Results 81 to 90 of about 106,567 (341)

Increased Community-Associated Infections Caused by Panton-Valentine Leukocidin–Negative MRSA, Shanghai, 2005–2014

Emerging Infectious Diseases, 2016
During 2005–2014, community-associated methicillin-resistant Staphylococcus aureus infections increased in Shanghai, China. Most infections were caused by sequence type 59 S. aureus that lacked Panton-Valentine leukocidin.
Min Li, Yanan Wang, Yuanjun Zhu, Yingxin Dai, Xufen Hong, Qian Liu, Tianming Li, Juanxiu Qin, Xiaowei Ma, Huiying Lu, Jie Xu, Michael Otto   +11 more
doaj   +1 more source

Clinical and Microbiological Determinants of Outcome in Staphylococcus aureus Bacteraemia. [PDF]

, 2010
Staphylococcus aureus bacteraemia (SAB) is commonly complicated by metastatic infection or relapse after treatment. Objectives. The study aim was to determine the role of bacterial, host, and management factors in development of complicated SAB. Methods.
Karen Walker-Bone, Lindsay, J., Llewelyn, M, Heath, I., Curtis, S., Jodi Lindsay (378699), Lindsay, J, Gillian Baker (16048691), Sally Curtis (11260241), Cubbon, M., Paul, J., John Paul (744142), Llewelyn, M., James Price (6728021), Enright, M.C., Martin Llewelyn (4461757), James Price, Mark C Enright (16048700), Walker-Bone, K., Enright, MC, Curtis, S, Mark C Enright, Martin Llewelyn, Ian Heath, Marc Cubbon, Walker-Bone, K, Price, J., Gillian Baker, Jodi Lindsay, Karen Walker-Bone (2634085), Mark C. Enright, John Paul, Baker, G., Paul, J, Cubbon, M, Sally Curtis, Ian Heath (16048694), Marc Cubbon (16048697), Enright, Mark, Baker, G, Price, J, Heath, I   +41 more
core   +1 more source

Microblasting Wound Dressings Mechanically Disrupt Polymicrobial Biofilms to Enhance Healing in Treatment‐Resistant Wounds

Advanced Science, EarlyView.
Treatment‐resistant wounds caused by polymicrobial biofilms are refractory to conventional therapies due to the dense extracellular matrices. We developed μBLAST, a microblasting wound dressing that combines MnO2‐doped biosilica and a H2O2‐releasing mesh to generate localized oxygen microbubbles that mechanically disrupt biofilms.
Yujin Ahn, Joo Hun Lee, Christian Hurd, Jiye Lee, Junggeon Park, Adam A. Markowicz, Zheyuan Zhang, Joanne Hwang, Guillermo L. Monroy, Simon A. Rogers, Woonggyu Jung, Stephen A. Boppart, Hyunjoon Kong   +12 more
wiley   +1 more source

Oxacillin magnetically targeted for the treatment of Methicillin-Resistant S. aureus infection in rats [PDF]

Acta Cirurgica Brasileira, 2017
To evaluate the effect of oxacillin bonded to magnetic nanoparticles in local infection model in rat.Twelve Wistar rats weighing 290±18g were randomly divided into four groups (n=6, each) and all rats had a magnet ring sutured on their right thighs.
Carriço, Artur da Silva, Carvalho, Juliana Fernandes, Azevedo, Ítalo Medeiros, Rocha, Keyla Borges Ferreira, Medeiros, Aldo Cunha   +4 more
openaire   +6 more sources

Pan-European early switch/early discharge opportunities exist for hospitalised patients with methicillin-resistant Staphylococcus aureus complicated skin and soft-tissue infections [PDF]

, 2014
The objective was to document pan-European real-world treatment patterns and healthcare resource use and estimate opportunities for early switch (ES) from intravenous (IV) to oral antibiotics and early discharge (ED) in hospitalised patients with ...
Solem, C.T., Haider, S., Macahilig, C., D. Simoneau, W. Lawson, C. Macahilig, Li, J.Z., Stephens, J.M., J.Z. Li, C. Eckmann, S. Haider, R. Chambers, J.M. Stephens, Simoneau, D., Eckmann, C., D. Nathwani, Lawson, W., C.T. Solem, Nathwani, D., Chambers, R., Li, J. Z.   +20 more
core   +1 more source

Inside‐Outside ROS Therapeutic Strategy Based on Piezoelectric Nano‐Urchin for Drug‐Resistant Bacteria Biofilm Infections

Advanced Science, EarlyView.
The contribution of this study lies not only in enabling effective treatment of drug‐resistant biofilm infections, but also in establishing a transferable therapeutic paradigm: Ultrasound‐triggered mechanical forces synergistically enhance piezoelectric polarization and nanozyme activity, driving functional ROS generation inside and outside biofilms ...
Xinjian Guo, Jin Yang, Mengjie An, Bingjie Lin, Tao Liu, Limin Zhang   +5 more
wiley   +1 more source

Genome sequencing defines phylogeny and spread of methicillin-resistant Staphylococcus aureus in a high transmission setting. [PDF]

, 2014
Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of nosocomial infection. Whole-genome sequencing of MRSA has been used to define phylogeny and transmission in well-resourced healthcare settings, yet the greatest burden of nosocomial ...
Thaipadungpanit, J, Holden, MTG, Cauchemez, S, Jombart, Thibaut, Tong, SY, Nickerson, Emma K, Hongsuwan, M, Cori, A, Cauchemez, Simon, Holden, Matthew T G, Parkhill, J, Köser, CU, Tong, SYC, Nickerson, EK, Day, Nicholas P, Day, NP, Holden, MT, Fraser, C, Tong, Steven Y C, Fraser, Christophe, Limmathurotsakul, Direk, Limmathurotsakul, D, Cooper, Ben, Wuthiekanun, Vanaporn, Peacock, SJ, Köser, Claudio U, Wuthiekanun, V, Cooper, BS, Cori, Anne, Parkhill, Julian, Cooper, Ben S, Day, Nicholas, Thaipadungpanit, Janjira, Peacock, Sharon J, Jombart, T, Hongsuwan, Maliwan   +35 more
core   +2 more sources

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source

Measuring the effect of enhanced cleaning in a UK hospital : a prospective cross-over study [PDF]

, 2009
Increasing hospital-acquired infections have generated much attention over the last decade. There is evidence that hygienic cleaning has a role in the control of hospital-acquired infections.
Dancer, Stephanie J., White, Liza F., Chris Robertson, Girvan E Kirsty, Lamb, Jim, Jim Lamb, Lamb Jim, Girvan, E. Kirsty, Robertson, Chris, White Liza F, Stephanie J Dancer, Liza F White, E Kirsty Girvan, Robertson Chris, Dancer Stephanie J   +14 more
core   +1 more source

De Novo 2.2 Mb 19q13.42–q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT U2 small nuclear RNA auxiliary factor 2 (U2AF2) is an essential pre‐mRNA splicing factor involved in the early stages of pre‐mRNA splicing. To date, multiple individuals have been reported with predominantly heterozygous missense variants presenting intellectual disability, speech and motor delays, seizures, hypotonia, and thin or hypoplastic ...
Amanda Toledo, Sarah Araji, Weimin Bi, Seema R. Lalani   +3 more
wiley   +1 more source