Results 221 to 230 of about 21,871,524 (296)

Discovery and biological evaluation of nitrofuranyl-pyrazolopyrimidine hybrid conjugates as potent antimicrobial agents targeting <i>Staphylococcus aureus</i> and methicillin-resistant <i>S. aureus</i>. [PDF]

RSC Med Chem
Saini S, Reddy GL, Gangwar A, Kour H, Nadre GG, Pandian R, Pal S, Nandi U, Sharma R, Sawant SD.   +9 more
europepmc   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Perioperative Prophylaxis in Pediatric Solid Organ Transplantation: A Baseline Stewardship Audit Using Routine Electronic Data

Transplant Infectious Disease, EarlyView.
Using routine electronic data from 164 pediatric transplants, we created reproducible stewardship measures of perioperative prophylaxis practice across transplant populations and protocol pathways. Starting prophylaxis was reliable, but continuation beyond intended stop targets—especially in abdominal transplantation—identified the clearest target for ...
Charles B. Foster, Kaitlyn Rivard, Venkatraman A. Arakoni, Blanca E. Gonzalez   +3 more
wiley   +1 more source

Clinical Significance of Organ Preservation Fluid Cultures in Pediatric Abdominal Solid Organ Transplantation

Transplant Infectious Disease, EarlyView.
In this pediatric abdominal solid organ transplant cohort, preservation fluid‐related infections were rare but occurred in infant liver transplant recipients whose preservation fluid cultures grew pathogenic organisms. These findings suggest that routine bacterial preservation fluid cultures may be most useful for identifying clinically significant ...
Hassan A. Jamal, Yong K. Kwon, Pamela L. Valentino, Jodi M. Smith, Patrick J. Healey, Zheyi Teoh   +5 more
wiley   +1 more source

Donor Dilemma: A National Simulation‐Based Case Curriculum for Teaching Donor Call Decision‐Making in Infectious Diseases Trainees

Transplant Infectious Disease, EarlyView.
An asynchronous donor‐call case‐based progressive disclosure curriculum was feasible and valued across diverse ID and TID training programs. ID and TID trainees reported improved confidence in their clinical reasoning and ability to evaluate donor‐suitability, supporting this educational approach to address a training gap.
Robert Sean Tyler, Rachel B. Colven, Alexandra G. Mills, Drew W. Charles, Ruth O. Adekunle, Divisha Sharma, Yosra Alkabab, Scott R. Curry, Ricardo M. La Hoz, Courtney E. Harris   +9 more
wiley   +1 more source

De Novo 2.2 Mb 19q13.42–q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2350-2356, October 2026.
ABSTRACT U2 small nuclear RNA auxiliary factor 2 (U2AF2) is an essential pre‐mRNA splicing factor involved in the early stages of pre‐mRNA splicing. To date, multiple individuals have been reported with predominantly heterozygous missense variants presenting intellectual disability, speech and motor delays, seizures, hypotonia, and thin or hypoplastic ...
Amanda Toledo, Sarah Araji, Weimin Bi, Seema R. Lalani   +3 more
wiley   +1 more source

Impact of cumulative glucocorticoid exposure on vancomycin clearance in hospitalized children: A retrospective cohort study

British Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3598-3610, October 2026.
Prior glucocorticoid exposure is associated with modestly increased vancomycin clearance in hospitalized children, partly mediated by renal function and inflammation and may contribute to subtherapeutic early drug exposure. Abstract Introduction Augmented renal clearance (ARC) can lead to subtherapeutic vancomycin exposure in children.
Kouki Tomari, Ruud H. J. Verstegen, Cintia Cruz, Erin Chung, Aleena Azim, Shinya Ito, Tamorah R. Lewis   +6 more
wiley   +1 more source

Natural Preservation of Refrigerated Chicken Meat Using Asphodelus microcarpus Root Extract With Machine‐Learning‐Based Shelf‐Life Prediction

eFood, Volume 7, Issue 5, October 2026.
Multifunctional Preservation & AI Prediction of Chicken Shelf Life. ABSTRACT The demand for natural and multifunctional food preservatives has increased due to growing concerns about the safety and sustainability of synthetic additives. In this study, the ethyl acetate extract of Asphodelus microcarpus roots (AmEA) was evaluated as a preservative ...
Enaam Elsomadi, Boutheina Ben Akacha, Wirginia Kukula‐Koch, Narjes Baazaoui, Monika Michalak, Miroslava Kačániová, Wojciech Koch, Sirine Choura, Mohamed Chamkha, Rania Ben Saad, Stefania Garzoli, Anis Ben Hsouna   +11 more
wiley   +1 more source

Prevalence of MRSA Bacteremia and Predictors of In‐Hospital Mortality Among Critically Ill Adults in a Tanzanian Intensive Care Unit: A Retrospective Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aims Methicillin‐resistant Staphylococcus aureus bacteremia is associated with high morbidity and mortality in critically ill patients. Management is challenging due to delays in initiating effective therapy, leading to sepsis and septic shock.
Andrew M. Bombo, Abid M. Sadiq, Anthon G. Mwingwa, Elieshiupendo M. Niccodem   +3 more
wiley   +1 more source