Results 41 to 50 of about 111,670 (292)

Early switch/early discharge opportunities for hospitalized patients with methicillin-resistant Staphylococcus aureus complicated skin and soft tissue infections in Brazil

Brazilian Journal of Infectious Diseases, 2019
Background: Early antibiotic switch and early discharge protocols have not been widely studied in Latin America. Our objective was to describe real-world treatment patterns, resource use, and estimate opportunities for early switch from intravenous to ...
Guilherme H. Furtado, Jaime Rocha, Ricardo Hayden, Caitlyn Solem, Cynthia Macahilig, Wing Yu Tang, Richard Chambers, Maria Lavínea Novis de Figueiredo, Courtney Johnson, Jennifer Stephens, Seema Haider   +10 more
doaj   +1 more source

Iron/Cobalt Dual‐Atom Catalyst Orchestrate Photothermal‐Chemodynamic Immunotherapy Against MRSA: Multi‐Omics Dissection in Murine and Porcine Models

Advanced Science, EarlyView.
FeCo dual‐atom catalyst (FeCo‐N‐DAC) with ultrahigh metal loading (Fe > 5.4%, Co > 4.8%) is developed for synergistic photothermal‐chemodynamic immunotherapy. FeCo‐N‐DAC penetrates deep‐seated tissues, eradicates MRSA biofilms, and reprograms immune‐inflammatory pathways via multi‐omics‐validated mechanisms.
Shihao Xu, Binge Huang, Hao Lin, Jinming Li, Zhaoxiang Lu, Qi Zhang, Jia Li, Shiping Yang, Songsong Lan, Yan Yang, Yun Feng, Xiaojun He   +11 more
wiley   +1 more source

Precise Construction of an Antimicrobial Peptide Targeting Bacterial Cell Membranes Derived From Natural Peptides

Advanced Science, EarlyView.
An AMP (P 3‐3R‐8I) based on natural peptides, which can target bacterial cell membranes, was precisely constructed via amino acid mutation. P 3‐3R‐8I exhibits antibacterial capability which could be attributed to the ability of P 3‐3R‐8I to quickly penetrate bacterial cell membranes and then to bind to bacterial DNA.
Jiaqi Huang, Bohao Liu, Xingzhuo Zhu, Deqian Qiao, Sizhe Chen, Xiaoyan Zeng, Qingqing Yang, Zihuan Wei, Yinjuan Huang, Jizhao Wang, Guangjian Zhang, Qiuyu Gong   +11 more
wiley   +1 more source

Dalbavancin was effective and safe after one year of treatment in a complicated osteoarticular infection caused by methicillin-resistant Staphylococcus aureus [PDF]

, 2021
Mayra Matesanz, Ana Poza, Amaia Iñurrieta, Eddita Fernández‐Díaz, Marta Arroyo, Ignacio Ramiro Martín Domínguez, Francisco Javier Candel   +6 more
openalex   +1 more source

SMart Nanoparticle–Hydrogel Hybrid System for Synergistic Eradication of Infection and Promotion of Wound Healing

Advanced Science, EarlyView.
The integrated system, comprising bacterial‐targeted photothermal nanoparticles (Fe2O3‐CS@RBP) and multifunctional hydrogels (PAOC‐3@BA) modules, achieves rapid wound healing within one week. This work introduces a smart therapeutic platform that integrates bacterial targeting, self‐regulating photothermal therapy, tissue adhesion, and stimulus ...
Hongping Wan, Huirong Tan, Xinghong Zhao
wiley   +1 more source

Chemical Synthesis of Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii Capsular Polysaccharide Fragments as Leads for Cross‐Protection

Angewandte Chemie, EarlyView.
A total of 16 chemically synthesized capsular polysaccharide (CPS) fragments related to Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii were analyzed by glycan microarray. Comparative screening revealed three conserved epitopes that act as cross‐protective vaccine lead candidates against multidrug‐resistant (MDR) bacterial ...
Amar Kumar Mishra, Emelie E. Reuber, Diksha Rai, Leif E. Sander, Julia Duerr, Simon Y. Graeber, Marcus A. Mall, Bettina C. Fries, Peter H. Seeberger, Suvarn S. Kulkarni   +9 more
wiley   +2 more sources

Methicillin-ResistantStaphylococcus aureusin Poultry

Emerging Infectious Diseases, 2009
Methicillin-resistant Staphylococcus aureus (MRSA) has been detected in several species and animal-derived products. To determine whether MRSA is present in poultry, we sampled 50 laying hens and 75 broiler chickens. MRSA was found in some broiler chickens but no laying hens. In all samples, spa type t1456 was found.
Persoons, Davy, Van Hoorebeke, Sebastiaan, Hermans, Katleen, Butaye, Patrick, de Kruif, Aart, Haesebrouck, Freddy, Dewulf, Jeroen   +6 more
openaire   +4 more sources

Photothermal–Immunomodulatory Hydrogel Reinforced by Ti3C2/ZnAl‐LDH Nanoplatform for Eradicating MRSA and Promoting Diabetic Wound Healing

Advanced Science, EarlyView.
A NETs‐inspired Ti3C2/LDH hydrogel integrates trapping, ROS boosting, and M2‐immunomodulation for MRSA‐infected wound repair. ABSTRACT MRSA infections give rise to chronic cutaneous and advance into profound tissue invasions, including osteomyelitis and sepsis—conditions for which existing clinical interventions offer only limited efficacy. The utility
Qiang Shi, Renliang Zhao, Jia Wang, Zhenchen Xiong, Xiangtian Deng, Cheng Zheng, Wenzhi Zhang   +6 more
wiley   +1 more source

Prevalence and Antibiogram of Methicillin Sensitive and Methicillin Resistant Staphylococcus aureus Isolated from Pus Samples in a Tertiary Care Teaching Hospital

Journal of Pure and Applied Microbiology, 2018
Staphylococcus aureus is an important pathogen causing bacterial infection of skin lesions, such as burns, traumatic lesions, diabetic ulcers and post operative infections.
Sowmya Govindanahalli Shivappa, Raghavendra Rao Morubagal, Rashmi Padmanabha Mahale, Ranjitha Shankare Gowda   +3 more
doaj   +1 more source

Multidrug-resistant organisms may be associated with bed allocation and utilization efficiency in healthcare institutions, based on national monitoring data from China (2014–2020)

Scientific Reports, 2023
Analyzing the influence of the bed allocation and utilization efficiency in healthcare institutions on the isolation proportion of Multidrug-resistant organisms (MDROs) to provide data to support prevention and control of MDROs.
Xing-Tian Wang, Hua Meng, Dong-Feng Pan, Xiao-Yu Zheng, Wen-Wen Lu, Chen Chen, Ming Su, Xin-Ya Su, Zhuo Liu, Xiao-Juan Ma, Pei-Feng Liang   +10 more
doaj   +1 more source