Results 81 to 90 of about 97,104 (253)

The Effect of Dicloxacillin Administration on Pharmacokinetics of Narrow Therapeutic Window Drugs: Phenytoin and Warfarin

Clinical Pharmacology &Therapeutics, EarlyView.
Dicloxacillin is a penicillinase‐resistant beta‐lactam antibiotic and potent activator of the Pregnane X receptor (PXR), known to induce CYP2C9, CYP2C19, and CYP3A4 activity. Clinical data suggest it reduces anticoagulation in warfarin‐treated patients and increases the risk of thromboembolic events.
Chanan Shaul, Waseem Mujahed, Ibrahim Idries, Maor Wanounou, Meir Bialer, Yoseph Caraco   +5 more
wiley   +1 more source

Clinical characteristics and outcomes of community-acquired methicillin-resistant Staphylococcus aureus septic arthritis

Southwest Respiratory and Critical Care Chronicles, 2017
Objective: We investigated the clinical characteristics, treatment patterns and outcomes of community-acquired methicillin resistant Staphylococcus aureus (CA-MRSA) septic arthritis.
Sian Yik Lim, Deepa Panikkath, Atul Ratra, Ragesh Panikkath, Kenneth Nugent   +4 more
doaj  

Comparative Phenotypic and PCR-Based Methicillin Resistance Characterization of Clinical Canine Staphylococcus pseudintermedius

Antibiotics
Background: Antimicrobial resistance in Staphylococcus pseudintermedius is an increasing concern in small animal medicine, particularly due to methicillin-resistant strains and associated multidrug resistance.
Patrik Mag, Enikő Fehér, Eszter Kaszab, Dóra Máté, Noémi Tarpataki, Ákos Jerzsele   +5 more
doaj   +1 more source

All‐in‐One Intelligent Hemostatic Sponge: Rapid Hemostasis for Non‐Compressive Wounds With Synergetic Enhanced Antibacterial Efficacy and Self‐Reporting Biodegradation

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Clinicians often concurrently tackle critical challenges including emergency hemorrhage, secondary infection, and the elusive tracking of biodegradation of conventional hemostatic agents for complex wounds. Here, we report an intelligent hemostatic sponge (spCS@AIE) by incorporating aggregation‐induced emission (AIE) nanoparticles with short‐wave ...
Zhicheng Liu, Yan Zhang, Mengmeng Wang, Ye Li, Heng Sun, Lanqiong Zhang, Xin Bai, Haicheng Wei, Zhi Wang, Hao Guan, Yanzi Xu, Dongfeng Dang, Lingjie Meng   +12 more
wiley   +1 more source

Antibacterial Hydrogel Dressing With Ca2+‐Dependent Hyaluronidase Responsiveness for Accelerating Wound Healing via On‐Demand Release of AIE Photosensitizers

Exploration, EarlyView.
This study innovates a Ca2+‐responsive hydrogel dressing that releases AIE photosensitizers on‐demand. Low Ca2+ enhances bacterial hyaluronidase (HAase) activity, degrading hyaluronic acid dressing to trigger antibacterial ROS release, while high Ca2+ inhibits HAase, preventing overdosing.
Rongwei Cui, Hao Yang, Miaomiao Kang, Zhijun Zhang, Weilin Xu, Yang Jiang, Lizhou Xu, Xiao‐Yong Zhan, Luhan Zhang, Yunsheng Xu, Dong Wang, Ben Zhong Tang, Danyang Li   +12 more
wiley   +1 more source

Evaluation of Penicillin Binding Protein 2a (PBP-2a) Latex Agglutination Assay for Rapid Identification of Methicillin-Resistant Staphylococcus aureus (MRSA) Isolated from Blood Culture Growth

Pakistan Armed Forces Medical Journal
• Objective: To determine in vitro activity of Penicillin Binding Protein 2a Latex Agglutination Assay for Rapid Identification of Methicillin-Resistant Staphylococcus aureus isolated from positive blood culture growths.
Riffat Bushra, Sakeenah Hussain Naqvi, Irfan Ali Mirza, Anam Imtiaz, Rabia Sajjad, Maria Mushtaq Gill   +5 more
doaj   +1 more source

Engineered Nature‐Based Sonosensitizer for Broad‐Spectrum Infectious Tissue Repair via Sono‐Ionic Therapy

Exploration, EarlyView.
A schematic illustration of an engineered nature‐based sonosensitizer enables early‐stage high‐power ultrasound to generate substantial reactive oxygen species for antibacterial effects and late‐stage low‐power sono‐ionic therapy for infected bone repair, infected wound biofilm therapy, and wound regeneration.
Liang Ma, Hongchuan Wang, Weidong Liang, Tao Xu, Jie Lei, Li Zhang, Shutao Gao, Xiaoyu Cai, Qian Li, Wenzhao Wang, Chuanhui Xun, Weibin Sheng, Cao Yang, Yingsong Wang   +13 more
wiley   +1 more source

Inducible Clindamycin Resistance among Staphylococci Isolated from Burn Patients

Libyan Journal of Medicine, 2009
Clindamycin has been used successfully to treat pneumonia and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus. However, inducible clindamycin resistance has been described as a cause of treatment failure of such infections. A
KS Ghenghesh, E El-Turki, K Tawil, O Shawerf, A Zorgani   +4 more
doaj  

Protective Role of Polydatin Against Vancomycin‐Induced Lung Toxicity via Oxidative Stress, Inflammation, Endoplasmic Reticulum Stress, Apoptosis, and Ferroptosis Pathways

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study aimed to evaluate whether polydatin (Poly) could eliminate the harmful effects of vancomycin (VCM) on the lungs of rats. Rats were administered VCM (200 mg/kg) and Poly (50 mg/kg), both separately and in combination, for a duration of 7 days.
Serpil Aygörmez, Sefa Küçükler, Selim Çomaklı, Hasan Şimşek, Özge Kandemir, Fatih Mehmet Kandemir, Şaban Maraşlı   +6 more
wiley   +1 more source

The mechanism of methicillin resistance [PDF]

Journal of Antimicrobial Chemotherapy, 1986
openaire   +2 more sources