Results 131 to 140 of about 21,871,524 (296)

Molecular characterization of enterotoxin genes in methicillin-resistant S. aureus isolated from food poisoning outbreaks in Egypt. [PDF]

J Health Popul Nutr, 2023
Ramadan HA, El-Baz AM, Goda RM, El-Sokkary MMA, El-Morsi RM.   +4 more
europepmc   +1 more source

Electron compensation‐gated nanomotor for immunomodulation and microenvironment remodeling in bacterial pneumonia therapy

BMEMat, EarlyView.
A nanomotor featuring an “electronic lock” via electron compensation in an Au‐Ag alloy ensures therapeutic precision. Near‐infrared light acts as a key, unlocking on‐demand Ag+ release for synergistic bactericidal action and microenvironment remodeling to potently treat bacterial pneumonia. Abstract Bacterial pneumonia treatment is severely hampered by
Chenglong Xue, Xiaoyu Zhao, Yuqian Wang, Lijin Shi, Qi Shuai   +4 more
wiley   +1 more source

Exosome‐mimetic vesicle‐encapsulated multi‐responsive antibacterial hydrogel core‐shell microneedle patch promotes scarless healing of infected wounds

BMEMat, EarlyView.
The core‐shell microneedle patch VP@FNV‐CuO2‐MN was fabricated by encapsulating n‐CuO2 in a moderately crosslinked PVA/CMCS/Borax4 hydrogel shell and VP‐loaded fibroblast membrane nanovesicles (VP@FNV) in a highly crosslinked PVA/CMCS/Borax6 hydrogel core. Upon application to an infected wound, the acidic microenvironment triggers Fenton‐like reactions
Ziwei Jiang, Huihui Zhang, Lianglong Chen, Zhangfeifan Yang, Sai Cao, Yufang He, Xiaoyang Liu, Siew Yee Wong, Xu Li, Hai Zhou, Ziyan Li, Zijun Zheng, Lei Yang   +12 more
wiley   +1 more source

Evidence of bisphosphonate-conjugated sitafloxacin eradication of established methicillin-resistant S. aureus infection with osseointegration in murine models of implant-associated osteomyelitis. [PDF]

Bone Res, 2023
Ren Y, Weeks J, Xue T, Rainbolt J, de Mesy Bentley KL, Shu Y, Liu Y, Masters E, Cherian P, McKenna CE, Neighbors J, Ebetino FH, Schwarz EM, Sun S, Xie C.   +14 more
europepmc   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

The Effect of Dicloxacillin Administration on Pharmacokinetics of Narrow Therapeutic Window Drugs: Phenytoin and Warfarin

Clinical Pharmacology &Therapeutics, EarlyView.
Dicloxacillin is a penicillinase‐resistant beta‐lactam antibiotic and potent activator of the Pregnane X receptor (PXR), known to induce CYP2C9, CYP2C19, and CYP3A4 activity. Clinical data suggest it reduces anticoagulation in warfarin‐treated patients and increases the risk of thromboembolic events.
Chanan Shaul, Waseem Mujahed, Ibrahim Idries, Maor Wanounou, Meir Bialer, Yoseph Caraco   +5 more
wiley   +1 more source

All‐in‐One Intelligent Hemostatic Sponge: Rapid Hemostasis for Non‐Compressive Wounds With Synergetic Enhanced Antibacterial Efficacy and Self‐Reporting Biodegradation

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Clinicians often concurrently tackle critical challenges including emergency hemorrhage, secondary infection, and the elusive tracking of biodegradation of conventional hemostatic agents for complex wounds. Here, we report an intelligent hemostatic sponge (spCS@AIE) by incorporating aggregation‐induced emission (AIE) nanoparticles with short‐wave ...
Zhicheng Liu, Yan Zhang, Mengmeng Wang, Ye Li, Heng Sun, Lanqiong Zhang, Xin Bai, Haicheng Wei, Zhi Wang, Hao Guan, Yanzi Xu, Dongfeng Dang, Lingjie Meng   +12 more
wiley   +1 more source

Expression of aap and icaR genes involved in biofilm production in clinical strains of Staphylococcus aureus resistant to methicillin and gentamicin

مجله علمی دانشگاه علوم پزشکی کردستان, 2018
Backgrounds and Aim: Staphylococcus aureus biofilms are involved in a multitude of serious chronic infections. Production of biofilms is a defensive-invasive process controlled and regulated by the aap and icaR genes. The expression levels of these genes
Narges Heydari, Hamed Tahmasebi, Behrooz Zeini, Sanaz Dehbashi, Mohammad Reza Arabestani   +4 more
doaj  

Nasal carriage rate, associated factors, and antimicrobial susceptibility patterns of methicillin resistance Staphylococcus aureus among pre-clinical undergraduate students at the College of Health and Medical Sciences, Haramaya University, Ethiopia

Frontiers in Public Health
BackgroundStaphylococcus aureus nasal carriage has been linked to higher rates of infection and morbidity. People with Methicillin-resistant Staphylococcus aureus can be a potential source of infection for others.
Fitsum Weldegebreal, Fitsum Weldegebreal, Kedir Urgesa, Firayad Ayele, Kasahun Bogale, Taddese Shume, Mohammed Ahmed, Sileshi Debebe, Fikru Tebeje, Haftu Asmerom, Tewodros Tesfa, Shambel Mekonnen   +11 more
doaj   +1 more source

Incidence and impact of respiratory tract infections on outcomes in patients with status epilepticus: A 20‐year longitudinal observation

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to identify the incidence of respiratory tract infections (RTIs) in a large cohort of adult patients with status epilepticus (SE) and to characterize their associations with clinical features and outcome determinants.
Sebastian Berger, Sira M. Baumann, Urs Fisch, Lisa Hert, Pascale Grzonka, Sabina Hunziker, Stephan Rüegg, Sarah Tschudin‐Sutter, Raoul Sutter   +8 more
wiley   +1 more source