Results 51 to 60 of about 63,855 (231)

Wound healing activities of polyurethane modified chitosan nanofibers loaded with different concentrations of linezolid in an experimental model of diabetes

Journal of Drug Delivery Science and Technology, 2021
Diabetes is associated with impaired wound healing, making patients susceptible to chronic non-healing wounds. Nanofibers have proven to possess potential wound healing properties when nanofibers are loaded with other wound dressing materials. This study
M. Teaima, Mohamed K. Elasaly, Sami A. Omar, M. el-Nabarawi, Kamel R. Shoueir   +4 more
semanticscholar   +1 more source

Effects of a rifampicin pre-treatment on linezolid pharmacokinetics.

PLoS ONE, 2019
Linezolid is an oxazolidinone antibiotic that effectively treats methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE).
Fumiyasu Okazaki, Yasuhiro Tsuji, Yoshihiro Seto, Chika Ogami, Yoshihiro Yamamoto, Hideto To   +5 more
doaj   +1 more source

Adverse drug events associated with linezolid administration: a real-world pharmacovigilance study from 2004 to 2023 using the FAERS database

Frontiers in Pharmacology
Introduction: Linezolid is an oxazolidinone antibiotic that is active against drug-resistant Gram-positive bacteria and multidrug-resistant Mycobacterium tuberculosis. Real-world studies on the safety of linezolid in large populations are lacking.
Fan Zou, Zhi-Wei Cui, Siyu Lou, Yingyong Ou, Chengyu Zhu, Chengjie Shu, Junyou Chen, Ruizhen Zhao, Zhu Wu, Li Wang, Zhenyong Chen, Huayu Chen, Yuanbo Lan   +12 more
semanticscholar   +1 more source

Emergence of linezolid-resistance in vancomycin-resistant Enterococcus faecium ST117 associated with increased linezolid-consumption.

International Journal of Medical Microbiology, 2021
OBJECTIVE We aim to describe the epidemiological, clinical and microbiological characteristics of the linezolid- and vancomycin- resistant Enterococcus faecium (LVRE) in a tertiary care hospital in Germany. METHODS We conducted a retrospective analysis
F. Olearo, A. Both, Cristina E. Belmar Campos, H. Hilgarth, E. Klupp, Jan Hansen, F. Maurer, M. Christner, M. Aepfelbacher, H. Rohde   +9 more
semanticscholar   +1 more source

Compassionate Use of Linezolid for Adult Taiwanese Patients with Bone and Joint Infections

, 2011
Compassionate use of linezolid for bone and joint infections has been reported and hematological adverse reactions are a cause for concern. A similar experience in Asian people has not been reported.
LU, PO-LIANG;WANG, JANN-TAY;CHEN, CHI-LONG;CHEN, WAN-CHIN;CHEN, TUN-CHIEH;HUANG, YHU-CHERING;CHANG, SHAN-CHWEN, 盧柏樑;王振泰;陳志榮;陳婉青;陳惇杰;黃玉成;張上淳   +1 more
core   +1 more source

Linezolid induced thrombocytopenia [PDF]

, 2020
Linezolid, an oxazolidinone antibiotic active against gram-positive bacteria is used in the treatment of vancomycin resistant Enterococci and MRSA. It is generally tolerated except for the 32% chance of thrombocytopenia on long term usage of linezolid. A
Muthamil, P.
core   +1 more source

Virtual Cocrystal Screening Methods as Tools to Understand the Formation of Pharmaceutical Cocrystals—A Case Study of Linezolid, a Wide-Range Antibacterial Drug

, 2021
Experimental mechanochemical screening of cocrystals with linezolid (LIN) resulted in the formation of six new crystal phases, including three neat cocrystals and three cocrystal hydrates, in addit...
Mehrnaz Khalaji, M. Potrzebowski, M. Dudek   +2 more
semanticscholar   +1 more source

Mapping the widespread distribution and transmission dynamics of linezolid resistance in humans, animals, and the environment

Microbiome
Background The rise of linezolid resistance has been widely observed both in clinical and non-clinical settings. However, there were still data gaps regarding the comprehensive prevalence and interconnections of linezolid resistance genes across various ...
Wei-Yi Shen, Chang Cai, Ning Dong, Jiawei Chen, Rong Zhang, Jiachang Cai   +5 more
semanticscholar   +1 more source

Efficacy of linezolid on Treponema pallidum, the syphilis agent: A preclinical study

EBioMedicine, 2021
Background Penicillin G, the current standard treatment for syphilis, has important drawbacks, but virtually no preclinical or clinical studies have been performed to identify viable alternatives.
Austin M. Haynes, L. Giacani, M. V. Mayans, Maria Ubals, C. Nieto, C. Pérez-Mañá, L. Quintó, Emily Romeis, O. Mitjà   +8 more
semanticscholar   +1 more source

Incidence and risk factors of linezolid-induced lactic acidosis

International Journal of Infectious Diseases, 2015
Background: The use of linezolid has increased with the emergence of multidrug-resistant bacteria. Serum lactic acidosis has been reported as a serious side effect of linezolid use, therefore we evaluated the incidence and characteristics of linezolid ...
Jae Hyoung Im, Ji Hyeon Baek, Hea Yoon Kwon, Jin-Soo Lee   +3 more
doaj   +1 more source