Results 121 to 130 of about 82,122 (259)

Increased Pediatric Head and Neck Abscesses Following the COVID‐19 Pandemic

open access: yesThe Laryngoscope, EarlyView.
This study evaluated the impact of the COVID‐19 pandemic on pediatric head and neck abscesses at two tertiary care centers. Overall head and neck abscess incidence increased more than threefold in the post‐pandemic period compared with the pre‐pandemic period, with increases observed across all major abscess subtypes.
Marco DiBlasi   +4 more
wiley   +1 more source

The Use of Blue Light as an Antimicrobial Treatment Against Staphylococcus aureus: A Systematic Review

open access: yesLasers in Surgery and Medicine, EarlyView.
ABSTRACT Background Staphylococcus aureus (S. aureus) is a major cause of skin, wound, and device‐related infections. Blue light (405–470 nm), shows promise for treating this organism. However, the translatability, dosing parameters, safety, and effectiveness remain unclear, and no systematic review currently exists.
Alexander Idrogo‐Lam   +3 more
wiley   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva   +23 more
wiley   +1 more source

Post‐Mortem Nasal Swab Testing to Reveal Hidden Respiratory Pathogens: Unlocking Public Health Insights in Bangladesh

open access: yesMedicine Advances, EarlyView.
Respiratory deaths in Bangladesh are frequently assigned non‐specific causes because of limited diagnostic information. Through stakeholder consultations, key informant interviews, microbiologist consultations, and literature review, 11 priority respiratory pathogens were identified for potential detection using post‐mortem nasal swab testing and ...
Ridwana Maher Manna   +1 more
wiley   +1 more source

Long‐Term Outcomes of Sacral Neuromodulation Explantation: A 12‐Year Experience at a High‐Volume Tertiary Center

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Sacral neuromodulation (SNM) is a therapeutic option offered to patients with idiopathic overactive bladder (OAB) or non‐obstructive urinary retention, as an alternative treatment for refractory medical management. It allows for electrical stimulation of inhibitory circuits that modulate the micturition reflex and improve lower ...
Carly Fiorido   +10 more
wiley   +1 more source

Programming Multidomain Peptides With Molecular Frustration Into Biomolecular Condensates

open access: yesSmall, EarlyView.
De novo designed multidomain peptides (MDPs) were used to explore how molecular ordering influences peptide phase behavior. MDPs containing partially folded β‐sheets were found to form biomolecular condensates. This work introduces a new design principle for condensate formation and expand the design space beyond conventional intrinsically disordered ...
Debdatta Das   +12 more
wiley   +1 more source

Quantitative Imaging of Human Hemoglobin Binding to Staphylococcus aureus With Single‐Molecule Resolution

open access: yesSmall, EarlyView.
Single‐molecule localization microscopy is exploited to quantify the number of hemoglobin copies bound to specific receptors on S. aureus wall. This quantification supports the design of a photoactive derivative of hemoglobin able to photo‐inactivate S.
Pietro Delcanale   +10 more
wiley   +1 more source

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