höller, Johannes Weinberger   +12 more
doaj   +1 more source

Cefdinir reprograms Gram‐positive bacteria to synergize with lysozyme against superbugs

mLife, EarlyView.
Abstract Multidrug‐resistant (MDR) bacteria pose a critical global health threat, urgently requiring solutions. Cefdinir, the highest‐selling third‐generation cephalosporin but one now facing clinical obsolescence due to escalating resistance, is conventionally classified as a nascent cell wall synthesis inhibitor.
Qi Zhang, Yang Yang, Shuqi Li, Zhao Liu, Chun‐Kit Lee, Chi‐Bun Ko, Qian Zhao   +6 more
wiley   +1 more source

A possible interaction between linezolid and digoxin: A case report of therapeutic drug monitoring

Saudi Pharmaceutical Journal, 2020
Drug-drug interactions lead to altered clinical effects, including adverse reactions. Therapeutic drug monitoring of digoxin is necessary due to its narrow therapeutic range.
Zhu Yulin, Kong Lingti, Gao Shan, Zhang Yong   +3 more
doaj   +1 more source

The Mycobacterium tuberculosis Rv0132c Gene Product Mtb‐FGD2 Can Act as an F420‐Dependent Glucose Dehydrogenase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The role of the cell envelope‐associated Rv0132c/FGD2 from Mycobacterium tuberculosis has long been a subject of debate. Importantly, FGD2 is found only in pathogenic mycobacteria, making it a potential drug target. While some suggest it functions as a glucose‐6‐phosphate dehydrogenase, others propose it acts instead as an F420‐dependent ...
Adewale V. Aderemi, Matthew Snee, Richard B. Tunnicliffe, Linus O. Johanissen, Matthew J. Cliff, Colin W. Levy, Derren J. Heyes, Marina Golovanova, Thomas A. Jowitt, Sam Hay, Andrew W. Munro, Jonathan P. Waltho, David Leys   +12 more
wiley   +1 more source

Innovative methods for the diagnosis and treatment of implant-associated infections [PDF]

, 2009
Indwelling devices and prosthesis are increasingly used in modern medicine practices. Failures of prosthetic joint devices constitute an important complication. Especially, the management of patients with a septic failure is characterized by difficulties
Baldoni, Daniela
core   +1 more source

Enterococcus faecalis and Endodontic Treatment Failure: A Qualitative Systematic Review of Its Role and Elimination Strategies

Australian Endodontic Journal, EarlyView.
ABSTRACT The aim of this study was to synthesize evidence on the influence of Enterococcus faecalis on endodontic treatment failure and strategies for its elimination. This study followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines and was registered in PROSPERO (CRD420251022741).
Francine Santos Fernandes de Lima, Analia Gabriella Borges Ferraz Facury   +1 more
wiley   +1 more source

Impact of Gentamicin‐Impregnated Collagen Sponge on the Incidence of Access Related Infections After Full‐Support Microaxial Flow Pump Therapy

Artificial Organs, EarlyView.
Local application of gentamicin for wound closure after full‐support microaxial flow pump therapy. ABSTRACT Background Surgically implanted microaxial flow pumps (mAFP) are increasingly used for cardiogenic shock treatment. Standard mAFP explantation is performed bedside with a shortening of the vascular prosthesis, which may represent a potential ...
Gaik Nersesian, Maximilian Rauch, Daniel Lewin, Leonard Pitts, Julius Kaemmel, Anna Stegmann, Julia Stein, Yuriy Hrytsyna, Felix Schoenrath, Volkmar Falk, Evgenij Potapov, Pia Lanmueller   +11 more
wiley   +1 more source

Fosfomycin Enhances the Inhibition Ability of Linezolid Against Biofilms of Vancomycin-Resistant Enterococcus faecium in vitro

, 2023
Jie Chi,1 Yaowen Li,2,3 Na Zhang,2,3 Huiping Liu,2,3 Zhifeng Chen,1 Jiabin Li,4 Xiaohui Huang2,3 1Department of Pharmacy, Tongling Municipal Hospital, Tongling, Anhui, People’s Republic of China; 2Department of Basic and Clinical Pharmacology, School of ...
Liu H, Li Y, Li J, Chen Z, Huang X, Zhang N, Chi J   +6 more
core  

Characterization of In Vitro Resistance to Linezolid in Mycobacterium abscessus

Microbiology Spectrum, 2023
Single-step selection of Mycobacterium abscessus mutants resistant to linezolid yielded high-level resistance at a low frequency that was associated with mutations in 23S rRNA or the ribosomal protein L3.
Dereje A. Negatu, Wassihun Wedajo Aragaw, Véronique Dartois, Thomas Dick   +3 more
doaj   +1 more source