Results 281 to 290 of about 106,567 (341)

Optimising Therapeutic Target Attainment in Vancomycin Therapy for Patients Requiring Intermittent Haemodialysis

open access: yesNephrology, Volume 31, Issue 7, July 2026.
Optimal vancomycin dosing in dialysis patients. ABSTRACT Aims To describe the pharmacokinetics of vancomycin in patients requiring intermittent haemodialysis (iHD) and provide guidance for optimised dosing for a three‐times‐weekly post‐iHD regimen. Methods A population pharmacokinetic study using retrospectively collected data was conducted in a remote
Danny Tsai   +10 more
wiley   +1 more source

Antibiotics in Veterinary Ophthalmology: Resistance, Stewardship, and Emerging Antibiotic‐Sparing Strategies

open access: yesVeterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Antimicrobial resistance (AMR) is a growing challenge in veterinary ophthalmology, particularly in cases of bacterial keratitis, where progressive stromal infection can threaten vision and globe integrity within hours to days. This review synthesizes current evidence on pathogen distribution, antimicrobial susceptibility profiles, multidrug ...
Lionel Sebbag, Oren Pe'er
wiley   +1 more source

Discovery and Biosynthesis of the Novel Glycotetrapeptide Antibiotic Biffamycin A

open access: yesAngewandte Chemie, Volume 138, Issue 26, 22 June 2026.
Genetic de‐regulation of a silent biosynthetic pathway allowed isolation and characterisation of a novel glycopeptide antibiotic named biffamycin A, which harbours unprecedented 5‐chloro‐4‐methoxy tryptophan and 3R‐hydroxy(α‐D‐mannoysl)‐D‐lysine moieties and is bioactive against MRSA and VRSA.
Michael W. Brigham   +11 more
wiley   +2 more sources

Assessment of Ocular Surface Pathogen Susceptibility to Ultraviolet‐C (UVC) Light Treatment With a Novel Prototype Device—An In Vitro Study

open access: yesVeterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Purpose Assess in vitro efficacy of a device emitting 265 nm UVC light against bacteria isolated from veterinary infectious keratitis. Methods Twenty‐seven clinically‐derived bacterial isolates: Staphylococcus pseudintermedius (n = 10; including n = 2 methicillin‐resistant Staphylococcus pseudintermedius [MRSP]), Staphylococcus aureus (n = 1),
Oliver Joe Williams   +3 more
wiley   +1 more source

Blue LED Light Attenuates the Bacterial Bioburden in Chronic Wounds Transiently but Dose‐Dependently

open access: yesWound Repair and Regeneration, Volume 34, Issue 4, July/August 2026.
ABSTRACT Phototherapy may improve chronic wound healing through different mechanisms. We have investigated whether escalating doses of blue LED light treatment (λ = 405 nm) impact the chronic wound microbiota. Twenty‐two patients with chronic wounds were sequentially assigned to a low dose (20 J/cm2, n = 7), medium dose (60 J/cm2, n = 8), or high dose (
Frederik Plum   +7 more
wiley   +1 more source

Racemisation of Amino Acids: From Synthetic Challenge to Biological Significance

open access: yesChemBioChem, Volume 27, Issue 11, 15 June 2026.
Racemisation, once considered an undesirable synthetic side reaction, also occurs naturally in amino acids and influences biological processes. Evidence links stereochemical conversion to ageing, protein turnover, and cellular development. This review examines mechanisms, control strategies in synthesis, applications and implications in physiology ...
Othman Al Musaimi
wiley   +1 more source

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