Results 241 to 250 of about 106,567 (341)

Mutasynthesis and Antibiotic Activity of Mupirocin Analogues

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
A mutasynthetic strategy was developed to prepare pseudomonic acid analogues, and their antimicrobial activities were evaluated against five bacterial strains. Feeding studies with mutant strains of Pseudomonas fluorescens revealed that C7‐desepoxy‐PA‐B was metabolised to C7‐PA‐C with loss of the 8‐hydroxyl group, but no fatty acid chain extension ...
Sarah M. Husain, Luoyi Wang, Li‐Chen Han, James I. Bowen, Zhongshu Song, Felix de Courcy‐Ireland, Ashley J. Winter, Thomas J. Simpson, Paul R. Race, James Spencer, Matthew P. Crump, Christine L. Willis   +11 more
wiley   +1 more source

Bioresponsive pseudoGlucosinolates (psGSLs) Release Isothiocyanates (ITCs) in the Presence of Nitroreductases

Chemistry – A European Journal, Volume 32, Issue 25, 2 July 2026.
This work introduces the concept of pseudoglucosinolates (psGSLs) and reports the synthesis and evaluation of nitroreductase‐responsive psGSLs. These compounds represent a complementary prodrug strategy to natural glucosinolates (GSLs) for the controlled release of isothiocyanates (ITCs), enabling bio‐responsive protein labeling, as demonstrated in ...
Claire C. Jimidar, Charity S. G. Ganskow, Mervic D. Kagho, Aishi Chakrabarti, Lorenz Wiese, Michael Zollo, Ulrike Beutling, Leona C. Cesar, Julia Morud, Kamila Bugaj, Mark Brönstrup, Stephan A. Sieber, Stephan M. Hacker, Philipp Klahn   +13 more
wiley   +1 more source

Prevalence of Staphylococcus aureus and of methicillin-resistant S. aureus (MRSA) along the production chain of dairy products in north-western Greece

, 2017
Panagiotis Papadopoulos, Theofilos Papadopoulos, Apostolos S. Angelidis, Evridiki Boukouvala, Αntonios Ζdragas, Anna Papa, Christos Hadjichristodoulou, Daniel Sergelidis   +7 more
openalex   +2 more sources

Impact of Prophylactic Cefepime on Surgical Site Infection and Severe Morbidity in Patients Who Underwent Pancreaticoduodenectomy With Preoperative Biliary Drainage

Annals of Gastroenterological Surgery, Volume 10, Issue 4, Page 1133-1142, July 2026.
ABSTRACT Background Although prophylactic broad‐spectrum antibiotics can reduce postoperative complications after pancreaticoduodenectomy (PD), the optimal regimen remains uncertain. This study evaluated the impact of prophylactic cefepime (CFPM) on surgical site infection (SSI) and severe morbidity after PD with preoperative biliary drainage.
Genki Watanabe, Akihiro Murata, Yu Kasamatsu, Atsushi Ishihara, Daisuke Nagashima, Tetsuzo Tashima, Shintaro Kodai, Akishige Kanazawa, Sadatoshi Shimizu   +8 more
wiley   +1 more source

Data Mining Models in Prediction of Vancomycin-Intermediate Staphylococcus aureus in Methicillin-Resistant S. aureus (MRSA) Bacteremia Patients in a Clinical Care Setting. [PDF]

Microorganisms
Chen WC, Wang JL, Chang CC, Lin YE.
europepmc   +1 more source

Linezolid‐induced lactic acidosis in critically ill patients: A multicentre study of incidence, severity and predictors

British Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2239-2249, July 2026.
Abstract Introduction Linezolid, a synthetic oxazolidinone for resistant gram‐positive infections, is generally associated with mild adverse effects such as gastrointestinal disturbances, but more serious reactions like lactic acidosis (LA) have also been reported.
Lina Naseralallah, Bodoor Aboujabal, Zahra Noureddine, Khaled Aboujabal, Somaya Koraysh   +4 more
wiley   +1 more source

Revealing inducible clindamycin resistance in methicillin-resistant S aureus : A vital diagnostic imperative for effective treatment.

J Postgrad Med
Bawankar NS, Agrawal GN, Zodpey SS.
europepmc   +1 more source

Gymnema Saponin-Induced Lipid Flip-Flop Identifies Rigid Membrane Phenotype of Methicillin Resistant S. Aureus and Enhances It's Antibiotic Susceptibility

Santosh Kumar Sahu, Gayatree Panda, Swagatika Dehury, Himadri Gourav Behuria, Bijesh Kumar Biswal, Ashis Kumar Jena, Indrani Mohanty, Sasmita Hotta, Santosh Kumar Padhi   +8 more
openalex   +1 more source

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

British Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2028-2048, July 2026.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst, Pieter‐Jan Spiessens, Dorian Vanneste, Nada Dia, Matthias Gijsen, Isabel Spriet, Karel Allegaert, Erwin Dreesen, Anne Smits   +8 more
wiley   +1 more source

Antibacterial Effects of Essential Oils on P. aeruginosa, Methicillin-Resistant S. aureus, and Staphylococcus spp. Isolated from Dog Wounds. [PDF]

Pharmaceuticals (Basel)
Sezener Kabay MG, Inal S, Gökmen S, Ergüden VE, Fındık A, Güvenç T, Kayhan H, Güvenç D.   +7 more
europepmc   +1 more source